DAX-1, an unusual orphan receptor at the crossroads of steroidogenic function and sexual differentiation.
about
Melanoma antigen gene protein MAGE-11 regulates androgen receptor function by modulating the interdomain interactionDAX-1 expression in human breast cancer: comparison with estrogen receptors ER-alpha, ER-beta and androgen receptor statusDAX-1 (NR0B1) and steroidogenic factor-1 (SF-1, NR5A1) in human diseaseStructural insights into corepressor recognition by antagonist-bound estrogen receptorsThe structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1Conditional deletion of the retinoblastoma (Rb) gene in ovarian granulosa cells leads to premature ovarian failure.Functional biology of the primate fetal adrenal gland: advances in technology provide new insight.Tumorigenic role of orphan nuclear receptor NR0B1 in lung adenocarcinomaSomatic mutations and progressive monosomy modify SAMD9-related phenotypes in humans.Development and function of the human fetal adrenal cortex: a key component in the feto-placental unit.Inhibition of cyclin D1 expression by androgen receptor in breast cancer cells--identification of a novel androgen response element.Identification of male gametogenesis expressed genes from the scallop Nodipecten subnodosus by suppressive subtraction hybridization and pyrosequencing.Evidence of adrenal failure in aging Dax1-deficient mice.Inherited adrenal hypoplasia: not just for kids!Adrenocortical cells with stem/progenitor cell properties: recent advances.A pleiotropic role for the orphan nuclear receptor small heterodimer partner in lipid homeostasis and metabolic pathways.Notch signaling represses GATA4-induced expression of genes involved in steroid biosynthesisAdrenocortical stem and progenitor cells: unifying model of two proposed origins.The orphan nuclear receptor DAX-1 functions as a potent corepressor of the constitutive androstane receptor (NR1I3).Mechanisms of Disease: normal and abnormal gonadal development and sex determination in mammals.Minireview: the diverse roles of nuclear receptors in the regulation of embryonic stem cell pluripotency.Developmental links between the fetal and adult zones of the adrenal cortex revealed by lineage tracing.DAX-1A (NR0B1A) expression levels are extremely low compared to DAX-1 (NR0B1) in human steroidogenic tissues.DAX-1, as an androgen-target gene, inhibits aromatase expression: a novel mechanism blocking estrogen-dependent breast cancer cell proliferationRole of dosage-sensitive sex reversal, adrenal hypoplasia congenita, critical region on the X chromosome, gene 1 in protein kinase A- and protein kinase C-mediated regulation of the steroidogenic acute regulatory protein expression in mouse Leydig tIn search of adrenocortical stem and progenitor cellsDe novo synthesis of steroids and oxysterols in adipocytesEWS/FLI and its downstream target NR0B1 interact directly to modulate transcription and oncogenesis in Ewing's sarcoma.Minireview: role of orphan nuclear receptors in cancer and potential as drug targetsTargeting DAX-1 in embryonic stem cells and cancer.Expression of nuclear receptor DAX-1 and androgen receptor in human breast cancer.The orphan nuclear receptors at their 25-year reunion.Steroidogenesis-adrenal cell signal transduction.Adrenocortical growth and cancer.The orphan nuclear receptor DAX1 is up-regulated by the EWS/FLI1 oncoprotein and is highly expressed in Ewing tumors.EWS/FLI1 Target Genes and Therapeutic Opportunities in Ewing Sarcoma.The Battle of the Sexes: Human Sex Development and Its Disorders.Nuclear receptor 4A (NR4A) family - orphans no more.E3 ubiquitin ligase RNF31 cooperates with DAX-1 in transcriptional repression of steroidogenesisInsights into the binding mode and mechanism of action of some atypical retinoids as ligands of the small heterodimer partner (SHP).
P2860
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P2860
DAX-1, an unusual orphan receptor at the crossroads of steroidogenic function and sexual differentiation.
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
DAX-1, an unusual orphan recep ...... on and sexual differentiation.
@ast
DAX-1, an unusual orphan recep ...... on and sexual differentiation.
@en
type
label
DAX-1, an unusual orphan recep ...... on and sexual differentiation.
@ast
DAX-1, an unusual orphan recep ...... on and sexual differentiation.
@en
prefLabel
DAX-1, an unusual orphan recep ...... on and sexual differentiation.
@ast
DAX-1, an unusual orphan recep ...... on and sexual differentiation.
@en
P356
P1476
DAX-1, an unusual orphan recep ...... on and sexual differentiation.
@en
P304
P356
10.1210/ME.2003-0159
P577
2003-05-29T00:00:00Z