Identification of small-molecule antagonists that inhibit an activator: coactivator interaction. - Test2 - elhamkhani - TriplyDB

Identification of small-molecule antagonists that inhibit an activator: coactivator interaction.

Identification of small-molecule antagonists that inhibit an activator: coactivator interaction.

http://www.wikidata.org/entity/Q31134749

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Protein lysine acetylation by p300/CBP Enzyme Inhibition by Allosteric Capture of an Inactive Conformation Regulating the ARNT/TACC3 Axis: Multiple Approaches to Manipulating Protein/Protein Interactions with Small Molecules Control of CREB expression in tumors: from molecular mechanisms and signal transduction pathways to therapeutic target A Novel Small-Molecule Inhibitor Targeting CREB-CBP Complex Possesses Anti-Cancer Effects along with Cell Cycle Regulation, Autophagy Suppression and Endoplasmic Reticulum Stress Out of the shadows: CXC chemokines in promoting aberrant lung cancer angiogenesis The role of HTS in drug discovery at the University of Michigan.Trapping moving targets with small molecules.3',5'-cyclic adenosine monophosphate response element binding protein up-regulated cytochrome P450 lanosterol 14alpha-demethylase expression involved in follicle-stimulating hormone-induced mouse oocyte maturation.Identification of a small molecule inhibitor of serine 276 phosphorylation of the p65 subunit of NF-kappaB using in silico molecular docking.Transcriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition.Neurotrophic effect of citrus 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone: promotion of neurite outgrowth via cAMP/PKA/CREB pathway in PC12 cells CREB and the CRTC co-activators: sensors for hormonal and metabolic signals Novel Type of Prodrug Activation through a Long-Range O,N-Acyl Transfer: A Case of Water-Soluble CREB Inhibitor.Cyclic AMP inhibits p38 activation via CREB-induced dynein light chain.Molecular recognition by the KIX domain and its role in gene regulation.Targeting CREB for cancer therapy: friend or foe Distinct protein kinase A anchoring proteins direct prostaglandin E2 modulation of Toll-like receptor signaling in alveolar macrophages.Distinct signalling pathways of murine histamine H1- and H4-receptors expressed at comparable levels in HEK293 cells.Age-related decline in osteoblastogenesis and 1α-hydroxylase/CYP27B1 in human mesenchymal stem cells: stimulation by parathyroid hormone.Pharmacological manipulation of transcription factor protein-protein interactions: opportunities and obstacles CREB and leukemogenesis.A complex task? Direct modulation of transcription factors with small molecules.Identification of a Potent Inhibitor of CREB-Mediated Gene Transcription with Efficacious in Vivo Anticancer Activity.Angiotensin II regulates brain (pro)renin receptor expression through activation of cAMP response element-binding protein.Small molecule screen for inhibitors of expression from canonical CREB response element-containing promoters The novel therapeutic effect of phosphoinositide 3-kinase-γ inhibitor AS605240 in autoimmune diabetes.CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses Predicting the effect of transcription therapy in hematologic malignancies.E2F8 as a Novel Therapeutic Target for Lung Cancer Treponema pallidum (syphilis) antigen TpF1 induces angiogenesis through the activation of the IL-8 pathway Nuclear TRAF3 is a negative regulator of CREB in B cells.Cannabinoid agonists increase the interaction between β-Arrestin 2 and ERK1/2 and upregulate β-Arrestin 2 and 5-HT(2A) receptors.Structure-activity relationship studies of naphthol AS-E and its derivatives as anticancer agents by inhibiting CREB-mediated gene transcription RGS13 acts as a nuclear repressor of CREB.Sekikaic acid and lobaric acid target a dynamic interface of the coactivator CBP/p300.Cannabinoid-induced enhanced interaction and protein levels of serotonin 5-HT(2A) and dopamine D₂ receptors in rat prefrontal cortex.Identification, synthesis and evaluation of substituted benzofurazans as inhibitors of CREB-mediated gene transcription.Identification of genes, including the gene encoding p27Kip1, regulated by serine 276 phosphorylation of the p65 subunit of NF-kappaB Systemic Inhibition of CREB is Well-tolerated in vivo.

P2860

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P2860

Identification of small-molecule antagonists that inhibit an activator: coactivator interaction.

http://www.wikidata.org/entity/Q31134749

description

2004 nî lūn-bûn

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2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2004年の論文

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2004年学术文章

@wuu

2004年学术文章

@zh-cn

2004年学术文章

@zh-hans

2004年学术文章

@zh-my

2004年学术文章

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2004年學術文章

@yue

name

Identification of small-molecu ...... ator: coactivator interaction.

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Identification of small-molecu ...... ator: coactivator interaction.

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type

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Identification of small-molecu ...... ator: coactivator interaction.

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Identification of small-molecu ...... ator: coactivator interaction.

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Identification of small-molecu ...... ator: coactivator interaction.

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Identification of small-molecu ...... ator: coactivator interaction.

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Proceedings of the National Academy of Sciences of the United States of America

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Identification of small-molecu ...... ator: coactivator interaction.

@en

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Beverly Emerson

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Carlos A Amezcua

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Christopher M Murawsky

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Jennifer L Best

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Lawrence Flechner

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Marc Montminy

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P2860

Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells

TORCs: transducers of regulated CREB activity

Phosphorylation of CREB at Ser-133 induces complex formation with CREB-binding protein via a direct mechanism

MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein

Structure and interactions of PAS kinase N-terminal PAS domain: model for intramolecular kinase regulation

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

Solution Structure of the KIX Domain of CBP Bound to the Transactivation Domain of CREB: A Model for Activator:Coactivator Interactions

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

NMR View: A computer program for the visualization and analysis of NMR data

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

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17622-17627

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scholarly article

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10.1073/PNAS.0406374101

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51

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101

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Kevin H. Gardner

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2004-12-07T00:00:00Z

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8141618

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15585582

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539725

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