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Recognition of the bacterial second messenger cyclic diguanylate by its cognate riboswitchInvestigation of Mg2+- and temperature-dependent folding of the hairpin ribozyme by photo-crosslinking: effects of photo-crosslinker tether length and chemistryThe catalytic mechanism of hairpin ribozyme studied by hydrostatic pressure.Global analysis of riboswitches by small-angle X-ray scattering and calorimetryA comparison of vanadate to a 2'-5' linkage at the active site of a small ribozyme suggests a role for water in transition-state stabilizationStructural effects of nucleobase variations at key active site residue Ade38 in the hairpin ribozymeIdentification of an Imino Group Indispensable for Cleavage by a Small RibozymeThermodynamic analysis of ligand binding and ligand binding-induced tertiary structure formation by the thiamine pyrophosphate riboswitchAn in vitro evolved glmS ribozyme has the wild-type fold but loses coenzyme dependenceWater in the active site of an all-RNA hairpin ribozyme and effects of Gua8 base variants on the geometry of phosphoryl transferThe glmS ribozyme: use of a small molecule coenzyme by a gene-regulatory RNAUse of a coenzyme by the glmS ribozyme-riboswitch suggests primordial expansion of RNA chemistry by small moleculesUse of the spliceosomal protein U1A to facilitate crystallization and structure determination of complex RNAsThe glmS ribozyme tunes the catalytically critical pK(a) of its coenzyme glucosamine-6-phosphateCatalytic importance of a protonated adenosine in the hairpin ribozyme active siteRiboswitches: discovery of drugs that target bacterial gene-regulatory RNAs.Single-molecule enzymology of RNA: essential functional groups impact catalysis from a distanceModulation of quaternary structure and enhancement of ligand binding by the K-turn of tandem glycine riboswitches.Electrostatic interactions in the hairpin ribozyme account for the majority of the rate acceleration without chemical participation by nucleobasesIntermolecular domain docking in the hairpin ribozyme: metal dependence, binding kinetics and catalysisQuantum mechanical/molecular mechanical simulation study of the mechanism of hairpin ribozyme catalysisCobalt(III)hexaammine-dependent photocrosslinks in the hairpin ribozyme.Modulating RNA structure and catalysis: lessons from small cleaving ribozymes.Ribozymes and riboswitches: modulation of RNA function by small molecules.The many faces of the hairpin ribozyme: structural and functional variants of a small catalytic RNA.Nucleic acid catalysis: metals, nucleobases, and other cofactors.Engineering of ribozymes with useful activities in the ancient RNA world.Thermodynamics and kinetics of RNA tertiary structure formation in the junctionless hairpin ribozyme.A CA(+) pair adjacent to a sheared GA or AA pair stabilizes size-symmetric RNA internal loops.New approaches for cancer treatment: antitumor drugs based on gene-targeted nucleic acids.Characteristics of the glmS ribozyme suggest only structural roles for divalent metal ions.Structure-based insights into self-cleavage by a four-way junctional twister-sister ribozyme.Challenges and Perspectives in Nucleic Acid Enzyme Engineering.Structural Basis for Substrate Helix Remodeling and Cleavage Loop Activation in the Varkud Satellite Ribozyme.
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
The hairpin ribozyme.
@ast
The hairpin ribozyme.
@en
type
label
The hairpin ribozyme.
@ast
The hairpin ribozyme.
@en
prefLabel
The hairpin ribozyme.
@ast
The hairpin ribozyme.
@en
P2860
P356
P1433
P1476
The hairpin ribozyme.
@en
P2093
Adrian R Ferré-D'Amaré
P2860
P356
10.1002/BIP.10516
P577
2004-01-01T00:00:00Z