A quantitative high-throughput in vitro splicing assay identifies inhibitors of spliceosome catalysis.
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Modulating splicing with small molecular inhibitors of the spliceosomeIdentification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation.A high-throughput splicing assay identifies new classes of inhibitors of human and yeast spliceosomesMotor neuron disease. SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy.Identification of small molecule inhibitors of pre-mRNA splicing.Small Molecule, NSC95397, Inhibits the CtBP1-Protein Partner Interaction and CtBP1-Mediated Transcriptional Repression.The Natural Product N-Palmitoyl-l-leucine Selectively Inhibits Late Assembly of Human SpliceosomesATPγS stalls splicing after B complex formation but prior to spliceosome activation.Small Molecule Modulators of Pre-mRNA Splicing in Cancer TherapyHuman spliceosomal protein CWC22 plays a role in coupling splicing to exon junction complex deposition and nonsense-mediated decay.Genomics-guided discovery of thailanstatins A, B, and C As pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43Multiple components of the spliceosome regulate Mcl1 activity in neuroblastoma.The Role of CtBP1 in Oncogenic Processes and Its Potential as a Therapeutic Target.Therapeutic targeting of splicing in cancer.Copy-number and gene dependency analysis reveals partial copy loss of wild-type SF3B1 as a novel cancer vulnerability.Telomere dysfunction drives aberrant hematopoietic differentiation and myelodysplastic syndrome.Molecular architecture of zinc chelating small molecules that inhibit spliceosome assembly at an early stage.Structure of a human catalytic step I spliceosome.
P2860
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P2860
A quantitative high-throughput in vitro splicing assay identifies inhibitors of spliceosome catalysis.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
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2012年论文
@zh-cn
name
A quantitative high-throughput ...... tors of spliceosome catalysis.
@ast
A quantitative high-throughput ...... tors of spliceosome catalysis.
@en
type
label
A quantitative high-throughput ...... tors of spliceosome catalysis.
@ast
A quantitative high-throughput ...... tors of spliceosome catalysis.
@en
prefLabel
A quantitative high-throughput ...... tors of spliceosome catalysis.
@ast
A quantitative high-throughput ...... tors of spliceosome catalysis.
@en
P2093
P2860
P356
P1476
A quantitative high-throughput ...... tors of spliceosome catalysis.
@en
P2093
Congli Wang
Gideon Dreyfuss
Ihab Younis
Michael D Diem
Michael G Berg
Michael Soo
P2860
P304
P356
10.1128/MCB.05788-11
P407
P577
2012-01-17T00:00:00Z