Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy
about
Rapalogs in cancer prevention: anti-aging or anticancer?GSK-3 as potential target for therapeutic intervention in cancerAdvances in targeting signal transduction pathwaysActivating ESR1 mutations in hormone-resistant metastatic breast cancer.Occupational exposure to carcinogens: Benzene, pesticides and fibers (Review)Occupational exposure to pesticides as a possible risk factor for the development of chronic diseases in humans (Review)Functional analysis of MKP-1 and MKP-2 in breast cancer tamoxifen sensitivityAnastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway.PI3K and mTOR signaling pathways in cancer: new data on targeted therapies.Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment.Hormone Therapy plus mTOR Inhibitors in the Treatment of Endometrial Carcinoma.Requirement for the eIF4E binding proteins for the synergistic down-regulation of protein synthesis by hypertonic conditions and mTOR inhibitionCooperative effects of Akt-1 and Raf-1 on the induction of cellular senescence in doxorubicin or tamoxifen treated breast cancer cells.Inhibition of Aerobic Glycolysis Represses Akt/mTOR/HIF-1α Axis and Restores Tamoxifen Sensitivity in Antiestrogen-Resistant Breast Cancer CellsThe role of S6K1 in ER-positive breast cancer.Harnessing the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia: eliminating activity by targeting at different levelsMechanisms of dihydrotestosterone action on resveratrol-induced anti-proliferation in breast cancer cells with different ERα status.Ectopic NGAL expression can alter sensitivity of breast cancer cells to EGFR, Bcl-2, CaM-K inhibitors and the plant natural product berberineAnswering the ultimate question "what is the proximal cause of aging?"Recent discoveries in the cycling, growing and aging of the p53 fieldMechanistic or mammalian target of rapamycin (mTOR) may determine robustness in young male mice at the cost of accelerated aging.Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response.Recent progress in genetics of aging, senescence and longevity: focusing on cancer-related genes.Common drugs and treatments for cancer and age-related diseases: revitalizing answers to NCI's provocative questions.Superior efficacy of co-treatment with dual PI3K/mTOR inhibitor NVP-BEZ235 and pan-histone deacetylase inhibitor against human pancreatic cancer.Inhibition of GSK-3β activity can result in drug and hormonal resistance and alter sensitivity to targeted therapy in MCF-7 breast cancer cells.Adipose-derived Mesenchymal Stem Cells (ASCs) may favour breast cancer recurrence via HGF/c-Met signaling.Endocrine resistance in breast cancer.Altholactone Inhibits NF-κB and STAT3 Activation and Induces Reactive Oxygen Species-Mediated Apoptosis in Prostate Cancer DU145 Cells.Integrin α5β1 simultaneously controls EGFR-dependent proliferation and Akt-dependent pro-survival signaling in epidermoid carcinoma cells.Midkine confers Adriamycin resistance in human gastric cancer cells.miR-202 Suppresses Cell Proliferation by Targeting FOXR2 in Endometrial Adenocarcinoma.The selective inhibition of nuclear PKCζ restores the effectiveness of chemotherapeutic agents in chemoresistant cells.In vitro assessment of antitumor activities of the PI3K/mTOR inhibitor GSK2126458.Targeting signaling and apoptotic pathways involved in chemotherapeutic drug-resistance of hematopoietic cells.Curcumin Suppresses the Colon Cancer Proliferation by Inhibiting Wnt/β-Catenin Pathways via miR-130a.Doxycycline inhibits breast cancer EMT and metastasis through PAR-1/NF-κB/miR-17/E-cadherin pathway.Virosecurinine induces apoptosis in human leukemia THP-1 cells and other underlying molecular mechanisms.A combination of curcumin and oligomeric proanthocyanidins offer superior anti-tumorigenic properties in colorectal cancer
P2860
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P2860
Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy
@ast
Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy
@en
type
label
Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy
@ast
Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy
@en
prefLabel
Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy
@ast
Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy
@en
P2093
P2860
P356
P1433
P1476
Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy
@en
P2093
Alberto M Martelli
Ferdinando Nicoletti
Franca Stivala
James A McCubrey
Kristin M Stadelman
Linda S Steelman
Lyudmyla B Drobot
Massimo Libra
Melissa L Sokolosky
Richard A Franklin
P2860
P304
P356
10.18632/ONCOTARGET.302
P407
P577
2011-07-01T00:00:00Z