Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic beta cells.
about
Regulation of PKD by the MAPK p38delta in insulin secretion and glucose homeostasisA novel lipid-anchored A-kinase Anchoring Protein facilitates cAMP-responsive membrane eventsInsulin secretion: a high-affinity Ca2+ sensor after all?Beta-cell CaV channel regulation in physiology and pathophysiology.Capacitance measurements of exocytosis in mouse pancreatic alpha-, beta- and delta-cells within intact islets of Langerhans.Inhibition of pancreatic β-cell Ca2+/calmodulin-dependent protein kinase II reduces glucose-stimulated calcium influx and insulin secretion, impairing glucose tolerance.Stimulation of exocytosis without a calcium signal.Expression and regulation of cyclic nucleotide phosphodiesterases in human and rat pancreatic islets.Effects of serine/threonine protein phosphatases on ion channels in excitable membranes.Dissociation between changes in cytoplasmic free Ca2+ concentration and insulin secretion as evidenced from measurements in mouse single pancreatic islets.Fusion pore expansion in horse eosinophils is modulated by Ca2+ and protein kinase C via distinct mechanisms.Phosphorylation of myristoylated alanine-rich C kinase substrate (MARCKS) protein is associated with bovine luteal oxytocin exocytosis.Possible protective effect of membrane lipid rafts against interleukin-1β-mediated anti-proliferative effect in INS-1 cells.Molecular mechanisms of protein induced hyperinsulinaemic hypoglycaemia.Distinct potentiation of L-type currents and secretion by cAMP in rat chromaffin cellsLong-term potentiation of exocytosis and cell membrane repair in fibroblastsPost-priming actions of ATP on Ca2+-dependent exocytosis in pancreatic beta cells.Inhibition of mouse neuromuscular transmission and contractile function by okadaic acid and cantharidin.The role of serine/threonine protein phosphatases in exocytosisNuclear factor κB-inducing kinase activation as a mechanism of pancreatic β cell failure in obesity.Inositol hexakisphosphate stimulates non-Ca2+-mediated and primes Ca2+-mediated exocytosis of insulin by activation of protein kinase CMultiple exocytotic pathways in pancreatic beta cells.Glucose-sensing mechanisms in pancreatic beta-cells.PKC-induced sensitization of Ca2+-dependent exocytosis is mediated by reducing the Ca2+ cooperativity in pituitary gonadotropes.A highly Ca2+-sensitive pool of granules is regulated by glucose and protein kinases in insulin-secreting INS-1 cellsAnchoring of protein kinase A facilitates hormone-mediated insulin secretionEvidence for the possible involvement of the P2Y(6) receptor in Ca (2+) mobilization and insulin secretion in mouse pancreatic islets.Regulation of calcium in pancreatic α- and β-cells in health and disease.Protein phosphatases in pancreatic islets.Modulation of Ionic Channels and Insulin Secretion by Drugs and Hormones in Pancreatic Beta Cells.Hypomethylation of the promoter of the catalytic subunit of protein phosphatase 2A in response to hyperglycemia.Noradrenaline inhibits exocytosis via the G protein βγ subunit and refilling of the readily releasable granule pool via the α(i1/2) subunit.The mechanisms of cell membrane resealing in rabbit corneal epithelial cells.Ca(2+) influx and cAMP elevation overcame botulinum toxin A but not tetanus toxin inhibition of insulin exocytosis.Co-localization of L-type Ca2+ channels and insulin-containing secretory granules and its significance for the initiation of exocytosis in mouse pancreatic B-cells.Secretagogue-dependent phosphorylation of the insulin granule membrane protein phogrin is mediated by cAMP-dependent protein kinase.Hamster pancreatic beta cell lines with altered sensitivity towards apoptotic signalling by phosphatase inhibitors.Threonine phosphorylations induced by RX-871024 and insulin secretagogues in betaTC6-F7 cells.Insulin secretagogues activate the secretory granule receptor-like protein-tyrosine phosphatase IAR.An endogenous peptide isolated from the gut, NK-lysin, stimulates insulin secretion without changes in cytosolic free Ca2+ concentration.
P2860
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P2860
Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic beta cells.
description
1994 nî lūn-bûn
@nan
1994 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Activation of protein kinases ...... n mouse pancreatic beta cells.
@ast
Activation of protein kinases ...... n mouse pancreatic beta cells.
@en
type
label
Activation of protein kinases ...... n mouse pancreatic beta cells.
@ast
Activation of protein kinases ...... n mouse pancreatic beta cells.
@en
prefLabel
Activation of protein kinases ...... n mouse pancreatic beta cells.
@ast
Activation of protein kinases ...... n mouse pancreatic beta cells.
@en
P2093
P2860
P50
P356
P1476
Activation of protein kinases ...... in mouse pancreatic beta cells
@en
P2093
P2860
P304
P356
10.1073/PNAS.91.10.4343
P407
P577
1994-05-01T00:00:00Z