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Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative actionRNA-mediated pathogenic mechanisms in polyglutamine diseases and amyotrophic lateral sclerosisInteraction between RAX and PKR modulates the effect of ethanol on protein synthesis and survival of neuronsSatratoxin G-induced apoptosis in PC-12 neuronal cells is mediated by PKR and caspase independentThe chemotherapeutic drug 5-fluorouracil promotes PKR-mediated apoptosis in a p53-independent manner in colon and breast cancer cellsActivation of double-stranded RNA-activated protein kinase by mild impairment of oxidative metabolism in neuronsInteraction of double-stranded RNA-dependent protein kinase (PKR) with the death receptor signaling pathway in amyloid beta (Abeta)-treated cells and in APPSLPS1 knock-in miceActivation of PKR causes amyloid ß-peptide accumulation via de-repression of BACE1 expression.Inhibition of host translation by virus infection in vivo.Ethanol promotes thiamine deficiency-induced neuronal death: involvement of double-stranded RNA-activated protein kinase.Viral dsRNA inhibitors prevent self-association and autophosphorylation of PKR.PKR, the double stranded RNA-dependent protein kinase as a critical target in Alzheimer's diseaseThe Specific Protein Kinase R (PKR) Inhibitor C16 Protects Neonatal Hypoxia-Ischemia Brain Damages by Inhibiting Neuroinflammation in a Neonatal Rat Model.Up-Regulation of PKR Signaling Pathway by Ethanol Displays an Age of Onset-Dependent Relationship.Essential role of PACT-mediated PKR activation in tunicamycin-induced apoptosis.Mapping of the auto-inhibitory interactions of protein kinase R by nuclear magnetic resonance.Altered Co-Translational Processing Plays a Role in Huntington's Pathogenesis-A Hypothesis.Phosphorylation of the alpha subunit of translation initiation factor-2 by PKR mediates protein synthesis inhibition in the mouse brain during status epilepticus.PKR involvement in Alzheimer's diseasePrevention of the β-amyloid peptide-induced inflammatory process by inhibition of double-stranded RNA-dependent protein kinase in primary murine mixed co-cultures.A role for PKR in hematologic malignancies.PKR, a cognitive decline biomarker, can regulate translation via two consecutive molecular targets p53 and Redd1 in lymphocytes of AD patients.Molecular framework for the activation of RNA-dependent protein kinase.Activated mTOR and PKR kinases in lymphocytes correlate with memory and cognitive decline in Alzheimer's disease.Epstein-Barr and other viral mimicry of autoantigens, myelin and vitamin D-related proteins and of EIF2B, the cause of vanishing white matter disease: massive mimicry of multiple sclerosis relevant proteins by the Synechococcus phage.
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
PKR activation in neurodegenerative disease.
@ast
PKR activation in neurodegenerative disease.
@en
type
label
PKR activation in neurodegenerative disease.
@ast
PKR activation in neurodegenerative disease.
@en
prefLabel
PKR activation in neurodegenerative disease.
@ast
PKR activation in neurodegenerative disease.
@en
P2860
P356
P1476
PKR activation in neurodegenerative disease.
@en
P2093
Alyson L Peel
P2860
P304
P356
10.1093/JNEN/63.2.97
P577
2004-02-01T00:00:00Z