Dominant-negative mechanism of leukemogenic PAX5 fusions.
about
The leukemia-associated fusion protein MN1-TEL blocks TEL-specific recognition sequences.A conserved domain in the N-terminus is important for LEAFY dimerization and function in Arabidopsis thaliana.Pax5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia.B-lineage transcription factors and cooperating gene lesions required for leukemia development.PAX genes in childhood oncogenesis: developmental biology gone awry?BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint.Mechanisms of pre-B-cell receptor checkpoint control and its oncogenic subversion in acute lymphoblastic leukemia.Genomics in acute lymphoblastic leukaemia: insights and treatment implications.The pre-B-cell receptor checkpoint in acute lymphoblastic leukaemia.Molecular role of the PAX5-ETV6 oncoprotein in promoting B-cell acute lymphoblastic leukemia.PAX5-KIAA1549L: a novel fusion gene in a case of pediatric B-cell precursor acute lymphoblastic leukemia.Transcriptional suppression of BACH2 by the Bcr-Abl oncoprotein is mediated by PAX5.Dangerous fusions: a path to cancer for arrested lymphoid progenitors.Activating PAX gene family paralogs to complement PAX5 leukemia driver mutations
P2860
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P2860
Dominant-negative mechanism of leukemogenic PAX5 fusions.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Dominant-negative mechanism of leukemogenic PAX5 fusions.
@ast
Dominant-negative mechanism of leukemogenic PAX5 fusions.
@en
type
label
Dominant-negative mechanism of leukemogenic PAX5 fusions.
@ast
Dominant-negative mechanism of leukemogenic PAX5 fusions.
@en
prefLabel
Dominant-negative mechanism of leukemogenic PAX5 fusions.
@ast
Dominant-negative mechanism of leukemogenic PAX5 fusions.
@en
P2093
P2860
P356
P1433
P1476
Dominant-negative mechanism of leukemogenic PAX5 fusions.
@en
P2093
H P Koeffler
M A Pennella
N Kawamata
P2860
P2888
P304
P356
10.1038/ONC.2011.291
P407
P577
2011-07-18T00:00:00Z