Polyubiquitin binding to ABIN1 is required to prevent autoimmunity. - Test2 - elhamkhani - TriplyDB

Polyubiquitin binding to ABIN1 is required to prevent autoimmunity.

Polyubiquitin binding to ABIN1 is required to prevent autoimmunity.

http://www.wikidata.org/entity/Q35213554

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Regulation of nuclear factor-κB in autoimmunity Toll-like receptors in systemic lupus erythematosus: potential targets for therapeutic intervention Clinical perspectives on lupus genetics: advances and opportunities The TLR and IL-1 signalling network at a glance NF-κB in inflammation and renal diseases A20-Binding Inhibitor of NF-κB Activation 1 is a Physiologic Inhibitor of NF-κB: A Molecular Switch for Inflammation and Autoimmunity The catalytic subunit of the system L1 amino acid transporter (slc7a5) facilitates nutrient signalling in mouse skeletal muscle Linear ubiquitination in immunity Does antigen masking by ubiquitin chains protect from the development of autoimmune diseases?A20-binding inhibitor of NF-κB (ABIN1) controls Toll-like receptor-mediated CCAAT/enhancer-binding protein β activation and protects from inflammatory disease Risk for myasthenia gravis maps to a (151) Pro→Ala change in TNIP1 and to human leukocyte antigen-B*08 Emergence of the A20/ABIN-mediated inhibition of NF-κB signaling via modifying the ubiquitinated proteins in a basal chordate.Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.Do follicular dendritic cells regulate lupus-specific B cells?TNIP1 reduction of HSPA6 gene expression occurs in promoter regions lacking binding sites for known TNIP1-repressed transcription factors An important role for A20-binding inhibitor of nuclear factor-kB-1 (ABIN1) in inflammation-mediated endothelial dysfunction: an in vivo study in ABIN1 (D485N) mice The TRAF-associated protein TANK facilitates cross-talk within the IkappaB kinase family during Toll-like receptor signaling.ABIN1 protein cooperates with TAX1BP1 and A20 proteins to inhibit antiviral signaling.Downregulation of TNIP1 Expression Leads to Increased Proliferation of Human Keratinocytes and Severer Psoriasis-Like Conditions in an Imiquimod-Induced Mouse Model of Dermatitis Emerging roles for TNIP1 in regulating post-receptor signaling Association of two independent functional risk haplotypes in TNIP1 with systemic lupus erythematosus.A20: linking a complex regulator of ubiquitylation to immunity and human disease The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system.Genetic susceptibility to lupus: the biological basis of genetic risk found in B cell signaling pathways.ABIN1 dysfunction as a genetic basis for lupus nephritis.Two phases of inflammatory mediator production defined by the study of IRAK2 and IRAK1 knock-in mice.Suppression of IRAK1 or IRAK4 Catalytic Activity, but Not Type 1 IFN Signaling, Prevents Lupus Nephritis in Mice Expressing a Ubiquitin Binding-Defective Mutant of ABIN1 Immune regulator ABIN1 suppresses HIV-1 transcription by negatively regulating the ubiquitination of Tat.Regulation of NF-κB signaling by the A20 deubiquitinase.The emerging role of linear ubiquitination in cell signaling.Integration of B cell responses through Toll-like receptors and antigen receptors.Ubiquitination in signaling to and activation of IKK.Regulation of NF-κB by deubiquitinases.Negative regulation of human mononuclear phagocyte function.Molecular control of the NEMO family of ubiquitin-binding proteins.Protein kinase networks that limit TLR signalling.The deubiquitinase A20 in immunopathology of autoimmune diseases.Immune diseases caused by mutations in kinases and components of the ubiquitin system.Met1-linked ubiquitination in immune signalling.Risk factors for renal disease in systemic lupus erythematosus and their clinical implications.

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P2860

Polyubiquitin binding to ABIN1 is required to prevent autoimmunity.

http://www.wikidata.org/entity/Q35213554

description

2011 nî lūn-bûn

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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2011 թվականի մայիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年學術文章

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name

Polyubiquitin binding to ABIN1 is required to prevent autoimmunity.

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Polyubiquitin binding to ABIN1 is required to prevent autoimmunity.

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type

label

Polyubiquitin binding to ABIN1 is required to prevent autoimmunity.

@ast

Polyubiquitin binding to ABIN1 is required to prevent autoimmunity.

@en

prefLabel

Polyubiquitin binding to ABIN1 is required to prevent autoimmunity.

@ast

Polyubiquitin binding to ABIN1 is required to prevent autoimmunity.

@en

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Journal of Experimental Medicine

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Polyubiquitin binding to ABIN1 is required to prevent autoimmunity.

@en

P2093

Alban Ordureau

http://www.w3.org/2001/XMLSchema#string

David W Powell

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J Simon C Arthur

http://www.w3.org/2001/XMLSchema#string

Janet C Patterson-Kane

http://www.w3.org/2001/XMLSchema#string

Philip Cohen

http://www.w3.org/2001/XMLSchema#string

Rachel Toth

http://www.w3.org/2001/XMLSchema#string

Ram K C Venigalla

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Sambit K Nanda

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P2860

TRAF6 autoubiquitination-independent activation of the NFkappaB and MAPK pathways in response to IL-1 and RANKL

Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

A ubiquitin ligase complex assembles linear polyubiquitin chains

Ubiquitin binding mediates the NF-kappaB inhibitory potential of ABIN proteins

Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function

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10.1084/JEM.20102177

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6

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208

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2011-05-23T00:00:00Z

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51159967

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21606507

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3173241

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