A constitutively activated mutant of human soluble guanylyl cyclase (sGC): implication for the mechanism of sGC activation.
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Insights into BAY 60-2770 Activation and S -Nitrosylation-Dependent Desensitization of Soluble Guanylyl Cyclase via Crystal Structures of Homologous Nostoc H-NOX Domain ComplexesIdentification of residues in the heme domain of soluble guanylyl cyclase that are important for basal and stimulated catalytic activityPyridopyrimidine derivatives as inhibitors of cyclic nucleotide synthesis: Application for treatment of diarrhea.The fibrate gemfibrozil is a NO- and haem-independent activator of soluble guanylyl cyclase: in vitro studies.A high-throughput fluorimetric assay for 2-hydroxyglutarate identifies Zaprinast as a glutaminase inhibitor.CCTeta, a novel soluble guanylyl cyclase-interacting protein.Oxygen mediates vascular smooth muscle relaxation in hypoxiaRestoring soluble guanylyl cyclase expression and function blocks the aggressive course of glioma.Dynamic ligand exchange in soluble guanylyl cyclase (sGC): implications for sGC regulation and desensitization.Cobinamides are novel coactivators of nitric oxide receptor that target soluble guanylyl cyclase catalytic domain.Aspartate 102 in the heme domain of soluble guanylyl cyclase has a key role in NO activation.Cardiovascular and pharmacological implications of haem-deficient NO-unresponsive soluble guanylate cyclase knock-in mice.Role of nitric oxide and cGMP in the modulation of vascular contraction induced by angiotensin II and Bay K8644 during ischemia/reperfusionAlpha1 soluble guanylyl cyclase (sGC) splice forms as potential regulators of human sGC activityConstitutive cyclic GMP accumulation in Arabidopsis thaliana compromises systemic acquired resistance induced by an avirulent pathogen by modulating local signals.YC-1 binding to the β subunit of soluble guanylyl cyclase overcomes allosteric inhibition by the α subunit.The G-protein regulator LGN modulates the activity of the NO receptor soluble guanylate cyclaseNew conception for the development of hypertension in preeclampsia.Structures of soluble guanylate cyclase: implications for regulatory mechanisms and drug development.Disrupted nitric oxide signaling due to GUCY1A3 mutations increases risk for moyamoya disease, achalasia and hypertension.Soluble guanylyl cyclase activation by HMR-1766 (ataciguat) in cells exposed to oxidative stress.Reactive oxygen species induce tyrosine phosphorylation of and Src kinase recruitment to NO-sensitive guanylyl cyclase.Role of sulfhydryl-dependent dimerization of soluble guanylyl cyclase in relaxation of porcine coronary artery to nitric oxide.
P2860
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P2860
A constitutively activated mutant of human soluble guanylyl cyclase (sGC): implication for the mechanism of sGC activation.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
A constitutively activated mut ...... e mechanism of sGC activation.
@ast
A constitutively activated mut ...... e mechanism of sGC activation.
@en
type
label
A constitutively activated mut ...... e mechanism of sGC activation.
@ast
A constitutively activated mut ...... e mechanism of sGC activation.
@en
prefLabel
A constitutively activated mut ...... e mechanism of sGC activation.
@ast
A constitutively activated mut ...... e mechanism of sGC activation.
@en
P2093
P2860
P356
P1476
A constitutively activated mut ...... e mechanism of sGC activation.
@en
P2093
Alexander Kots
Emil Martin
Iraida Sharina
P2860
P304
P356
10.1073/PNAS.1633590100
P407
P50
P577
2003-07-25T00:00:00Z