The role of insulin-like growth factor-I in the physiopathology of hearing.
about
Human conditions of insulin-like growth factor-I (IGF-I) deficiencyEarly development of the vertebrate inner earEarly otic development depends on autophagy for apoptotic cell clearance and neural differentiation.Insulin receptor substrate 2 (IRS2)-deficient mice show sensorineural hearing loss that is delayed by concomitant protein tyrosine phosphatase 1B (PTP1B) loss of functionTreatment with N- and C-terminal peptides of parathyroid hormone-related protein partly compensate the skeletal abnormalities in IGF-I deficient mice.The minimum peptides of IGF-1 and substance P protect vestibular hair cells against neomycin ototoxicity.Expression of insulin signalling components in the sensory epithelium of the human saccule.IGF-1 deficiency causes atrophic changes associated with upregulation of VGluT1 and downregulation of MEF2 transcription factors in the mouse cochlear nuclei.Upregulation of the Na⁺-coupled phosphate cotransporters NaPi-IIa and NaPi-IIb by B-RAF.An experimental model of partial insulin-like growth factor-1 deficiency in mice.The Role of Insulin-Like Growth Factor 1 in the Progression of Age-Related Hearing Loss.
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P2860
The role of insulin-like growth factor-I in the physiopathology of hearing.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The role of insulin-like growth factor-I in the physiopathology of hearing.
@ast
The role of insulin-like growth factor-I in the physiopathology of hearing.
@en
type
label
The role of insulin-like growth factor-I in the physiopathology of hearing.
@ast
The role of insulin-like growth factor-I in the physiopathology of hearing.
@en
prefLabel
The role of insulin-like growth factor-I in the physiopathology of hearing.
@ast
The role of insulin-like growth factor-I in the physiopathology of hearing.
@en
P2093
P2860
P356
P1476
The role of insulin-like growth factor-I in the physiopathology of hearing
@en
P2093
Isabel Varela-Nieto
Luis Lassaletta
Rafael Cediel
Silvia Murillo-Cuesta
P2860
P356
10.3389/FNMOL.2011.00011
P577
2011-07-25T00:00:00Z