Contiguous stereogenic quaternary carbons: a daunting challenge in natural products synthesis
about
Highly functionalized donor-acceptor cyclopropanes applied toward the synthesis of the Melodinus alkaloidsWelwistatin support studies: expansion and limitation of aryllead(IV) coupling reactions.Diastereoselection in the formation of contiguous quaternary carbon stereocenters by the intramolecular Heck reaction.Diastereoselection in the formation of spirocyclic oxindoles by the intramolecular Heck reaction.Axial preferences in allylation reactions via the Zimmerman-Traxler transition state.Studies on the Himbert intramolecular arene/allene Diels-Alder cycloaddition. Mechanistic studies and expansion of scope to all-carbon tethers.Organometallic enantiomeric scaffolding. Sequential semipinacol/1,5-"Michael-like" reactions as a strategic approach to bridgehead-quaternary center aza[3.3.1]bicyclics: application to the total synthesis of (-)-adalinePalladium-catalysed formation of vicinal all-carbon quaternary centres via propargylationAsymmetric palladium-catalyzed intramolecular alpha-arylation of aldehydesPalladium-catalyzed asymmetric dearomatization of naphthalene derivatives.Synthesis of the tetracyclic core of exiguaquinol.Construction of spirolactones with concomitant formation of the fused quaternary centre--application to the synthesis of natural products.Construction of contiguous tetrasubstituted chiral carbon stereocenters via direct catalytic asymmetric aldol and Mannich-type reactions.The chemistry of the polycyclic polyprenylated acylphloroglucinols.Direct construction of vicinal all-carbon quaternary stereocenters in natural product synthesis.Recent Advances on the Total Syntheses of Communesin Alkaloids and Perophoramidine.Concise Total Synthesis of Dehaloperophoramidine.Total Synthesis of Dimeric HPI Alkaloids.Construction of Quaternary Stereogenic Centers in the Total Synthesis of Natural Products.Congested C-C bonds by Pd-catalyzed enantioselective allyl-allyl cross-coupling, a mechanism-guided solution.Determination of the absolute configuration of compounds bearing chiral quaternary carbon centers using the crystalline sponge method.Catalytic enantioselective claisen rearrangements of O-allyl β-ketoesters.Diastereospecific nazarov cyclization of fully substituted dienones: generation of vicinal all-carbon-atom quaternary stereocenters.Palladium-catalyzed asymmetric construction of vicinal all-carbon quaternary stereocenters and its application to the synthesis of cyclotryptamine alkaloids.Enantioselective construction of spirocyclic oxindolic cyclopentanes by palladium-catalyzed trimethylenemethane-[3+2]-cycloaddition.Studies on the Claisen rearrangements in the indolo[2,3-b]quinoline system.Asymmetric Michael addition reaction of 3-substituted-N-Boc oxindoles to activated terminal alkenes catalyzed by a bifunctional tertiary-amine thiourea catalyst.Iron-catalyzed oxidative C-H/C-H cross-coupling: an efficient route to α-quaternary α-amino acid derivatives.Asymmetric allylation of α-ketoester-derived N-benzoylhydrazones promoted by chiral sulfoxides/N-oxides Lewis bases: highly enantioselective synthesis of quaternary α-substituted α-allyl-α-amino acids.Enantioselective Construction of Acyclic Quaternary Carbon Stereocenters: Palladium-Catalyzed Decarboxylative Allylic Alkylation of Fully Substituted Amide Enolates.The synthesis and stereospecific solid-state photodecarbonylation of hexasubstituted meso- and d,l-ketones.Exposing the Molecular Screening Method of Indonesian Natural Products Derivate as Drug Candidates for Cervical Cancer.Diastereo- and enantioselective phase-transfer alkylation of 3-substituted oxindoles with racemic secondary alkyl halides.A catalytic enantioselective approach to tetrol bearing vicinal all-carbon quaternary stereogenic centers.Total Synthesis of Homodimericin A.Oxidative N-Heterocyclic Carbene Catalyzed Dearomatization of Indoles to Spirocyclic Indolenines with a Quaternary Carbon Stereocenter.Direct Access to N-Unprotected α- and/or β-Tetrasubstituted Amino Acid Esters via Direct Catalytic Mannich-Type Reactions Using N-Unprotected Trifluoromethyl Ketimines.Scandium-catalyzed asymmetric 1,6-addition of 3-substituted oxindoles to linear dienyl ketones.Enantioselective construction of vicinal tetrasubstituted stereocenters by the mannich reaction of silyl ketene imines with isatin-derived ketimines.Highly stereoselective conjugate addition and α-alkynylation reaction with electron-deficient alkynes catalyzed by chiral scandium(III) complexes.
P2860
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P2860
Contiguous stereogenic quaternary carbons: a daunting challenge in natural products synthesis
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Contiguous stereogenic quatern ...... in natural products synthesis
@ast
Contiguous stereogenic quatern ...... in natural products synthesis
@en
type
label
Contiguous stereogenic quatern ...... in natural products synthesis
@ast
Contiguous stereogenic quatern ...... in natural products synthesis
@en
prefLabel
Contiguous stereogenic quatern ...... in natural products synthesis
@ast
Contiguous stereogenic quatern ...... in natural products synthesis
@en
P2860
P356
P1476
Contiguous stereogenic quatern ...... in natural products synthesis
@en
P2093
Emily A Peterson
Larry E Overman
P2860
P304
11943-11948
P356
10.1073/PNAS.0402416101
P407
P577
2004-07-01T00:00:00Z