HDAC inhibition prevents white matter injury by modulating microglia/macrophage polarization through the GSK3β/PTEN/Akt axis. - Test2 - elhamkhani - TriplyDB

HDAC inhibition prevents white matter injury by modulating microglia/macrophage polarization through the GSK3β/PTEN/Akt axis.

HDAC inhibition prevents white matter injury by modulating microglia/macrophage polarization through the GSK3β/PTEN/Akt axis.

http://www.wikidata.org/entity/Q35157022

about

Oligodendrocyte, Astrocyte, and Microglia Crosstalk in Myelin Development, Damage, and Repair Epigenetic Control of Macrophage Polarisation and Soluble Mediator Gene Expression during Inflammation Class I PI3K inhibitor ZSTK474 mediates a shift in microglial/macrophage phenotype and inhibits inflammatory response in mice with cerebral ischemia/reperfusion injury.Microglia processes associate with diffusely injured axons following mild traumatic brain injury in the micro pig.CD200 restrains macrophage attack on oligodendrocyte precursors via toll-like receptor 4 downregulation.Molecular Targets for PET Imaging of Activated Microglia: The Current Situation and Future Expectations.Pharmacological Modulation of Functional Phenotypes of Microglia in Neurodegenerative Diseases Microglial Activation in Traumatic Brain Injury.Administration of Tauroursodeoxycholic Acid Attenuates Early Brain Injury via Akt Pathway Activation Imaging of Glial Cell Activation and White Matter Integrity in Brains of Active and Recently Retired National Football League Players.Galectin-1-secreting neural stem cells elicit long-term neuroprotection against ischemic brain injury Mapping the Connectome Following Traumatic Brain Injury.Demyelination as a rational therapeutic target for ischemic or traumatic brain injury.White matter injury and microglia/macrophage polarization are strongly linked with age-related long-term deficits in neurological function after stroke.Modeling Chronic Traumatic Encephalopathy: The Way Forward for Future Discovery.Cytosolic phospholipase A2 plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway.Microglia in the TBI brain: The good, the bad, and the dysregulated.Alternatively activated macrophages determine repair of the infarcted adult murine heart.APE1/Ref-1 facilitates recovery of gray and white matter and neurological function after mild stroke injury.Epigenetics of amphetamine-induced sensitization: HDAC5 expression and microRNA in neural remodeling Electroacupuncture Promotes Remyelination after Cuprizone Treatment by Enhancing Myelin Debris Clearance.Suppression of Excessive Histone Deacetylases Activity in Diabetic Hearts Attenuates Myocardial Ischemia/Reperfusion Injury via Mitochondria Apoptosis Pathway.Potential involvement of glycogen synthase kinase (GSK)-3β in a rat model of multiple sclerosis: evidenced by lithium treatment Brain-peripheral cell crosstalk in white matter damage and repair.A three-signal model of T-cell lymphoma pathogenesis Changing paradigm to target microglia in neurodegenerative diseases: from anti-inflammatory strategy to active immunomodulation.Minocycline plus N-acteylcysteine induces remyelination, synergistically protects oligodendrocytes, and modifies neuroinflammation in a rat model of mild traumatic brain injury.Immunosenescence of microglia and macrophages: impact on the ageing central nervous system.MicroRNA-21 promotes phosphatase gene and protein kinase B/phosphatidylinositol 3-kinase expression in colorectal cancer.Interleukin-17A neutralization alleviated ocular neovascularization by promoting M2 and mitigating M1 macrophage polarization.Histone deacetylases function as a novel potential therapeutic target for cancer.Macrophage polarization in response to epigenetic modifiers during infection and inflammation.Regulation of Nitrogen Mustard-Induced Lung Macrophage Activation by Valproic Acid, a Histone Deacetylase Inhibitor.Modulators of microglial activation and polarization after intracerebral haemorrhage.Dynamic impact of brief electrical nerve stimulation on the neural immune axis-polarization of macrophages toward a pro-repair phenotype in demyelinated peripheral nerve.Dimethyl fumarate improves white matter function following severe hypoperfusion: Involvement of microglia/macrophages and inflammatory mediators.Effects of Erythropoietin on Gliogenesis during Cerebral Ischemic/Reperfusion Recovery in Adult Mice.Repetitive and Prolonged Omega-3 Fatty Acid Treatment After Traumatic Brain Injury Enhances Long-Term Tissue Restoration and Cognitive Recovery.Caveolin-1 Protects Retinal Ganglion Cells against Acute Ocular Hypertension Injury via Modulating Microglial Phenotypes and Distribution and Activating AKT pathway.Implantation of Brain-Derived Extracellular Matrix Enhances Neurological Recovery after Traumatic Brain Injury.

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P2860

HDAC inhibition prevents white matter injury by modulating microglia/macrophage polarization through the GSK3β/PTEN/Akt axis.

http://www.wikidata.org/entity/Q35157022

description

2015 nî lūn-bûn

@nan

2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2015年の論文

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2015年論文

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2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

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2015年论文

@wuu

name

HDAC inhibition prevents white ...... rough the GSK3β/PTEN/Akt axis.

@ast

HDAC inhibition prevents white ...... rough the GSK3β/PTEN/Akt axis.

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type

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HDAC inhibition prevents white ...... rough the GSK3β/PTEN/Akt axis.

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HDAC inhibition prevents white ...... rough the GSK3β/PTEN/Akt axis.

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prefLabel

HDAC inhibition prevents white ...... rough the GSK3β/PTEN/Akt axis.

@ast

HDAC inhibition prevents white ...... rough the GSK3β/PTEN/Akt axis.

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Proceedings of the National Academy of Sciences of the United States of America

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HDAC inhibition prevents white ...... hrough the GSK3β/PTEN/Akt axis

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Bo Tang

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Guohua Wang

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Hongjian Pu

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Jun Chen

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Michael V L Bennett

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Ping Zheng

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Wei-Wei Li

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Xiaoming Hu

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Xiaoyan Jiang

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Yanqin Gao

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P2860

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

HDAC inhibitors as anti-inflammatory agents

Histone deacetylases and their role in motor neuron degeneration

Valproate administered after traumatic brain injury provides neuroprotection and improves cognitive function in rats

Characterization of fractalkine in rat brain cells: migratory and activation signals for CX3CR-1-expressing microglia

Temporal changes in cell marker expression and cellular infiltration in a controlled cortical impact model in adult male C57BL/6 mice

Histone deacetylase inhibitor ITF2357 is neuroprotective, improves functional recovery, and induces glial apoptosis following experimental traumatic brain injury.

HDAC inhibitors mitigate ischemia-induced oligodendrocyte damage: potential roles of oligodendrogenesis, VEGF, and anti-inflammation

Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies

Role of microglia in neurotrauma.

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