Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations - Test2 - elhamkhani - TriplyDB

Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

http://www.wikidata.org/entity/Q35521811

about

Which New Health Technologies Do We Need to Achieve an End to HIV/AIDS?HIV-Host Interactions: Implications for Vaccine Design Humanized hemato-lymphoid system mice Role of HLA Adaptation in HIV Evolution Challenges and Opportunities for T-Cell-Mediated Strategies to Eliminate HIV Reservoirs Chimeric Antigen Receptor- and TCR-Modified T Cells Enter Main Street and Wall Street Enhancing Human Immunodeficiency Virus-Specific CD8(+) T Cell Responses with Heteroclitic Peptides Progress toward curing HIV infection with hematopoietic cell transplantation HIV-1 functional cure: will the dream come true?HIV therapeutic vaccines: moving towards a functional cure Structure and Dynamics of the Native HIV-1 Env Trimer Multi-dose Romidepsin Reactivates Replication Competent SIV in Post-antiretroviral Rhesus Macaque Controllers TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection Using animal models to overcome temporal, spatial and combinatorial challenges in HIV persistence research An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression Chemical Modification of Influenza CD8+ T-Cell Epitopes Enhances Their Immunogenicity Regardless of Immunodominance DNA/MVA Vaccination of HIV-1 Infected Participants with Viral Suppression on Antiretroviral Therapy, followed by Treatment Interruption: Elicitation of Immune Responses without Control of Re-Emergent Virus HIV Replication Is Not Controlled by CD8+ T Cells during the Acute Phase of the Infection in Humanized Mice Short-Sighted Virus Evolution and a Germline Hypothesis for Chronic Viral Infections.Recent Insights into the HIV/AIDS Pandemic.Barriers to HIV Cure.Latency reversal and viral clearance to cure HIV-1.A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes.A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques.Humoral and Innate Antiviral Immunity as Tools to Clear Persistent HIV Infection Similarity in viral and host promoters couples viral reactivation with host cell migration Advancements in Developing Strategies for Sterilizing and Functional HIV Cures.Human Immunodeficiency Virus Playing Hide-and-Seek: Understanding the TFH Cell Reservoir and Proposing Strategies to Overcome the Follicle Sanctuary The fate and lifespan of human monocyte subsets in steady state and systemic inflammation Double trouble: HIV latency and CTL escape Proof-of-Principle for Immune Control of Global HIV-1 Reactivation In Vivo.The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo Disease progression despite protective HLA expression in an HIV-infected transmission pair Broadening of Virus-Specific CD8+ T-Cell Responses Is Indicative of Residual Viral Replication in Aviremic SIV Controllers Targeting HIV Reservoir in Infected CD4 T Cells by Dual-Affinity Re-targeting Molecules (DARTs) that Bind HIV Envelope and Recruit Cytotoxic T Cells.Prolonged Antiretroviral Therapy Preserves HIV-1-Specific CD8 T Cells with Stem Cell-Like Properties Two-Year Follow-Up of Macaques Developing Intermittent Control of the Human Immunodeficiency Virus Homolog Simian Immunodeficiency Virus SIVmac251 in the Chronic Phase of Infection.A new hypothesis on HIV cure.Targeted HIV-1 Latency Reversal Using CRISPR/Cas9-Derived Transcriptional Activator Systems.Innate Immune Activity Correlates with CD4 T Cell-Associated HIV-1 DNA Decline during Latency-Reversing Treatment with Panobinostat.

P2860

Q26765043-E4849AE1-7C89-4568-9470-306ACF4603A6 Q26765966-209DB3E4-180E-40E0-B62B-6CE42AD248A7 Q26771440-7DEE683B-2B8F-4F4F-8D49-46B972B976AB Q26772713-805CA4BE-63EB-44FD-87E1-E674E2AFA0A9 Q26781511-B27B5F9E-060F-483D-8DB8-EA2E0D54FDA4 Q26799357-9DBCF706-DC78-462C-9750-B0CF2AB4FF89 Q26800123-BD98E1A6-5925-49A2-A649-197B642C348F Q26801269-1FE4E975-FC24-4583-B0D8-D41CA8719412 Q26865803-2DA550E2-9E0B-4A2E-A58A-ED4FD8F6ACB7 Q27002180-178B0F9B-9F3B-4592-9FF1-588A2DF32C37 Q27027570-B9810FAF-1D3B-4D2D-8A6E-1028C9ED2FD4 Q27312050-E526CFD6-FCA9-4B3C-8D2F-8813BCC4B28D Q27316403-51A308CD-E33D-4FB8-9CE7-AE95D13A5A98 Q28077662-E997FE7F-B9D9-461B-9E5F-F567C5251D4E Q28546918-0B8F71D3-46B4-474F-AB07-D4C30F9FF587 Q28552025-42A77591-8EE4-406A-BDAA-16E60C4C5E56 Q28554534-83A9C7B7-DA09-428D-AA1C-509FBEC8E5A8 Q28607258-AC9A2858-E093-4611-9FD5-24D449DCCFC1 Q30234948-EA11A2D1-9CE7-4E22-B575-72A76C2DD1BD Q30235024-931BACAF-6981-42E8-9CB3-F021D8815BED Q30245414-4CF3EE3D-25D5-4EEE-820F-701980ECA1C6 Q30248766-B5ACFEC1-BD7C-4CEF-B11A-1E6816C1F6BA Q30385378-50D6C2FD-7394-4893-97B5-46481FB859E8 Q30934059-61076238-5323-4632-8295-02575989D621 Q33620546-F997FD83-8108-40E6-89A0-B1AED1C22226 Q33640033-B8DB8A8C-A584-4BD6-9B02-3181FE6CCCAA Q33654409-A74F2E66-480D-4FE4-91FD-8041DAFECE99 Q33742139-DC1803C8-E0F9-46F4-A1A9-6250EA5831F2 Q33886544-BCD2B510-5372-4A0E-B324-E003D4FD0C90 Q35222625-A6C53273-A68A-4F98-BCFC-FA0E19C4AD06 Q35718251-265F0A67-8A91-44FE-842A-C48F4AACEDF7 Q35778783-9416F152-4604-4AF1-A408-4E79C6B520A4 Q35804078-AD285F1E-534E-45A5-9139-9DF37E8DD151 Q35831895-FDABF82F-D958-4723-A326-5DA8FA47BD35 Q35833324-CC87B6E7-517B-4AE3-9483-965CBA4B990A Q35861157-F485F32A-008E-4C6E-B76A-04858F466DC8 Q35861190-6E6F8687-5D9C-4502-962D-AB20814A1945 Q36028475-CCE2D5DA-878A-4AB7-9BF3-02D7F119B2B6 Q36060923-5EB90B43-BA94-4E5E-818D-9F4A7AB6A8F6 Q36086345-9EC2E711-E161-4562-B95B-17A126A1BA65

P2860

Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

http://www.wikidata.org/entity/Q35521811

description

2015 nî lūn-bûn

@nan

2015 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

name

Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

@ast

Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

@en

type

label

Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

@ast

Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

@en

prefLabel

Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

@ast

Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

@en

P1433

Q35521811-82114F61-2EBB-429C-8462-AB1C8EFC57B4

P1476

Q35521811-65F0EF9D-2506-410B-A736-461B5A833505

P2093

Q35521811-22DEC1D6-13D8-44B1-A7EE-F4A8D92EB80D

Q35521811-2BB9E36A-2E30-4E6B-A179-A75BFCFBBC29

Q35521811-326C0786-01A3-41A4-B934-BA36B3CAC522

Q35521811-37EC701B-784B-4E54-9A62-6694DF57D8A7

Q35521811-4A033890-0742-4F8E-AE0D-7EF5174455BA

Q35521811-5F1603CE-25FB-4060-A467-8AE3521EF73E

Q35521811-82D410A0-585B-4555-9B43-76173D70F8E9

Q35521811-85A8CE42-AF63-4C68-A0A5-6B62D8E9E151

Q35521811-978CAEFF-D8E8-434C-BEFB-EB055DF07EBC

Q35521811-9DBEF238-5C2A-4DDB-996E-57A933B76713

P2860

Q35521811-02394C97-7987-49AA-B4CA-EC090DF5C3A7

Q35521811-0326ACD9-B65E-4678-8D67-6CB857E17161

Q35521811-10CF86E7-2A4F-4E50-863A-3144D70AF7FB

Q35521811-251ED2D9-B1BF-454A-83A2-3A7E7F8AE6D6

Q35521811-2637FE23-453F-4551-B44C-04DFD2609A4B

Q35521811-29A57AA6-7399-4BE1-8D0C-BDC6613D3E22

Q35521811-2E90D100-ECB4-4613-86D2-B3CEE0BC5358

Q35521811-35F5B1A5-E115-446E-B9D1-D13B5B807C35

Q35521811-361694A6-7694-48D4-A610-2E4BB91CD637

Q35521811-36C06FF5-969E-4E85-9811-D6D52FBEEF57

P2888

Q35521811-4559346B-3339-4196-BEF1-3B7C1DEFE28A

P304

Q35521811-24DCEE67-5E1F-4458-9152-990104D10E95

P31

Q35521811-6CFCE6F5-527F-4909-B118-FC077807E439

P356

Q35521811-4EB4ADE9-AF3C-4A1D-AC41-938827838380

P407

Q35521811-E7D1A6A0-9700-4C56-A789-5FB3A05DC0EE

P433

Q35521811-D556BB1E-4C17-4DEF-9F67-F0F28B130ECE

P478

Q35521811-FC44BEDE-C647-4173-852F-012450166C3F

P50

Q35521811-0C3EBFCC-F5F9-4B6E-96AE-758169781E85

Q35521811-10DF7F9B-6D7D-4D01-B384-EF0A9CAA0638

Q35521811-18D1BB2D-E7A6-4909-9A23-BCAB939518FE

Q35521811-294D866E-E29D-4148-89A9-96E3DCD2AE73

Q35521811-2BE61F23-78BF-4D59-9847-20211E8BA913

Q35521811-31125572-D451-49BB-AB14-D482EC438D9F

Q35521811-41D14F47-1334-431E-9661-C326A4B6564D

Q35521811-64959A69-88E4-4608-8D49-7BA9BC64617C

Q35521811-B16DE175-73AD-4C4D-8D59-D5E5909A9849

Q35521811-DD98781C-9C8E-4162-B4E1-3F5D151877E0

P577

Q35521811-05DAF490-5A6E-4B8E-976D-3F33B3409CE3

P5875

Q35521811-D397E89E-1B39-49F4-974B-EEBD1E2A8799

P698

Q35521811-BD6032F0-73F3-44EA-9368-2362CB509CDA

P932

Q35521811-AF892576-09A7-4131-845E-82ECA606CCA2

P356

P1433

P1476

Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

@en

P2093

Anthony Rongvaux

http://www.w3.org/2001/XMLSchema#string

Cagan Gurer

http://www.w3.org/2001/XMLSchema#string

David M Valenzuela

http://www.w3.org/2001/XMLSchema#string

Gabriel Ghiaur

http://www.w3.org/2001/XMLSchema#string

George D Yancopoulos

http://www.w3.org/2001/XMLSchema#string

Hao Zhang

http://www.w3.org/2001/XMLSchema#string

Holly L McHugh

http://www.w3.org/2001/XMLSchema#string

Janet D Siliciano

http://www.w3.org/2001/XMLSchema#string

Jun Lai

http://www.w3.org/2001/XMLSchema#string

Leyao Wang

http://www.w3.org/2001/XMLSchema#string

P2860

Design and pre-clinical evaluation of a universal HIV-1 vaccine

Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid

Suberoylanilide hydroxamic acid reactivates HIV from latently infected cells

Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome

Fast gapped-read alignment with Bowtie 2

Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy

Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition

Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus

Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection

FLASH: fast length adjustment of short reads to improve genome assemblies

P2888

P304

381-385

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/NATURE14053

http://www.w3.org/2001/XMLSchema#string

P407

P433

7534

http://www.w3.org/2001/XMLSchema#string

P478

517

http://www.w3.org/2001/XMLSchema#string

P50

Richard Flavell

Andrew J Murphy

Christine M. Durand

Steven Salzberg

Robert F. Siliciano

P577

2015-01-07T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

270651704

http://www.w3.org/2001/XMLSchema#string

P698

25561180

http://www.w3.org/2001/XMLSchema#string

P932

4406054

http://www.w3.org/2001/XMLSchema#string