Soluble guanylyl cyclase activation by HMR-1766 (ataciguat) in cells exposed to oxidative stress.
about
Heme-dependent and independent soluble guanylate cyclase activators and vasodilation.Increased cytochrome P4502E1 expression and altered hydroxyeicosatetraenoic acid formation mediate diabetic vascular dysfunction: rescue by guanylyl-cyclase activation.Targeting soluble guanylate cyclase for the treatment of pulmonary hypertension.Pulmonary and systemic vasodilator responses to the soluble guanylyl cyclase activator, BAY 60-2770, are not dependent on endogenous nitric oxide or reduced heme.Soluble guanylate cyclase: a new therapeutic target for pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.Oxidation and loss of heme in soluble guanylyl cyclase from Manduca sexta.NOX1, 2, 4, 5: counting out oxidative stress.Soluble guanylate cyclase redox state under oxidative stress conditions in isolated monkey coronary arteriesNovel therapeutic strategies targeting vascular endothelium in essential hypertension.Evaluating the Phase II drugs currently under investigation for diabetic neuropathy.The cGMP/PKG pathway as a common mediator of cardioprotection: translatability and mechanism.Distinct molecular requirements for activation or stabilization of soluble guanylyl cyclase upon haem oxidation-induced degradation.Activation of haem-oxidized soluble guanylyl cyclase with BAY 60-2770 in human platelets lead to overstimulation of the cyclic GMP signaling pathway.NO-independent stimulation or activation of soluble guanylyl cyclase during early reperfusion limits infarct size.Comparison of soluble guanylate cyclase stimulators and activators in models of cardiovascular disease associated with oxidative stress.Effects of hydrogen peroxide on relaxation through the NO/sGC/cGMP pathway in isolated rat iliac arteries.Structure/function of the soluble guanylyl cyclase catalytic domain.
P2860
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P2860
Soluble guanylyl cyclase activation by HMR-1766 (ataciguat) in cells exposed to oxidative stress.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
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2008年學術文章
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name
Soluble guanylyl cyclase activ ...... s exposed to oxidative stress.
@en
Soluble guanylyl cyclase activation by HMR-1766
@nl
type
label
Soluble guanylyl cyclase activ ...... s exposed to oxidative stress.
@en
Soluble guanylyl cyclase activation by HMR-1766
@nl
prefLabel
Soluble guanylyl cyclase activ ...... s exposed to oxidative stress.
@en
Soluble guanylyl cyclase activation by HMR-1766
@nl
P2093
P2860
P50
P356
P1476
Soluble guanylyl cyclase activ ...... s exposed to oxidative stress.
@en
P2093
Anastasia Pyriochou
Charis Roussos
Georgios Spyroulias
Martin van Eickels
Zongmin Zhou
P2860
P304
P356
10.1152/AJPHEART.51.2008
P577
2008-08-29T00:00:00Z