E3 ubiquitin ligase CHIP facilitates Toll-like receptor signaling by recruiting and polyubiquitinating Src and atypical PKC{zeta}. - Test2 - elhamkhani - TriplyDB

E3 ubiquitin ligase CHIP facilitates Toll-like receptor signaling by recruiting and polyubiquitinating Src and atypical PKC{zeta}.

E3 ubiquitin ligase CHIP facilitates Toll-like receptor signaling by recruiting and polyubiquitinating Src and atypical PKC{zeta}.

http://www.wikidata.org/entity/Q35237506

about

CHIP: A new modulator of human malignant disorders Current Understanding on EGFR and Wnt/β-Catenin Signaling in Glioma and Their Possible Crosstalk A Decade of Boon or Burden: What Has the CHIP Ever Done for Cellular Protein Quality Control Mechanism Implicated in Neurodegeneration and Aging?TRAF-interacting protein (TRIP) negatively regulates IFN-β production and antiviral response by promoting proteasomal degradation of TANK-binding kinase 1 The E3 ubiquitin ligase neuregulin receptor degradation protein 1 (Nrdp1) promotes M2 macrophage polarization by ubiquitinating and activating transcription factor CCAAT/enhancer-binding Protein β (C/EBPβ)Symmetry breaking during homodimeric assembly activates an E3 ubiquitin ligase Ubiquitination of inositol-requiring enzyme 1 (IRE1) by the E3 ligase CHIP mediates the IRE1/TRAF2/JNK pathway.Lys29-linkage of ASK1 by Skp1-Cullin 1-Fbxo21 ubiquitin ligase complex is required for antiviral innate response.LRRFIP2 negatively regulates NLRP3 inflammasome activation in macrophages by promoting Flightless-I-mediated caspase-1 inhibition.RNF122 suppresses antiviral type I interferon production by targeting RIG-I CARDs to mediate RIG-I degradation Herpes simplex virus 1 ICP22 but not US 1.5 is required for efficient acute replication in mice and VICE domain formation.Global functional profiling of human ubiquitome identifies E3 ubiquitin ligase DCST1 as a novel negative regulator of Type-I interferon signaling Regulation of IL-4 receptor signaling by STUB1 in lung inflammation.Extracellular calcium elicits feedforward regulation of the Toll-like receptor-triggered innate immune response.The inducible nitric-oxide synthase (iNOS)/Src axis mediates Toll-like receptor 3 tyrosine 759 phosphorylation and enhances its signal transduction, leading to interferon-β synthesis in macrophages.Peli: a family of signal-responsive E3 ubiquitin ligases mediating TLR signaling and T-cell tolerance.MicroRNAs in the regulation of TLR and RIG-I pathways.Ubiquitin links to cytoskeletal dynamics, cell adhesion and migration.Regulation of Toll-like receptor signaling pathways in innate immune responses.Regulation of innate receptor pathways by microRNAs.The E3 ligase CHIP: insights into its structure and regulation.Microbial sensing by Toll-like receptors and intracellular nucleic acid sensors.Self-regulation and cross-regulation of pattern-recognition receptor signalling in health and disease.STUB1 is essential for T-cell activation by ubiquitinating CARMA1.Multiple functions of the E3 ubiquitin ligase CHIP in immunity.HRS plays an important role for TLR7 signaling to orchestrate inflammation and innate immunity upon EV71 infection.MARCH1 E3 Ubiquitin Ligase Dampens the Innate Inflammatory Response by Modulating Monocyte Functions in Mice.Cytoplasmic STAT4 Promotes Antiviral Type I IFN Production by Blocking CHIP-Mediated Degradation of RIG-I.Stk38 protein kinase preferentially inhibits TLR9-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages.Activation of decidual invariant natural killer T cells promotes lipopolysaccharide-induced preterm birth.Opposition between PKC isoforms regulates histone deimination and neutrophil extracellular chromatin release.MicroRNAs in the regulation of immune response against infections.Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer.CHIP-mediated degradation of transglutaminase 2 negatively regulates tumor growth and angiogenesis in renal cancer.K33-linked polyubiquitination of Zap70 by Nrdp1 controls CD8(+) T cell activation.

P2860

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P2860

E3 ubiquitin ligase CHIP facilitates Toll-like receptor signaling by recruiting and polyubiquitinating Src and atypical PKC{zeta}.

http://www.wikidata.org/entity/Q35237506

description

2011 nî lūn-bûn

@nan

2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

E3 ubiquitin ligase CHIP facil ...... ng Src and atypical PKC{zeta}.

@ast

E3 ubiquitin ligase CHIP facil ...... ng Src and atypical PKC{zeta}.

@en

type

label

E3 ubiquitin ligase CHIP facil ...... ng Src and atypical PKC{zeta}.

@ast

E3 ubiquitin ligase CHIP facil ...... ng Src and atypical PKC{zeta}.

@en

prefLabel

E3 ubiquitin ligase CHIP facil ...... ng Src and atypical PKC{zeta}.

@ast

E3 ubiquitin ligase CHIP facil ...... ng Src and atypical PKC{zeta}.

@en

P1433

Q35237506-E8757DE6-E996-4C9F-8D62-F122E41DAD66

P1476

Q35237506-A6002FF6-E5B7-4DEA-AA98-8450B30CE7A0

P2093

Q35237506-1EFE5E56-0573-4756-8C58-FBD0BA086729

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Q35237506-C4709942-F319-461F-A448-0D53C7D87A99

Q35237506-CD920700-CAB4-4C78-A761-600556028D97

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P2860

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Q35237506-06B1E69E-0E8C-4277-9F4A-CA0205C4C7BB

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Q35237506-17B50A69-DBB7-4023-A761-44DD94F885C2

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Q35237506-28FAE645-CB55-4E69-93AB-63F0B518630F

Q35237506-2E57ED85-6B35-4F1F-A8A2-A6D352E89757

Q35237506-33641AA1-0249-4D03-9E17-BDB48C0FBF86

P304

Q35237506-BFBCEB7A-6893-4741-B869-2147572FDF2A

P31

Q35237506-D511383A-3134-42AF-834C-71855F341629

P356

Q35237506-FF09F176-1BE3-4D0F-9011-EB6939E7703D

P407

Q35237506-DFE43F12-89CE-41B9-B3C6-2505413F3523

P433

Q35237506-F06581D3-48A2-4D60-A4E2-053618141513

P478

Q35237506-9152C34F-6271-42BF-9B29-BE89EE23ADD4

P577

Q35237506-4827E712-24C5-4A67-9000-0F3D86238E59

P5875

Q35237506-C7944F40-E03F-469E-9B39-7CA647347884

P698

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P921

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P932

Q35237506-9994CB09-46F0-40DC-9CF7-E5CB91D53F5B

P356

P1433

Journal of Experimental Medicine

P1476

E3 ubiquitin ligase CHIP facil ...... ng Src and atypical PKC{zeta}.

@en

P2093

Chen Wang

http://www.w3.org/2001/XMLSchema#string

Liyun Shi

http://www.w3.org/2001/XMLSchema#string

Mingjin Yang

http://www.w3.org/2001/XMLSchema#string

Songqing Tang

http://www.w3.org/2001/XMLSchema#string

Taoyong Chen

http://www.w3.org/2001/XMLSchema#string

Xuetao Cao

http://www.w3.org/2001/XMLSchema#string

Xuhui Zhu

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions.

Protein kinase C zeta plays a central role in activation of the p42/44 mitogen-activated protein kinase by endotoxin in alveolar macrophages

The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins

CARDINAL, a novel caspase recruitment domain protein, is an inhibitor of multiple NF-kappa B activation pathways

Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex

Toll-like receptor 3 associates with c-Src tyrosine kinase on endosomes to initiate antiviral signaling

Involvement of TIRAP/MAL in signaling for the activation of interferon regulatory factor 3 by lipopolysaccharide

Small Rab GTPase Rab7b promotes megakaryocytic differentiation by enhancing IL-6 production and STAT3-GATA-1 association

Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta

NF-kappaB activator Act1 associates with IL-1/Toll pathway adaptor molecule TRAF6

P304

2099-2112

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1084/JEM.20102667

http://www.w3.org/2001/XMLSchema#string

P407

P433

10

http://www.w3.org/2001/XMLSchema#string

P478

208

http://www.w3.org/2001/XMLSchema#string

P577

2011-09-12T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51631781

http://www.w3.org/2001/XMLSchema#string

P698

21911421

http://www.w3.org/2001/XMLSchema#string

P921

Toll-like receptor

P932

3182058

http://www.w3.org/2001/XMLSchema#string