Effects of caffeine intake on the pharmacokinetics of melatonin, a probe drug for CYP1A2 activity. - Test2 - elhamkhani - TriplyDB

Effects of caffeine intake on the pharmacokinetics of melatonin, a probe drug for CYP1A2 activity.

Effects of caffeine intake on the pharmacokinetics of melatonin, a probe drug for CYP1A2 activity.

http://www.wikidata.org/entity/Q35825510

about

Melatonin: Characteristics, Concerns, and Prospects Urinary melatonin concentration and the risk of breast cancer in Nurses' Health Study II Winning a Won Game: Caffeine Panacea for Obesity Syndemic Urinary 6-Sulphatoxymelatonin levels and risk of breast cancer in premenopausal women: the ORDET cohort.Structure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2.Pharmacokinetics of oral and intravenous melatonin in healthy volunteers Melatonin Therapy in Patients with Alzheimer's Disease.Melatonin therapy to improve nocturnal sleep in critically ill patients: encouraging results from a small randomised controlled trial.Urinary 6-sulfatoxymelatonin levels and risk of breast cancer in postmenopausal women.Potential safety issues in the use of the hormone melatonin in paediatrics.Clinical pharmacokinetics of melatonin: a systematic review.The Safety of Melatonin in Humans.Pharmacokinetic Drug Interactions with Tobacco, Cannabinoids and Smoking Cessation Products.Quantitative Prediction of Drug Interactions Caused by CYP1A2 Inhibitors and Inducers.Inhibition of melatonin metabolism in humans induced by chemical components from herbs and effective prediction of this risk using a computational model.Pharmacokinetics of oral melatonin in patients recovering from critical illness.Effect of sodium valproate on nocturnal melatonin sensitivity to light in healthy volunteers.The effect of oral contraceptives on the pharmacokinetics of melatonin in healthy subjects with CYP1A2 g.-163C>A polymorphism.Melatonin pharmacokinetics in premenopausal and postmenopausal healthy female volunteers.Pharmacokinetics of Repeated Melatonin Drug Administrations Prior to and After Surgery.The neuroprotective role of melatonin in neurological disorders.Long-Term Melatonin Therapy for Adolescents and Young Adults with Chronic Sleep Onset Insomnia and Late Melatonin Onset: Evaluation of Sleep Quality, Chronotype, and Lifestyle Factors Compared to Age-Related Randomly Selected Population Cohorts.Effect of Caffeine Intake 12 or 24 Hours Prior to Melatonin Intake and CYP1A2*1F Polymorphism on CYP1A2 Phenotyping by Melatonin

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P2860

Effects of caffeine intake on the pharmacokinetics of melatonin, a probe drug for CYP1A2 activity.

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J.1365-2125.2003.01933.X

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British Journal of Clinical Pharmacology

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Anna Nordmark

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P2860

Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines

Brassica vegetables increase and apiaceous vegetables decrease cytochrome P450 1A2 activity in humans: changes in caffeine metabolite ratios in response to controlled vegetable diets

Phenotyping of drug-metabolizing enzymes in adults: a review of in-vivo cytochrome P450 phenotyping probes.

Habitual caffeine consumption and its relation to memory, attention, planning capacity and psychomotor performance across multiple age groups.

The effect of the CYP1A2 *1F mutation on CYP1A2 inducibility in pregnant women.

Inhibitory potency of quinolone antibacterial agents against cytochrome P450IA2 activity in vivo and in vitro.

Functional significance of a C-->A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine.

Use of caffeine metabolite ratios to explore CYP1A2 and xanthine oxidase activities.

Cytochrome P450 isoforms involved in melatonin metabolism in human liver microsomes.

Orally given melatonin may serve as a probe drug for cytochrome P450 1A2 activity in vivo: a pilot study.

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10.1046/J.1365-2125.2003.01933.X

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Leif Bertilsson

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2003-12-01T00:00:00Z

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