A20: linking a complex regulator of ubiquitylation to immunity and human disease
about
Interleukin-33 and Mast Cells Bridge Innate and Adaptive Immunity: From the Allergologist's PerspectiveTNF biology, pathogenic mechanisms and emerging therapeutic strategiesRegulation of nuclear factor-κB in autoimmunityNF-κB in inflammation and renal diseasesRegulation of NF-κB by ubiquitinationTNFAIP3 promotes survival of CD4 T cells by restricting MTOR and promoting autophagyThe IL-23-IL-17 immune axis: from mechanisms to therapeutic testingDeubiquitinases: Novel Therapeutic Targets in Immune Surveillance?Immunoregulatory Effects Triggered by Lactic Acid Bacteria Exopolysaccharides: New Insights into Molecular Interactions with Host CellsLinear ubiquitination in immunityThe role of aberrant proteolysis in lymphomagenesisTCR signaling to NF-κB and mTORC1: Expanding roles of the CARMA1 complexBiallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory diseaseThe polymorphisms of tumor necrosis factor-induced protein 3 gene may contribute to the susceptibility of chronic primary immune thrombocytopenia in Chinese population.Emergence of the A20/ABIN-mediated inhibition of NF-κB signaling via modifying the ubiquitinated proteins in a basal chordate.MYD88 L265P mutations are correlated with 6q deletion in Korean patients with Waldenström macroglobulinemiaTNFAIP3 gene rs7749323 polymorphism is associated with late onset myasthenia gravis.Oscillation dynamics underlie functional switching of NF-κB for B-cell activation.Biphasic regulation of A20 gene expression during human cytomegalovirus infection.Functional effect of polymorphisms in the promoter of TNFAIP3 (A20) in acute pancreatitis in the Han Chinese populationThe tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20) imposes a brake on antitumor activity of CD8 T cellsNOD2 downregulates colonic inflammation by IRF4-mediated inhibition of K63-linked polyubiquitination of RICK and TRAF6.Dendritic cell maturation: functional specialization through signaling specificity and transcriptional programmingIntestinal epithelial expression of TNFAIP3 results in microbial invasion of the inner mucus layer and induces colitis in IL-10-deficient mice.Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children.The signaling adaptor TRAF1 negatively regulates Toll-like receptor signaling and this underlies its role in rheumatic disease.Identification of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2.A20 restricts wnt signaling in intestinal epithelial cells and suppresses colon carcinogenesis.How informative is the mouse for human gut microbiota research?The anaphase-promoting complex protein 5 (AnapC5) associates with A20 and inhibits IL-17-mediated signal transduction.Role and therapeutic value of dendritic cells in central nervous system autoimmunity.A20 restricts ubiquitination of pro-interleukin-1β protein complexes and suppresses NLRP3 inflammasome activity.Lack of the ubiquitin-editing enzyme A20 results in loss of hematopoietic stem cell quiescenceAssociation between TNFAIP3 nonsynonymous single-nucleotide polymorphism rs2230926 and chronic hepatitis B virus infection in a Chinese Han population.The effects of the microbiota on the host immune system.The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosisBacterial secretions of nonpathogenic Escherichia coli elicit inflammatory pathways: a closer investigation of interkingdom signaling.Moderate activation of IKK2-NF-kB in unstressed adult mouse liver induces cytoprotective genes and lipogenesis without apparent signs of inflammation or fibrosis.Overexpression of MALT1-A20-NF-κB in adult B-cell acute lymphoblastic leukemiaA20 Deficiency in Lung Epithelial Cells Protects against Influenza A Virus Infection
P2860
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P2860
A20: linking a complex regulator of ubiquitylation to immunity and human disease
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
A20: linking a complex regulator of ubiquitylation to immunity and human disease
@ast
A20: linking a complex regulator of ubiquitylation to immunity and human disease
@en
type
label
A20: linking a complex regulator of ubiquitylation to immunity and human disease
@ast
A20: linking a complex regulator of ubiquitylation to immunity and human disease
@en
prefLabel
A20: linking a complex regulator of ubiquitylation to immunity and human disease
@ast
A20: linking a complex regulator of ubiquitylation to immunity and human disease
@en
P2860
P356
P1476
A20: linking a complex regulator of ubiquitylation to immunity and human disease
@en
P2093
Barbara A Malynn
P2860
P304
P356
10.1038/NRI3313
P577
2012-10-12T00:00:00Z