Resistance to HSV-1 infection in the epithelium resides with the novel innate sensor, IFI-16
about
Intrinsic host restriction factors of human cytomegalovirus replication and mechanisms of viral escapeThe role of dendritic cells in immunity against primary herpes simplex virus infectionsRecognition of cytosolic DNA by cGAS and other STING-dependent sensorsImmunological aspects of acute and recurrent herpes simplex keratitisThe inflammasome as a target of modulation by DNA virusesHerpes Simplex Virus and Interferon Signaling Induce Novel Autophagic Clusters in Sensory NeuronsMicroglia-induced IL-6 protects against neuronal loss following HSV-1 infection of neural progenitor cells.Interferon γ-inducible protein (IFI) 16 transcriptionally regulates type i interferons and other interferon-stimulated genes and controls the interferon response to both DNA and RNA virusesHerpes keratitis.Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 proteinA STING-dependent innate-sensing pathway mediates resistance to corneal HSV-1 infection via upregulation of the antiviral effector tetherinA Highly Efficacious Herpes Simplex Virus 1 Vaccine Blocks Viral Pathogenesis and Prevents Corneal Immunopathology via Humoral ImmunityInterleukin-1α released from HSV-1-infected keratinocytes acts as a functional alarmin in the skin.Degeneration and regeneration of corneal nerves in response to HSV-1 infectionEvasion of early antiviral responses by herpes simplex viruses.Nuclear sensing of viral DNA, epigenetic regulation of herpes simplex virus infection, and innate immunityThe Current State of Vaccine Development for Ocular HSV-1 InfectionGranulocytes in Ocular HSV-1 Infection: Opposing Roles of Mast Cells and NeutrophilsDistinct Upstream Role of Type I IFN Signaling in Hematopoietic Stem Cell-Derived and Epithelial Resident Cells for Concerted Recruitment of Ly-6Chi Monocytes and NK Cells via CCL2-CCL3 CascadeRole of the DNA Sensor STING in Protection from Lethal Infection following Corneal and Intracerebral Challenge with Herpes Simplex Virus 1.IFN-α-driven CCL2 production recruits inflammatory monocytes to infection site in mice.The molecular mechanism of breast cancer cell apoptosis induction by absent in melanoma (AIM2)Targeting the genital tract mucosa with a lipopeptide/recombinant adenovirus prime/boost vaccine induces potent and long-lasting CD8+ T cell immunity against herpes: importance of MyD88.Microglia and a functional type I IFN pathway are required to counter HSV-1-driven brain lateral ventricle enlargement and encephalitisLearning from the messengers: innate sensing of viruses and cytokine regulation of immunity - clues for treatments and vaccines.Synergistic control of herpes simplex virus pathogenesis by IRF-3, and IRF-7 revealed through non-invasive bioluminescence imaging.Immunological control of herpes simplex virus infections.HSV-1 targets lymphatic vessels in the eye and draining lymph node of mice leading to edema in the absence of a functional type I interferon response.Generating protective immunity against genital herpesRecognition of herpes simplex viruses: toll-like receptors and beyondIFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes.Type I interferons in regulation of mucosal immunity.DNA recognition in immunity and disease.Molecular basis of DNA recognition in the immune system.Type I interferon and lymphangiogenesis in the HSV-1 infected cornea - are they beneficial to the host?Cellular sensing of viral DNA and viral evasion mechanisms.Animal models of herpes simplex virus immunity and pathogenesis.Evasion of the STING DNA-Sensing Pathway by VP11/12 of Herpes Simplex Virus 1.Impaired STING Pathway in Human Osteosarcoma U2OS Cells Contributes to the Growth of ICP0-Null Mutant Herpes Simplex Virus.Impact of Type I Interferon on the Safety and Immunogenicity of an Experimental Live-Attenuated Herpes Simplex Virus 1 Vaccine in Mice.
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P2860
Resistance to HSV-1 infection in the epithelium resides with the novel innate sensor, IFI-16
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Resistance to HSV-1 infection ...... he novel innate sensor, IFI-16
@ast
Resistance to HSV-1 infection ...... he novel innate sensor, IFI-16
@en
type
label
Resistance to HSV-1 infection ...... he novel innate sensor, IFI-16
@ast
Resistance to HSV-1 infection ...... he novel innate sensor, IFI-16
@en
prefLabel
Resistance to HSV-1 infection ...... he novel innate sensor, IFI-16
@ast
Resistance to HSV-1 infection ...... he novel innate sensor, IFI-16
@en
P2093
P2860
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Resistance to HSV-1 infection ...... he novel innate sensor, IFI-16
@en
P2093
C D Conrady
D J J Carr
K A Fitzgerald
P2860
P2888
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P356
10.1038/MI.2011.63
P50
P577
2012-01-11T00:00:00Z