Challenges for the development of ribonucleoside analogues as inducers of error catastrophe.
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Selection for robustness in mutagenized RNA virusesTopology of evolving, mutagenized viral populations: quasispecies expansion, compression, and operation of negative selection.Synthesis of a 6-methyl-7-deaza analogue of adenosine that potently inhibits replication of polio and dengue virusesExamining the theory of error catastrophe.5-Azacytidine can induce lethal mutagenesis in human immunodeficiency virus type 1.Molecular dynamics simulations of viral RNA polymerases link conserved and correlated motions of functional elements to fidelityHepatitis C virus and the immune system: a concise review.Lethal mutagenesis of poliovirus mediated by a mutagenic pyrimidine analogue.Synthesis and antiviral activity of 5-substituted cytidine analogues: identification of a potent inhibitor of viral RNA-dependent RNA polymerases.Lethal mutagenesis of picornaviruses with N-6-modified purine nucleoside analogues.Discovery of novel ribonucleoside analogs with activity against human immunodeficiency virus type 1Therapeutically targeting RNA viruses via lethal mutagenesis.Foot-and-mouth disease virus mutant with decreased sensitivity to ribavirin: implications for error catastrophe.Mutagenesis-induced, large fitness variations with an invariant arenavirus consensus genomic nucleotide sequence.Determinants of RNA-dependent RNA polymerase (in)fidelity revealed by kinetic analysis of the polymerase encoded by a foot-and-mouth disease virus mutant with reduced sensitivity to ribavirin.Theory of lethal mutagenesis for viruses.Biochemical characterization of the fidelity of poliovirus RNA-dependent RNA polymerase.Future prospects for the treatment of rapidly evolving viral pathogens: insights from evolutionary biology
P2860
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P2860
Challenges for the development of ribonucleoside analogues as inducers of error catastrophe.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Challenges for the development ...... inducers of error catastrophe.
@ast
Challenges for the development ...... inducers of error catastrophe.
@en
type
label
Challenges for the development ...... inducers of error catastrophe.
@ast
Challenges for the development ...... inducers of error catastrophe.
@en
prefLabel
Challenges for the development ...... inducers of error catastrophe.
@ast
Challenges for the development ...... inducers of error catastrophe.
@en
P2860
P1476
Challenges for the development ...... inducers of error catastrophe.
@en
P2093
Jason D Graci
P2860
P356
10.1177/095632020401500101
P577
2004-01-01T00:00:00Z