Enhanced virus resistance of transgenic mice expressing the human MxA protein.
about
MxA overexpression reveals a common genetic link in four Fanconi anemia complementation groupsMxA GTPase blocks reporter gene expression of reconstituted Thogoto virus ribonucleoprotein complexesAntiviral actions of interferonsDominant-negative mutants of human MxA protein: domains in the carboxy-terminal moiety are important for oligomerization and antiviral activitySensitivity of human pleural mesothelioma to oncolytic measles virus depends on defects of the type I interferon response.Human MxA protein protects mice lacking a functional alpha/beta interferon system against La crosse virus and other lethal viral infectionsTransgenic cell lines for detection of animal virusesInhibition of bunyaviruses, phleboviruses, and hantaviruses by human MxA proteinDisease-promoting effects of type I interferons in viral, bacterial, and coinfectionsInterferon-induced human MxA GTPase blocks nuclear import of Thogoto virus nucleocapsids.Intranasal administration of alpha interferon reduces seasonal influenza A virus morbidity in ferretsIn vivo evasion of MxA by avian influenza viruses requires human signature in the viral nucleoprotein.The role of interferon antagonist, non-structural proteins in the pathogenesis and emergence of arboviruses.Pathogenic potential of interferon αβ in acute influenza infectionThe cytoplasmic location of chicken mx is not the determining factor for its lack of antiviral activityInhibition of hepatitis B virus replication by the interferon-inducible MxA protein.Innate immunity to influenza virus infection.Regulation of human immunodeficiency virus replication by 2',5'-oligoadenylate-dependent RNase L.Production of transgenic pigs over-expressing the antiviral gene Mx1.Antagonistic antiviral activity between IFN-lambda and IFN-alpha against lethal Crimean-Congo hemorrhagic fever virus in vitro.Role of nucleotide binding and GTPase domain dimerization in dynamin-like myxovirus resistance protein A for GTPase activation and antiviral activity.Antiviral effects of geranylgeranylacetone: enhancement of MxA expression and phosphorylation of PKR during influenza virus infection.Oligoadenylate synthetase/protein kinase R pathways and alphabeta TCR+ T cells are required for adenovirus vector: IFN-gamma inhibition of herpes simplex virus-1 in cornea.Pathogenesis of Ebola hemorrhagic fever in cynomolgus macaques: evidence that dendritic cells are early and sustained targets of infectionA double-stranded-RNA response program important for RNA interference efficiencyMaturation, activation, and protection of dendritic cells induced by double-stranded RNAIdentification of avian RIG-I responsive genes during influenza infectionThe myxovirus resistance A (MxA) gene -88G>T single nucleotide polymorphism is associated with prostate cancer.A genetic model of differential susceptibility to human respiratory syncytial virus (RSV) infection.Mx proteins: antiviral gatekeepers that restrain the uninvited.Interferon-Inducible GTPases in Host Resistance, Inflammation and Disease.Hantavirus infection of dendritic cells.The clinically approved proteasome inhibitor PS-341 efficiently blocks influenza A virus and vesicular stomatitis virus propagation by establishing an antiviral state.Thogoto virus lacking interferon-antagonistic protein ML is strongly attenuated in newborn Mx1-positive but not Mx1-negative mice.Variable deficiencies in the interferon response enhance susceptibility to vesicular stomatitis virus oncolytic actions in glioblastoma cells but not in normal human glial cells.IFNλ is a potent anti-influenza therapeutic without the inflammatory side effects of IFNα treatment.Nuclear MxA proteins form a complex with influenza virus NP and inhibit the transcription of the engineered influenza virus genome.Comparative genetics of resistance to viruses
P2860
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P2860
Enhanced virus resistance of transgenic mice expressing the human MxA protein.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Enhanced virus resistance of transgenic mice expressing the human MxA protein.
@ast
Enhanced virus resistance of transgenic mice expressing the human MxA protein.
@en
type
label
Enhanced virus resistance of transgenic mice expressing the human MxA protein.
@ast
Enhanced virus resistance of transgenic mice expressing the human MxA protein.
@en
prefLabel
Enhanced virus resistance of transgenic mice expressing the human MxA protein.
@ast
Enhanced virus resistance of transgenic mice expressing the human MxA protein.
@en
P2093
P2860
P1433
P1476
Enhanced virus resistance of transgenic mice expressing the human MxA protein
@en
P2093
Pavlovic J
Staeheli P
P2860
P304
P407
P577
1995-07-01T00:00:00Z