Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites - Test2 - elhamkhani - TriplyDB

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

http://www.wikidata.org/entity/Q24304144

about

Phosphatases of α-synuclein, LRRK2, and tau: important players in the phosphorylation-dependent pathology of Parkinsonism Protein phosphatases and Alzheimer's disease Counteracting Protein Kinase Activity in the Heart: The Multiple Roles of Protein Phosphatases Asparaginase treatment side-effects may be due to genes with homopolymeric Asn codons (Review-Hypothesis)Intrinsic Order and Disorder in the Bcl-2 Member Harakiri: Insights into Its Proapoptotic Activity The Molecular Basis for Substrate Specificity of the Nuclear NIPP1:PP1 Holoenzyme Development of a Peptide that Selectively Activates Protein Phosphatase-1 in Living Cells The Molecular Mechanism of Substrate Engagement and Immunosuppressant Inhibition of Calcineurin Structure of the Ca2+-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code Plasmodium falciparum inhibitor-3 homolog increases protein phosphatase type 1 activity and is essential for parasitic survival Small molecules targeted to a non-catalytic "RVxF" binding site of protein phosphatase-1 inhibit HIV-1 Molecular mechanisms underlying the interaction of protein phosphatase-1c with ASPP proteins.Identification of a Plasmodium falciparum inhibitor-2 motif involved in the binding and regulation activity of protein phosphatase type 1 Protein Ser/Thr phosphatases--the ugly ducklings of cell signalling.Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction.Structural diversity in free and bound states of intrinsically disordered protein phosphatase 1 regulators.Age-dependent targeting of protein phosphatase 1 to Ca2+/calmodulin-dependent protein kinase II by spinophilin in mouse striatum.Flexibility in the PP1:spinophilin holoenzyme Molecular investigations of the structure and function of the protein phosphatase 1-spinophilin-inhibitor 2 heterotrimeric complex Identification of AKAP79 as a protein phosphatase 1 catalytic binding protein The extended PP1 toolkit: designed to create specificity.Viewing serine/threonine protein phosphatases through the eyes of drug designers Beyond the dopamine receptor: regulation and roles of serine/threonine protein phosphatases.Actin dynamics tune the integrated stress response by regulating eukaryotic initiation factor 2α dephosphorylation.G-actin provides substrate-specificity to eukaryotic initiation factor 2α holophosphatases.Dissociation of SHP-1 from spinophilin during platelet activation exposes an inhibitory binding site for protein phosphatase-1 (PP1)Reg1 protein regulates phosphorylation of all three Snf1 isoforms but preferentially associates with the Gal83 isoform Microtubule binding by KNL-1 contributes to spindle checkpoint silencing at the kinetochore.Structural and Functional Analysis of the GADD34:PP1 eIF2α Phosphatase.An eIF2α-binding motif in protein phosphatase 1 subunit GADD34 and its viral orthologs is required to promote dephosphorylation of eIF2α.Structural basis for protein phosphatase 1 regulation and specificity ATG16L1 phosphorylation is oppositely regulated by CSNK2/casein kinase 2 and PPP1/protein phosphatase 1 which determines the fate of cardiomyocytes during hypoxia/reoxygenation.Folding of Intrinsically Disordered Protein Phosphatase 1 Regulatory Proteins.Cardiac-specific deletion of protein phosphatase 1β promotes increased myofilament protein phosphorylation and contractile alterations Human G109E-inhibitor-1 impairs cardiac function and promotes arrhythmias.Regulation of protein phosphatase 1 by intrinsically disordered proteins Protein Phosphatase 1c Associated with the Cardiac Sodium Calcium Exchanger 1 Regulates Its Activity by Dephosphorylating Serine 68-phosphorylated Phospholemman.Angiotensin IV upregulates the activity of protein phosphatase 1α in Neura-2A cells Molecular Insights into the Fungus-Specific Serine/Threonine Protein Phosphatase Z1 in Candida albicans

P2860

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P248

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P2860

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

http://www.wikidata.org/entity/Q24304144

description

2010 nî lūn-bûn

@nan

2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

@ast

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

@en

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

@en-gb

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

@nl

type

label

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

@ast

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

@en

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

@en-gb

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

@nl

prefLabel

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

@ast

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

@en

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

@en-gb

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

@nl

P1433

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P1476

Q24304144-F858CCF8-0666-45DF-930E-FA1F0E8D2073

P2093

Q24304144-265F6FAC-D0EB-4218-AAC3-99301D883EC6

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Q24304144-9C9EF6BE-7DD9-4F78-A56D-D9C255A79F91

Q24304144-F1D64FCF-8DA6-4860-AF7B-307F25EBE61D

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P2860

Q24304144-0DEE647C-2CC9-459D-8E04-F153E54A603B

Q24304144-27199DB9-AF2D-4FCE-AFF9-2C108063E701

Q24304144-2AFD1C8D-9327-43F6-B937-A2D845BE969F

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Q24304144-56EC2D7C-D4A9-46CD-8D7B-42E06721D971

P2888

Q24304144-7E520BA3-AC7E-4497-8995-1E2887AC8AE5

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P31

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P3181

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P433

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P478

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P50

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P577

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P5875

Q24304144-AB9693ED-0467-4110-BA0B-57EB1F3CE494

P6179

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P921

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P932

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P3181

P356

P1433

Nature Structural & Molecular Biology

P1476

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

@en

P2093

Barbara Dancheck

http://www.w3.org/2001/XMLSchema#string

David A Critton

http://www.w3.org/2001/XMLSchema#string

Michael J Ragusa

http://www.w3.org/2001/XMLSchema#string

Rebecca Page

http://www.w3.org/2001/XMLSchema#string

Wolfgang Peti

http://www.w3.org/2001/XMLSchema#string

P2860

Intrinsically unstructured proteins and their functions

Docking motif-guided mapping of the interactome of protein phosphatase-1

Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1

Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines

MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

Crystal structure of the tumor-promoter okadaic acid bound to protein phosphatase-1

Crystal structure of the complex between calyculin A and the catalytic subunit of protein phosphatase 1

Structural basis for regulation of protein phosphatase 1 by inhibitor-2

Crystal Structures of Protein Phosphatase-1 Bound to Nodularin-R and Tautomycin: A Novel Scaffold for Structure-based Drug Design of Serine/Threonine Phosphatase Inhibitors

Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1

P2888

P304

459-64

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

3826221

http://www.w3.org/2001/XMLSchema#string

P356

10.1038/NSMB.1786

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

17

http://www.w3.org/2001/XMLSchema#string

P50

P577

2010-04-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

42372612

http://www.w3.org/2001/XMLSchema#string

P6179

1035046377

http://www.w3.org/2001/XMLSchema#string

P698

20305656

http://www.w3.org/2001/XMLSchema#string

P921

structural biology

P932

2924587

http://www.w3.org/2001/XMLSchema#string