The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins
about
Upregulation of Hsp90-beta and annexin A1 correlates with poor survival and lymphatic metastasis in lung cancer patientsHsp90: a specialized but essential protein-folding toolThe tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulumAha1 binds to the middle domain of Hsp90, contributes to client protein activation, and stimulates the ATPase activity of the molecular chaperoneCHIP interacts with heat shock factor 1 during heat stressInteraction of Hsp90 with ribosomal proteins protects from ubiquitination and proteasome-dependent degradationCHIP controls the sensitivity of transforming growth factor-beta signaling by modulating the basal level of Smad3 through ubiquitin-mediated degradationHuman HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulumCytosolic quality control of mislocalized proteins requires RNF126 recruitment to Bag6Ubiquitylation of neuronal nitric-oxide synthase by CHIP, a chaperone-dependent E3 ligaseThe ataxia protein sacsin is a functional co-chaperone that protects against polyglutamine-expanded ataxin-1Structural and functional coupling of Hsp90- and Sgt1-centred multi-protein complexesEndoplasmic reticulum protein quality control is determined by cooperative interactions between Hsp/c70 protein and the CHIP E3 ligaseRecruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membraneCHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic responseCHIP participates in protein triage decisions by preferentially ubiquitinating Hsp70-bound substratesInteraction of the Hsp90 cochaperone cyclophilin 40 with Hsc70BAG-2 acts as an inhibitor of the chaperone-associated ubiquitin ligase CHIP.The cochaperone HspBP1 inhibits the CHIP ubiquitin ligase and stimulates the maturation of the cystic fibrosis transmembrane conductance regulatorSmall glutamine-rich protein/viral protein U-binding protein is a novel cochaperone that affects heat shock protein 70 activityHECT and RING finger families of E3 ubiquitin ligases at a glanceDocking-dependent ubiquitination of the interferon regulatory factor-1 tumor suppressor protein by the ubiquitin ligase CHIPDiversity of degradation signals in the ubiquitin-proteasome systemHsp70 chaperones: cellular functions and molecular mechanismRegulation of death-associated protein kinase. Stabilization by HSP90 heterocomplexesHistone deacetylase 8 safeguards the human ever-shorter telomeres 1B (hEST1B) protein from ubiquitin-mediated degradationThe cytoplasmic Hsp70 chaperone machinery subjects misfolded and endoplasmic reticulum import-incompetent proteins to degradation via the ubiquitin-proteasome systemHSP27 is a ubiquitin-binding protein involved in I-kappaBalpha proteasomal degradationDeath Associated Protein Kinase 1 (DAPK1): A Regulator of Apoptosis and AutophagyCHIP: A new modulator of human malignant disordersNovel endogenous angiogenesis inhibitors and their therapeutic potentialRecent advances in the molecular diagnostics of gastric cancerMaximizing the Therapeutic Potential of HSP90 InhibitorsDNAJs: more than substrate delivery to HSPASelective destruction of abnormal proteins by ubiquitin-mediated protein quality control degradationMolecular chaperones and co-chaperones in Parkinson diseaseMolecular chaperones in targeting misfolded proteins for ubiquitin-dependent degradationQuality control and fate determination of Hsp90 client proteinsTargeting Hsp90/Hsp70-based protein quality control for treatment of adult onset neurodegenerative diseasesHeat shock proteins at the crossroads between cancer and Alzheimer's disease
P2860
Q21198841-9BCF7A06-F191-4A59-9B1F-256ACC39A65FQ24291482-34758AB7-7F86-45CD-A209-CF5CA9C05015Q24291942-EC5C1D74-77E1-4244-AA69-9E85B0177995Q24295270-F67CBC74-92CF-48CB-9F56-682CBA246AE9Q24295301-D7BD3DF0-EC4F-4569-A533-BD7B87F132BAQ24297095-8489D355-9908-49EC-BD62-09E50F929D2CQ24298589-B370E7D1-023D-4A72-82AC-203B4EF06896Q24298901-068B60FC-F79A-46E0-ADA8-0098C743E925Q24300029-EBCC39C8-EFFC-4360-9B17-95C590836437Q24306256-58E67C7C-D6B3-420A-88FB-367D563D9BC4Q24310016-6ECCB455-1593-4522-807D-74D754234226Q24316241-562DC477-5117-454A-9AFE-060D55DBD100Q24320293-9157F24C-04AC-475F-AF7D-72DBA75DCE66Q24336904-B6BDC95D-B5BF-4E05-BADE-BE6D5DEA9F4AQ24336920-F6C1DB35-B052-4DBE-A635-6DEC6B983BBFQ24338386-5DCB55BB-980F-4EF6-AAE7-05ADCF84A155Q24520314-B0DCC817-7342-4744-A03E-3418AF3C6007Q24534836-D95FF90F-E793-49E6-B254-A0CF2E37D570Q24562651-17A3804A-847F-43F3-BE74-1EF5DABDC540Q24563260-E5A0F095-1AA9-4D8C-A43B-199CF241DFC3Q24599672-DFFE0391-BB99-4C02-BF10-69DB55BD0395Q24617588-C487284A-229E-4CCD-91EA-CF1FF338B435Q24642979-69D647E9-729D-4EBB-AAE7-33C74F6F9BABQ24644472-5F754108-D3D0-4362-A9F3-73094400A5F6Q24646541-6C83AB72-B32A-4A90-8B2F-0C3CD3547DD8Q24671304-5AB5FDF8-C336-4B3F-B06D-7323DA761B0DQ24676115-13EFAB79-720F-4D4B-ADFD-61E354047F0DQ24679412-B46A1FC2-BDCF-42D4-A942-A8FFB8E5C3E0Q26738428-B65C2B5A-AD80-4CF7-BB2F-00BE5815539DQ26752358-EEEF968D-98C7-4019-BAC9-0DFA4A884497Q26781297-5E6327EA-A066-4EEB-B82D-2858AB6F5C2AQ26785548-D520A714-7BDB-437E-8160-99BA3EB0722AQ26798318-2795E1BD-B6E2-4E00-B7D1-7DA020D8D9E0Q26801509-E2FDDBDB-B8FF-4054-BC38-D74A4B491F0EQ26824733-00820FD5-41E9-4178-B315-E87104384492Q26828834-F58F4D60-5E6F-4770-83DC-3ABFD42331A1Q26828990-7B0EC679-1DC8-4FA2-ADFF-2D05DB039F32Q26853052-7DA9B9B0-A7A5-4F27-BDE7-D4D99EC03DE3Q26859909-35B15968-2071-4878-AABF-DA89CF6F5BDAQ26864311-D044965C-BBC2-428F-AB23-955A146B72E8
P2860
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins
@ast
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins
@en
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins
@en-gb
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins
@nl
type
label
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins
@ast
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins
@en
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins
@en-gb
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins
@nl
prefLabel
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins
@ast
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins
@en
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins
@en-gb
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins
@nl
P2093
P921
P3181
P1433
P1476
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins
@en
P2093
C A Ballinger
C Patterson
L J Thompson
P3181
P356
10.1038/35050618
10.1038/35070170
P407
P577
2001-01-01T00:00:00Z
P6179
1013227263
1027958026