An incoherent regulatory network architecture that orchestrates B cell diversification in response to antigen signaling. - Test2 - elhamkhani - TriplyDB

An incoherent regulatory network architecture that orchestrates B cell diversification in response to antigen signaling.

An incoherent regulatory network architecture that orchestrates B cell diversification in response to antigen signaling.

http://www.wikidata.org/entity/Q35088890

about

Modeling the epigenetic attractors landscape: toward a post-genomic mechanistic understanding of development Global marine bacterial diversity peaks at high latitudes in winter Diacylglycerol kinase ζ limits B cell antigen receptor-dependent activation of ERK signaling to inhibit early antibody responses Germinal center selection and the development of memory B and plasma cells.A simple theoretical framework for understanding heterogeneous differentiation of CD4+ T cells.The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation.The generation of antibody-secreting plasma cells.Dynamics of B cells in germinal centres.Quantitative modeling of the terminal differentiation of B cells and mechanisms of lymphomagenesis.Stochastic Measurement Models for Quantifying Lymphocyte Responses Using Flow Cytometry A Network Model to Describe the Terminal Differentiation of B Cells An N-terminal mutation of the Foxp3 transcription factor alleviates arthritis but exacerbates diabetes.Irreversibility of T-Cell Specification: Insights from Computational Modelling of a Minimal Network Architecture.Structural Studies of IRF4 Reveal a Flexible Autoinhibitory Region and a Compact Linker Domain Asymmetric PI3K Signaling Driving Developmental and Regenerative Cell Fate Bifurcation.Ultrasensitivity of the Bacillus subtilis sporulation decision.All-or-none suppression of B cell terminal differentiation by environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin.Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4 Reversing endogenous alloreactive B cell GC responses with anti-CD154 or CTLA-4Ig.Systems biological approaches to measure and understand vaccine immunity in humans.Recent progress using systems biology approaches to better understand molecular mechanisms of immunity.IRF4 controls the positioning of mature B cells in the lymphoid microenvironments by regulating NOTCH2 expression and activity.Regulation of the IL-10-driven macrophage phenotype under incoherent stimuli Transcription factor IRF4 drives dendritic cells to promote Th2 differentiation.Establishing the stem cell state: insights from regulatory network analysis of blood stem cell development.The diverse roles of IRF4 in late germinal center B-cell differentiation.The 1-1-1 fallacy.Orchestration of plasma cell differentiation by Bach2 and its gene regulatory network.IRF4 and IRF8: Governing the virtues of B Lymphocytes.Transcription factors regulating B cell fate in the germinal centre.IRF4 Deficiency Leads to Altered BCR Signalling Revealed by Enhanced PI3K Pathway, Decreased SHIP Expression and Defected Cytoskeletal Responses.A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling.Short-term information processing, long-term responses: Insights by mathematical modeling of signal transduction. Early activation dynamics of key signaling mediators can be predictive for cell fate decisions.The IRF4 Gene Regulatory Module Functions as a Read-Write Integrator to Dynamically Coordinate T Helper Cell Fate.Regulation of bifurcating B cell trajectories by mutual antagonism between transcription factors IRF4 and IRF8.The Transcriptional Regulation of Germinal Center Formation Simulation of the Dynamics of Primary Immunodeficiencies in B Cells

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P2860

An incoherent regulatory network architecture that orchestrates B cell diversification in response to antigen signaling.

http://www.wikidata.org/entity/Q35088890

description

2011 nî lūn-bûn

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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2011 թվականի մայիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

An incoherent regulatory netwo ...... response to antigen signaling.

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An incoherent regulatory netwo ...... response to antigen signaling.

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An incoherent regulatory netwo ...... response to antigen signaling.

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An incoherent regulatory netwo ...... response to antigen signaling.

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An incoherent regulatory netwo ...... response to antigen signaling.

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An incoherent regulatory netwo ...... response to antigen signaling.

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Molecular Systems Biology

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An incoherent regulatory netwo ...... response to antigen signaling

@en

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Aaron R Dinner

http://www.w3.org/2001/XMLSchema#string

Harinder Singh

http://www.w3.org/2001/XMLSchema#string

Roger Sciammas

http://www.w3.org/2001/XMLSchema#string

Ying Li

http://www.w3.org/2001/XMLSchema#string

Yiqiang Song

http://www.w3.org/2001/XMLSchema#string

P2860

Diversity-generating retroelements

Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program

Modular nature of Blimp-1 in the regulation of gene expression during B cell maturation

An excitable gene regulatory circuit induces transient cellular differentiation

AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

Disruption of the Bcl6 gene results in an impaired germinal center formation

Direct repression of prdm1 by Bcl-6 inhibits plasmacytic differentiation

Control of inflammation, cytokine expression, and germinal center formation by BCL-6

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

Network motifs: simple building blocks of complex networks

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495

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10.1038/MSB.2011.25

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7

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Aryeh Warmflash

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2011-05-01T00:00:00Z

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51166609

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21613984

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3130558

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