Distinct p53 genomic binding patterns in normal and cancer-derived human cells. - Test2 - elhamkhani - TriplyDB

Distinct p53 genomic binding patterns in normal and cancer-derived human cells.

Distinct p53 genomic binding patterns in normal and cancer-derived human cells.

http://www.wikidata.org/entity/Q35737507

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The transcription factor p53: not a repressor, solely an activator Changes in human pluripotent stem cell gene expression after genotoxic stress exposures A p53 drug response signature identifies prognostic genes in high-risk neuroblastoma Cistrome plasticity and mechanisms of cistrome reprogramming Condition-specific target prediction from motifs and expression.Large-scale quality analysis of published ChIP-seq data.Microarray and ChIP-seq data analysis revealed changes in p53-mediated transcriptional regulation in Nutlin-3-treated U2OS cells A polymorphic p53 response element in KIT ligand influences cancer risk and has undergone natural selection.A PTCH1 homolog transcriptionally activated by p53 suppresses Hedgehog signaling Cell context dependent p53 genome-wide binding patterns and enrichment at repeats.Structure-based predictions broadly link transcription factor mutations to gene expression changes in cancers.p53 and cell cycle dependent transcription of kinesin family member 23 (KIF23) is controlled via a CHR promoter element bound by DREAM and MMB complexes.p53 binding to human genome: crowd control navigation in chromatin context Interactions of chromatin context, binding site sequence content, and sequence evolution in stress-induced p53 occupancy and transactivation.Unraveling regulatory programs for NF-kappaB, p53 and microRNAs in head and neck squamous cell carcinoma.Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53 Mutant p53 cooperates with ETS2 to promote etoposide resistance.Comprehensive Expression Profiling and Functional Network Analysis of p53-Regulated MicroRNAs in HepG2 Cells Treated with Doxorubicin The common stress responsive transcription factor ATF3 binds genomic sites enriched with p300 and H3K27ac for transcriptional regulation.p53-Regulated Networks of Protein, mRNA, miRNA, and lncRNA Expression Revealed by Integrated Pulsed Stable Isotope Labeling With Amino Acids in Cell Culture (pSILAC) and Next Generation Sequencing (NGS) Analyses Genome-wide analysis of p63 binding sites identifies AP-2 factors as co-regulators of epidermal differentiation p53 regulates the mevalonate pathway in human glioblastoma multiforme.Radiation-induced alternative transcription and splicing events and their applicability to practical biodosimetry Recent discoveries in the cycling, growing and aging of the p53 field Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses.Dachshund binds p53 to block the growth of lung adenocarcinoma cells Negative control of CSL gene transcription by stress/DNA damage response and p53.Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells.Integration of TP53, DREAM, MMB-FOXM1 and RB-E2F target gene analyses identifies cell cycle gene regulatory networks.Local depletion of DNA methylation identifies a repressive p53 regulatory region in the NEK2 promoter.Genome-wide profiling reveals stimulus-specific functions of p53 during differentiation and DNA damage of human embryonic stem cells Rotational positioning of nucleosomes facilitates selective binding of p53 to response elements associated with cell cycle arrest.Transcriptional and post-transcriptional regulation of the ionizing radiation response by ATM and p53 NRF2 and p53: Januses in cancer?Indirect p53-dependent transcriptional repression of Survivin, CDC25C, and PLK1 genes requires the cyclin-dependent kinase inhibitor p21/CDKN1A and CDE/CHR promoter sites binding the DREAM complex.Neat1 is a p53-inducible lincRNA essential for transformation suppression.Tumorigenesis by Meis1 overexpression is accompanied by a change of DNA target-sequence specificity which allows binding to the AP-1 element p53-dependent non-coding RNA networks in chronic lymphocytic leukemia.Parallel profiling of the transcriptome, cistrome, and epigenome in the cellular response to ionizing radiation.Polo-like kinase 4 transcription is activated via CRE and NRF1 elements, repressed by DREAM through CDE/CHR sites and deregulated by HPV E7 protein.

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P2860

Distinct p53 genomic binding patterns in normal and cancer-derived human cells.

http://www.wikidata.org/entity/Q35737507

description

2011 nî lūn-bûn

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2011年の論文

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2011年论文

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2011年论文

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2011年论文

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name

Distinct p53 genomic binding patterns in normal and cancer-derived human cells.

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Distinct p53 genomic binding patterns in normal and cancer-derived human cells.

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type

label

Distinct p53 genomic binding patterns in normal and cancer-derived human cells.

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Distinct p53 genomic binding patterns in normal and cancer-derived human cells.

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prefLabel

Distinct p53 genomic binding patterns in normal and cancer-derived human cells.

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Distinct p53 genomic binding patterns in normal and cancer-derived human cells.

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Distinct p53 genomic binding patterns in normal and cancer-derived human cells.

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John J Dunn

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Krassimira Botcheva

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Sean R McCorkle

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P2860

Critical DNA binding interactions of the insulator protein CTCF: a small number of zinc fingers mediate strong binding, and a single finger-DNA interaction controls binding at imprinted loci

A highly conserved proapoptotic gene, IKIP, located next to the APAF1 gene locus, is regulated by p53

An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles

Possible existence of lysosome-like organella within mitochondria and its role in mitochondrial quality control

Identification of the mismatch repair genes PMS2 and MLH1 as p53 target genes by using serial analysis of binding elements

Direct visualization of the co-transcriptional assembly of a nuclear body by noncoding RNAs

Human DNA methylomes at base resolution show widespread epigenomic differences

The first 30 years of p53: growing ever more complex

Altered nuclear retention of mRNAs containing inverted repeats in human embryonic stem cells: functional role of a nuclear noncoding RNA

Cytoplasmic foci are sites of mRNA decay in human cells

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W. Richard McCombie

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