Multivalent binding and facilitated diffusion account for the formation of the Grb2-Sos1 signaling complex in a cooperative manner.
about
Regions outside of conserved PxxPxR motifs drive the high affinity interaction of GRB2 with SH3 domain ligandsAllostery mediates ligand binding to Grb2 adaptor in a mutually exclusive manner.Structural landscape of the proline-rich domain of Sos1 nucleotide exchange factorRule-based modeling: a computational approach for studying biomolecular site dynamics in cell signaling systems.Integrative biology of T cell activation.
P2860
Multivalent binding and facilitated diffusion account for the formation of the Grb2-Sos1 signaling complex in a cooperative manner.
description
2012 nî lūn-bûn
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2012年の論文
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name
Multivalent binding and facili ...... mplex in a cooperative manner.
@ast
Multivalent binding and facili ...... mplex in a cooperative manner.
@en
type
label
Multivalent binding and facili ...... mplex in a cooperative manner.
@ast
Multivalent binding and facili ...... mplex in a cooperative manner.
@en
prefLabel
Multivalent binding and facili ...... mplex in a cooperative manner.
@ast
Multivalent binding and facili ...... mplex in a cooperative manner.
@en
P2093
P2860
P356
P1433
P1476
Multivalent binding and facili ...... mplex in a cooperative manner.
@en
P2093
Amjad Farooq
Brian J Deegan
Caleb B McDonald
David C Mikles
Jordan E Balke
Kenneth L Seldeen
Vikas Bhat
P2860
P304
P356
10.1021/BI3000534
P407
P577
2012-03-02T00:00:00Z