Common drugs and treatments for cancer and age-related diseases: revitalizing answers to NCI's provocative questions.
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BRAF vs RAS oncogenes: are mutations of the same pathway equal? Differential signalling and therapeutic implicationsDiscovery of a Novel, Isothiazolonaphthoquinone-Based Small Molecule Activator of FOXO Nuclear-Cytoplasmic ShuttlingComputer-aided discovery of biological activity spectra for anti-aging and anti-cancer olive oil oleuropeins.Do metformin a real anticarcinogen? A critical reappraisal of experimental data.Minoxidil may suppress androgen receptor-related functionsOpioid receptor activation triggering downregulation of cAMP improves effectiveness of anti-cancer drugs in treatment of glioblastomaFrom rapalogs to anti-aging formula.Metformin limits the adipocyte tumor-promoting effect on ovarian cancer.Engineered ubiquitin ligase PTB-U-box targets insulin/insulin-like growth factor receptor for degradation and coordinately inhibits cancer malignancyClinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growthTOR-centric view on insulin resistance and diabetic complications: perspective for endocrinologists and gerontologists.Targeting nucleocytoplasmic transport in cancer therapyMetformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion currentThe broad-spectrum anti-DNA virus agent cidofovir inhibits lung metastasis of virus-independent, FGF2-driven tumors.Esophageal adenocarcinoma and obesity: peritumoral adipose tissue plays a role in lymph node invasion.Metformin-induced energy deficiency leads to the inhibition of lipogenesis in prostate cancer cells.Protein kinase C β inhibition by enzastaurin leads to mitotic missegregation and preferential cytotoxicity toward colorectal cancer cells with chromosomal instability (CIN)Comparison of rapamycin schedules in mice on high-fat diet.Rejuvenating immunity: "anti-aging drug today" eight years later.Circulating and tumor-infiltrating Tim-3 in patients with colorectal cancer.Leptin stimulates migration and invasion and maintains cancer stem-like properties in ovarian cancer cells: an explanation for poor outcomes in obese womenMetformin for cancer and aging prevention: is it a time to make the long story short?Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans.Polyphenolic drug composition based on benzenepolycarboxylic acids (BP-C3) increases life span and inhibits spontaneous tumorigenesis in female SHR mice.Metformin blocks progression of obesity-activated thyroid cancer in a mouse model.Metformin: do we finally have an anti-aging drug?Protease activated receptor-1 regulates macrophage-mediated cellular senescence: a risk for idiopathic pulmonary fibrosis.Bioinformatics Meets Biomedicine: OncoFinder, a Quantitative Approach for Interrogating Molecular Pathways Using Gene Expression Data.Gerometabolites: the pseudohypoxic aging side of cancer oncometabolites.Ubiquitous transgenic overexpression of C-C chemokine ligand 2: a model to assess the combined effect of high energy intake and continuous low-grade inflammation.Signaling pathways activation profiles make better markers of cancer than expression of individual genes.Immunosuppressants in cancer prevention and therapy
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P2860
Common drugs and treatments for cancer and age-related diseases: revitalizing answers to NCI's provocative questions.
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
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2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Common drugs and treatments fo ...... o NCI's provocative questions.
@en
type
label
Common drugs and treatments fo ...... o NCI's provocative questions.
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prefLabel
Common drugs and treatments fo ...... o NCI's provocative questions.
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P2860
P356
P1433
P1476
Common drugs and treatments fo ...... o NCI's provocative questions.
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P2860
P304
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10.18632/ONCOTARGET.890
P407
P577
2012-12-01T00:00:00Z