Targeting diverse protein-protein interaction interfaces with α/β-peptides derived from the Z-domain scaffold.
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Effects of Single α-to-β Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic CrystallizationProtein-Protein Interactions Mediated by Helical Tertiary Structure Motifs.De Novo Modular Development of a Foldameric Protein-Protein Interaction Inhibitor for Separate Hot Spots: A Dynamic Covalent Assembly Approach.Folding and function in α/β-peptides: targets and therapeutic applications.Combined Use of Oligopeptides, Fragment Libraries, and Natural Compounds: A Comprehensive Approach To Sample the Druggability of Vascular Endothelial Growth Factor.Probing Protein Surfaces: QSAR Analysis with Helix Mimetics.Improving the Binding Affinity of in-Vitro-Evolved Cyclic Peptides by Inserting Atoms into the Macrocycle Backbone.High-resolution structures of a heterochiral coiled coilImpact of the amino acid sequence on the conformation of side chain lactam-bridged octapeptides.Comparison of design strategies for α-helix backbone modification in a protein tertiary fold.An optimal hydrogen-bond surrogate for α-helices.Systematic Targeting of Protein-Protein InteractionsTargeting recognition surfaces on natural proteins with peptidic foldamersIterative Nonproteinogenic Residue Incorporation Yields α/β-Peptides with a Helix-Loop-Helix Tertiary Structure and High Affinity for VEGF.Self-assembled vesicles of urea-tethered foldamers as hydrophobic drug carriers.Solution Observation of Dimerization and Helix Handedness Induction in a Human Carbonic Anhydrase-Helical Aromatic Amide Foldamer Complex.An Effective Strategy for Stabilizing Minimal Coiled Coil Mimetics.α/β-Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity in Living Cells.An α-Helix-Mimicking 12,13-Helix: Designed α/β/γ-Foldamers as Selective Inhibitors of Protein-Protein Interactions.Backbone Modification of a Parathyroid Hormone Receptor-1 Antagonist/Inverse AgonistDevelopment of Potent, Protease-Resistant Agonists of the Parathyroid Hormone Receptor with Broad β Residue Distribution.Targeting Unoccupied Surfaces on Protein-Protein Interfaces.Heterogeneous-Backbone Foldamer Mimics of Zinc Finger Tertiary Structure.Anion Recognition by Aliphatic Helical Oligoureas.Protein Domain Mimics as Modulators of Protein-Protein Interactions.Controlling the Helix Handedness of ααβ-Peptide Foldamers through Sequence Shifting.Foldamer Tertiary Structure through Sequence-Guided Protein Backbone Alteration.An α-Helix-Mimicking 12,13-Helix: Designed α/β/γ-Foldamers as Selective Inhibitors of Protein-Protein Interactions
P2860
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P2860
Targeting diverse protein-protein interaction interfaces with α/β-peptides derived from the Z-domain scaffold.
description
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2015 թուականի Մարտին հրատարակուած գիտական յօդուած
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2015 թվականի մարտին հրատարակված գիտական հոդված
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年论文
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name
Targeting diverse protein-prot ...... ed from the Z-domain scaffold.
@ast
Targeting diverse protein-prot ...... ed from the Z-domain scaffold.
@en
type
label
Targeting diverse protein-prot ...... ed from the Z-domain scaffold.
@ast
Targeting diverse protein-prot ...... ed from the Z-domain scaffold.
@en
prefLabel
Targeting diverse protein-prot ...... ed from the Z-domain scaffold.
@ast
Targeting diverse protein-prot ...... ed from the Z-domain scaffold.
@en
P2093
P2860
P356
P1476
Targeting diverse protein-prot ...... ed from the Z-domain scaffold.
@en
P2093
Dale F Kreitler
Katrina T Forest
Nicholas J Rettko
Nicole C Thomas
Samuel H Gellman
William L Murphy
P2860
P304
P356
10.1073/PNAS.1420380112
P407
P577
2015-03-30T00:00:00Z