JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation.
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Post-translational hydroxylation by 2OG/Fe(II)-dependent oxygenases as a novel regulatory mechanism in bacteriaThe epigenetic modifier JMJD6 is amplified in mammary tumors and cooperates with c-Myc to enhance cellular transformation, tumor progression, and metastasisJMJD6 and U2AF65 co-regulate alternative splicing in both JMJD6 enzymatic activity dependent and independent manner.Role of JMJD6 in Breast Tumourigenesis.JMJD5 is a potential oncogene for colon carcinogenesis.JmjC Domain-containing Protein 6 (Jmjd6) Derepresses the Transcriptional Repressor Transcription Factor 7-like 1 (Tcf7l1) and Is Required for Body Axis Patterning during Xenopus Embryogenesis.Transcriptional and post-transcriptional control of adipocyte differentiation by Jumonji domain-containing protein 6.Intronic regulation of Aire expression by Jmjd6 for self-tolerance induction in the thymusGlobal gene expression profiling of JMJD6- and JMJD4-depleted mouse NIH3T3 fibroblasts.Epigenetic silencing of JMJD5 promotes the proliferation of hepatocellular carcinoma cells by down-regulating the transcription of CDKN1A 686.PCAF-mediated acetylation of transcriptional factor HOXB9 suppresses lung adenocarcinoma progression by targeting oncogenic protein JMJD6.Jmjd6, a JmjC Dioxygenase with Many Interaction Partners and Pleiotropic FunctionsThe oxygenase Jmjd6--a case study in conflicting assignments.Bifunctional Enzyme JMJD6 Contributes to Multiple Disease Pathogenesis: New Twist on the Old Story.Insights into Jumonji C-domain containing protein 6 (JMJD6): a multifactorial role in foot-and-mouth disease virus replication in cells.Elevated expression of JMJD6 is associated with oral carcinogenesis and maintains cancer stemness propertiesProtein arginine methylation/demethylation and cancer.New Insights into Protein Hydroxylation and Its Important Role in Human Diseases.Protein arginine methylation: a prominent modification and its demethylation.Jumonji domain containing protein 6 (Jmjd6) modulates splicing and specifically interacts with arginine-serine-rich (RS) domains of SR- and SR-like proteins.PRMT5- mediated symmetric arginine dimethylation is attenuated by mutant huntingtin and is impaired in Huntington's disease (HD).Evolution and conservation of JmjC domain proteins in the green lineage.JMJD6 promotes melanoma carcinogenesis through regulation of the alternative splicing of PAK1, a key MAPK signaling component.Structural Mechanism of the Oxygenase JMJD6 Recognition by the Extraterminal (ET) Domain of BRD4.Histone arginine demethylase JMJD6 is linked to stress granule assembly through demethylation of the stress granule-nucleating protein G3BP1.Clipping of arginine-methylated histone tails by JMJD5 and JMJD7.JMJD6 induces HOTAIR, an oncogenic lincRNA, by physically interacting with its proximal promoter.Demethylase JMJD6 as a New Regulator of Interferon Signaling: Effects of HCV and Ethanol Metabolism.The Krebs Cycle Connection: Reciprocal Influence Between Alternative Splicing Programs and Cell Metabolism
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P2860
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation.
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2014 nî lūn-bûn
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2014 թուականի Մարտին հրատարակուած գիտական յօդուած
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2014 թվականի մարտին հրատարակված գիտական հոդված
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年學術文章
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name
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation.
@ast
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation.
@en
type
label
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation.
@ast
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation.
@en
prefLabel
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation.
@ast
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation.
@en
P2093
P2860
P1433
P1476
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation.
@en
P2093
Luyang Sun
Peiwei Huangyang
Ruorong Yan
Shumeng Liu
P2860
P304
P356
10.1371/JOURNAL.PBIO.1001819
P407
P577
2014-03-25T00:00:00Z