Association of Dnmt3a and thymine DNA glycosylase links DNA methylation with base-excision repair.
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Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repairThe current state of eukaryotic DNA base damage and repairDynamic DNA methylation in the brain: a new epigenetic mark for experience-dependent plasticityActive DNA demethylation of the vertebrate genomes by DNA methyltransferases: deaminase, dehydroxymethylase or demethylase?Crystal structure of human thymine DNA glycosylase bound to DNA elucidates sequence-specific mismatch recognitionStructural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residuesRole of base excision repair in maintaining the genetic and epigenetic integrity of CpG sitesMBD4 and TDG: multifaceted DNA glycosylases with ever expanding biological rolesEmbryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stabilityThe mutational spectrum of non-CpG DNA varies with CpG contentA TDG/CBP/RARĪ± ternary complex mediates the retinoic acid-dependent expression of DNA methylation-sensitive genesBase excision repair of tandem modifications in a methylated CpG dinucleotide.Active demethylation in mouse zygotes involves cytosine deamination and base excision repairSUMO-1 regulates the conformational dynamics of thymine-DNA Glycosylase regulatory domain and competes with its DNA binding activity.Using a medium-throughput comet assay to evaluate the global DNA methylation status of single cells.Active DNA demethylation: many roads lead to Rome.DNA methyltransferases, DNA damage repair, and cancerRecent advances in the structural mechanisms of DNA glycosylases5-Hydroxymethylcytosine: a stable or transient DNA modification?CpG methylation in neurons: message, memory, or mask?Atp6v0d2 is an essential component of the osteoclast-specific proton pump that mediates extracellular acidification in bone resorption.Active DNA demethylation mediated by DNA glycosylases.Regulation and function of DNA methylation in plants and animals.A comprehensive analysis of radiosensitization targets; functional inhibition of DNA methyltransferase 3B radiosensitizes by disrupting DNA damage regulation.DNA methylation patterns of candidate genes regulated by thymine DNA glycosylase in patients with TP53 germline mutations.Mutations in DNA methyltransferase (DNMT3A) observed in acute myeloid leukemia patients disrupt processive methylationMultifaceted roles for thymine DNA glycosylase in embryonic development and human carcinogenesisTranscriptional regulation of thymine DNA glycosylase (TDG) by the tumor suppressor protein p53Base excision repair, aging and health span.Activation-induced cytidine deaminase (AID) is necessary for the epithelial-mesenchymal transition in mammary epithelial cells.Ten-eleven translocation (Tet) and thymine DNA glycosylase (TDG), components of the demethylation pathway, are direct targets of miRNA-29aDNA demethylation by TDG.5-hydroxymethylcytosine: a potential therapeutic target in cancer.Characterization of Dnmt3b:thymine-DNA glycosylase interaction and stimulation of thymine glycosylase-mediated repair by DNA methyltransferase(s) and RNA.DNA methylation: dynamic and stable regulation of memory.Driver mutations of cancer epigenomes.BERing the burden of damage: Pathway crosstalk and posttranslational modification of base excision repair proteins regulate DNA damage management.Epigenetic Mechanisms as an Interface Between the Environment and Genome.Domain Structure of the Dnmt1, Dnmt3a, and Dnmt3b DNA Methyltransferases.A sensitive, homogeneous fluorescence assay for detection of thymine DNA glycosylase activity based on exonuclease-mediated amplification.
P2860
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P2860
Association of Dnmt3a and thymine DNA glycosylase links DNA methylation with base-excision repair.
description
2006 nĆ® lÅ«n-bĆ»n
@nan
2006幓ć®č«ę
@ja
2006幓č«ę
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2006幓č«ę
@zh-hant
2006幓č«ę
@zh-hk
2006幓č«ę
@zh-mo
2006幓č«ę
@zh-tw
2006幓č®ŗę
@wuu
2006幓č®ŗę
@zh
2006幓č®ŗę
@zh-cn
name
Association of Dnmt3a and thym ...... ion with base-excision repair.
@ast
Association of Dnmt3a and thym ...... ion with base-excision repair.
@en
type
label
Association of Dnmt3a and thym ...... ion with base-excision repair.
@ast
Association of Dnmt3a and thym ...... ion with base-excision repair.
@en
prefLabel
Association of Dnmt3a and thym ...... ion with base-excision repair.
@ast
Association of Dnmt3a and thym ...... ion with base-excision repair.
@en
P2093
P2860
P356
P1476
Association of Dnmt3a and thym ...... tion with base-excision repair
@en
P2093
Guo-Liang Xu
Ping-Zhu Zhou
Xiu-Dan Zheng
Ya-Qiang Li
P2860
P304
P356
10.1093/NAR/GKL1052
P407
P50
P577
2006-12-14T00:00:00Z