Mutant huntingtin, abnormal mitochondrial dynamics, defective axonal transport of mitochondria, and selective synaptic degeneration in Huntington's disease
about
Subcellular Clearance and Accumulation of Huntington Disease Protein: A Mini-ReviewIron dysregulation in Huntington's diseaseMitochondrial abnormalities in Alzheimer's disease: possible targets for therapeutic interventionAgeing and Parkinson's disease: why is advancing age the biggest risk factor?Inhibition of mitochondrial protein import by mutant huntingtinHuntingtin is required for normal excitatory synapse development in cortical and striatal circuitsRole of mtDNA haplogroups in the prevalence of osteoarthritis in different geographic populations: a meta-analysisImpaired import: how huntingtin harms.Role of mitochondrial homeostasis and dynamics in Alzheimer's disease.Dynamin-related protein 1 heterozygote knockout mice do not have synaptic and mitochondrial deficienciesImpaired GAPDH-induced mitophagy contributes to the pathology of Huntington's disease.Mitochondria-Targeted Antioxidant SS31 Prevents Amyloid Beta-Induced Mitochondrial Abnormalities and Synaptic Degeneration in Alzheimer's DiseaseDifferent molecular mechanisms involved in spontaneous and oxidative stress-induced mitochondrial fragmentation in tripeptidyl peptidase-1 (TPP-1)-deficient fibroblasts.Compartment-Dependent Degradation of Mutant Huntingtin Accounts for Its Preferential Accumulation in Neuronal ProcessesNutraceuticals against Neurodegeneration: A Mechanistic Insight.Mitochondria-targeted molecules MitoQ and SS31 reduce mutant huntingtin-induced mitochondrial toxicity and synaptic damage in Huntington's disease.A new method for quantifying mitochondrial axonal transport.Inhibition of mitochondrial fragmentation diminishes Huntington's disease-associated neurodegeneration.The Age of Cortical Neural Networks Affects Their Interactions with Magnetic Nanoparticles.Garrison Institute on Aging: A New Hope for Elderly Individuals and Patients with Alzheimer's Disease.Mechanisms underlying synaptic vulnerability and degeneration in neurodegenerative disease.Ataxin-3 and its e3 partners: implications for machado-joseph disease.Mitochondrial fusion proteins and human diseases.Mitochondrial dysfunctions in neurodegenerative diseases: relevance to Alzheimer's disease.Huntington's Disease: Pathogenic Mechanisms and Therapeutic Targets.A novel mitochondrial tRNA(Ala) gene variant causes chronic progressive external ophthalmoplegia in a patient with Huntington disease.Localized changes to glycogen synthase kinase-3 and collapsin response mediator protein-2 in the Huntington's disease affected brain.Mutant ubiquitin attenuates interleukin-1β- and tumor necrosis factor-α-induced pro-inflammatory signaling in human astrocytic cells.Huntington's Disease: Calcium Dyshomeostasis and Pathology ModelsCharacterization of axonal transport defects in Drosophila Huntingtin mutants.Both Orai1 and TRPC1 are Involved in Excessive Store-Operated Calcium Entry in Striatal Neurons Expressing Mutant Huntingtin Exon 1.Bar-coding neurodegeneration: identifying subcellular effects of human neurodegenerative disease proteins using Drosophila leg neurons.Soluble N-terminal fragment of mutant Huntingtin protein impairs mitochondrial axonal transport in cultured hippocampal neurons.Raft-like microdomains play a key role in mitochondrial impairment in lymphoid cells from patients with Huntington's disease.Protective Effects of Aqueous Extract of Luehea divaricata against Behavioral and Oxidative Changes Induced by 3-Nitropropionic Acid in Rats.Bcl-2/adenovirus E1B 19-kDa interacting protein (BNip3) has a key role in the mitochondrial dysfunction induced by mutant huntingtin.Prostaglandin E2 EP1 receptor antagonist improves motor deficits and rescues memory decline in R6/1 mouse model of Huntington's disease.VCP cooperates with UBXD1 to degrade mitochondrial outer membrane protein MCL1 in model of Huntington's disease.Topoisomerase 1 inhibitor topotecan delays the disease progression in a mouse model of Huntington's disease.Mitochondrial Metabolism in a Large-Animal Model of Huntington Disease: The Hunt for Biomarkers in the Spermatozoa of Presymptomatic Minipigs.
P2860
Q26752720-3AB4EF31-A943-414F-9F4C-4ED3DC563BC6Q26829932-F8E9463F-37FC-4E7E-B89D-DD00E2C64150Q26865358-BD0CD4F3-600A-4A89-BBB4-D862DFCA9C1FQ27021628-3F7DE3F8-DFEF-4BD3-B91A-8A585FC494EAQ28394803-363A6B24-9614-4BC2-8EBD-BC78EDB275A8Q30408636-8C75B20E-FE0E-45F6-A010-0355E5339096Q34395045-43358A43-D68A-478F-A7A2-02E2EC24FB09Q35664881-8C526E06-72B1-4DC6-BE1B-AEA1C0B08D59Q35916588-C9F5123B-70C4-4D83-A121-1B73F8342A9BQ35918643-2DC02B52-2365-4A0F-801E-83DA6CF1228EQ36159463-1FEE4A99-A39D-4ADB-832A-CAF8FD68ADB2Q36441971-2569AD53-DBC1-4C7E-B5A8-DD8CDA28DB9DQ36593242-077745B7-771D-4129-A4EE-C4112B55AF62Q37162698-F1ACF28D-F11F-435E-A8A8-79F7170C54E7Q37168739-850A1BBC-1EF8-41B2-ABFD-281D18196215Q37178581-ECCF0A1C-E4DF-400A-B1F2-69BD97570922Q37374220-EF48EABD-AE1E-4E6A-9763-F5A124A2A0F7Q37384081-9886815F-96C5-4FAF-8CF0-6AA69F59DEFCQ37634348-48C28FBC-F71D-4BA3-9FAB-AEA6E24424A9Q37690598-AC70911D-3D21-444B-8529-32511335AAC3Q38071648-FC9094E4-4422-470E-95C2-BB91FAEC7964Q38105068-9B333777-A66A-4AAF-AACB-82FC58C8628CQ38115530-9153626F-16ED-4196-897C-3EE108193765Q38217857-5A1C0A3B-075C-4339-AE91-ED08BF7BBB38Q38663090-498BDEFF-C063-440E-944F-6AFB4B2802DAQ38961648-24699386-71A8-44F0-A3C4-5BBF1F2E5135Q39014909-0F2CBCF0-94BF-4D69-B296-6439004F4B91Q39127443-A6297171-E4FD-4BC1-8223-F981ADDC6D96Q39456024-E42726B9-E24C-43EA-9329-1A1F22E443E5Q39679096-435F2603-B922-4838-A054-214ECECBF523Q40243449-3F3DD35E-0480-4ACA-829F-752890D50B6FQ41440551-02FAB869-8A94-4F99-AECE-2FA60E955A23Q41457916-A6E7265C-04D2-47C9-B050-2DF0DD7A6829Q41827082-BEBEC98D-3DFC-432F-A9AB-2C77A2C40AB5Q41841553-B66FFF1E-F718-4AC9-A4F5-00517D223FBEQ45289973-2ACBA24D-8150-42B6-9645-D4DDF2D8842BQ45295696-F6D86A8E-FD41-4CF4-B9A0-B86E42571F33Q45299293-1798A711-CB47-4A97-B272-402FFC4DC397Q45299733-EB8DAEDD-2D4D-4F91-9F60-5E03BE235320Q45302844-E3A47EC9-1443-412F-A55E-6AD655BAA2AF
P2860
Mutant huntingtin, abnormal mitochondrial dynamics, defective axonal transport of mitochondria, and selective synaptic degeneration in Huntington's disease
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Mutant huntingtin, abnormal mi ...... ration in Huntington's disease
@ast
Mutant huntingtin, abnormal mi ...... ration in Huntington's disease
@en
type
label
Mutant huntingtin, abnormal mi ...... ration in Huntington's disease
@ast
Mutant huntingtin, abnormal mi ...... ration in Huntington's disease
@en
prefLabel
Mutant huntingtin, abnormal mi ...... ration in Huntington's disease
@ast
Mutant huntingtin, abnormal mi ...... ration in Huntington's disease
@en
P2860
P1476
Mutant huntingtin, abnormal mi ...... ration in Huntington's disease
@en
P2093
P Hemachandra Reddy
Ulziibat P Shirendeb
P2860
P304
P356
10.1016/J.BBADIS.2011.10.016
P407
P577
2011-11-04T00:00:00Z