Differing conformational pathways before and after chemistry for insertion of dATP versus dCTP opposite 8-oxoG in DNA polymerase beta
about
DNA polymerase family X: function, structure, and cellular rolesDNA polymerase minor groove interactions modulate mutagenic bypass of a templating 8-oxoguanine lesionOxidant and environmental toxicant-induced effects compromise DNA ligation during base excision DNA repairDistinct energetics and closing pathways for DNA polymerase beta with 8-oxoG template and different incoming nucleotides.Effect of oxidatively damaged DNA on the active site preorganization during nucleotide incorporation in a high fidelity polymerase from Bacillus stearothermophilus."Gate-keeper" residues and active-site rearrangements in DNA polymerase μ help discriminate non-cognate nucleotides.Molecular dynamics simulations of double-stranded DNA in an explicit solvent model with the zero-dipole summation method.The DNA polymerase gamma Y955C disease variant associated with PEO and parkinsonism mediates the incorporation and translesion synthesis opposite 7,8-dihydro-8-oxo-2'-deoxyguanosine.Reprint of "Oxidant and environmental toxicant-induced effects compromise DNA ligation during base excision DNA repair".Perspective: pre-chemistry conformational changes in DNA polymerase mechanismsInsertion of oxidized nucleotide triggers rapid DNA polymerase openingHow DNA polymerase X preferentially accommodates incoming dATP opposite 8-oxoguanine on the template.Catalytic effects of mutations of distant protein residues in human DNA polymerase β: theory and experiment.Mismatched base-pair simulations for ASFV Pol X/DNA complexes help interpret frequent G*G misincorporation.
P2860
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P2860
Differing conformational pathways before and after chemistry for insertion of dATP versus dCTP opposite 8-oxoG in DNA polymerase beta
description
2007 nî lūn-bûn
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2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Differing conformational pathw ...... 8-oxoG in DNA polymerase beta
@ast
Differing conformational pathw ...... 8-oxoG in DNA polymerase beta
@en
type
label
Differing conformational pathw ...... 8-oxoG in DNA polymerase beta
@ast
Differing conformational pathw ...... 8-oxoG in DNA polymerase beta
@en
prefLabel
Differing conformational pathw ...... 8-oxoG in DNA polymerase beta
@ast
Differing conformational pathw ...... 8-oxoG in DNA polymerase beta
@en
P2093
P2860
P1433
P1476
Differing conformational pathw ...... 8-oxoG in DNA polymerase beta
@en
P2093
Sujatha Reddy
Tamar Schlick
William A Beard
Yanli Wang
P2860
P304
P356
10.1529/BIOPHYSJ.106.092106
P407
P577
2007-02-09T00:00:00Z