Structural and Functional Analysis of the GADD34:PP1 eIF2α Phosphatase.
about
Inadequate fine-tuning of protein synthesis and failure of amino acid homeostasis following inhibition of the ATPase VCP/p97Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2α-mediated stress signalingMolecular Insights into the Fungus-Specific Serine/Threonine Protein Phosphatase Z1 in Candida albicansMouse Rif1 is a regulatory subunit of protein phosphatase 1 (PP1).Profiling the MAPK/ERK dependent and independent activity regulated transcriptional programs in the murine hippocampus in vivo.PPP1R15A-mediated dephosphorylation of eIF2α is unaffected by Sephin1 or Guanabenz.α-Asarone blocks 7β-hydroxycholesterol-exposed macrophage injury through blocking elF2α phosphorylation and prompting beclin-1-dependent autophagyGADD34 Function in Protein Trafficking Promotes Adaptation to Hyperosmotic Stress in Human Corneal Cells.Chronic oxidative stress promotes GADD34-mediated phosphorylation of the TAR DNA-binding protein TDP-43, a modification linked to neurodegeneration.eIF2α phosphorylation is pathognomonic for immunogenic cell death.Oxidative stress promotes SIRT1 recruitment to the GADD34/PP1α complex to activate its deacetylase function.Role of the unfolded protein response in determining the fate of tumor cells and the promise of multi-targeted therapies.Decoding the selectivity of eIF2α holophosphatases and PPP1R15A inhibitors.A Sephin1-insensitive tripartite holophosphatase dephosphorylates translation initiation factor 2α.ZIKV infection activates the IRE1-XBP1 and ATF6 pathways of unfolded protein response in neural cells
P2860
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P2860
Structural and Functional Analysis of the GADD34:PP1 eIF2α Phosphatase.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Structural and Functional Analysis of the GADD34:PP1 eIF2α Phosphatase.
@ast
Structural and Functional Analysis of the GADD34:PP1 eIF2α Phosphatase.
@en
type
label
Structural and Functional Analysis of the GADD34:PP1 eIF2α Phosphatase.
@ast
Structural and Functional Analysis of the GADD34:PP1 eIF2α Phosphatase.
@en
prefLabel
Structural and Functional Analysis of the GADD34:PP1 eIF2α Phosphatase.
@ast
Structural and Functional Analysis of the GADD34:PP1 eIF2α Phosphatase.
@en
P2093
P2860
P1433
P1476
Structural and Functional Analysis of the GADD34:PP1 eIF2α Phosphatase.
@en
P2093
Catherine W Goh
Irene C Lee
Jocelyn C Newton
Permeen Yusoff
Rebecca Page
Shirish Shenolikar
Wolfgang Peti
P2860
P304
P356
10.1016/J.CELREP.2015.05.043
P50
P577
2015-06-18T00:00:00Z