Cooperative assembly of higher-order Notch complexes functions as a switch to induce transcription.
about
From dynamic expression patterns to boundary formation in the presomitic mesodermInteraction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathwaysFast synchronization of ultradian oscillators controlled by delta-notch signaling with cis-inhibition.Ligand-independent traffic of Notch buffers activated Armadillo in DrosophilaStructure and Function of the Su(H)-Hairless Repressor Complex, the Major Antagonist of Notch Signaling in Drosophila melanogasterRAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription ComplexThermodynamic and structural insights into CSL-DNA complexesStructural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexesConformational Locking upon Cooperative Assembly of Notch Transcription ComplexesNotch3 is dispensable for thymocyte β-selection and Notch1-induced T cell leukemogenesisThe canonical Notch signaling pathway: unfolding the activation mechanism.A NOTCH-sensitive uPAR-regulated oncolytic adenovirus effectively suppresses pancreatic tumor growth and triggers synergistic anticancer effects with gemcitabine and nab-paclitaxelAlpha-secretase inhibition reduces human glioblastoma stem cell growth in vitro and in vivo by inhibiting Notch.Notch inhibitors as a new tool in the war on cancer: a pathway to watch.Sequence conservation and combinatorial complexity of Drosophila neural precursor cell enhancers.Notch ankyrin repeat domain variation influences leukemogenesis and Myc transactivation.The Enhancer of split complex arose prior to the diversification of schizophoran flies and is strongly conserved between Drosophila and stalk-eyed flies (Diopsidae)Expression of the oscillating gene her1 is directly regulated by Hairy/Enhancer of Split, T-box, and Suppressor of Hairless proteins in the zebrafish segmentation clock.Notch dimerization is required for leukemogenesis and T-cell development.Notch inhibitors for cancer treatment.Notch signalling in T-cell lymphoblastic leukaemia/lymphoma and other haematological malignancies.Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemiaTranscriptional dynamics elicited by a short pulse of notch activation involves feed-forward regulation by E(spl)/Hes genes.Transcriptional repression in the Notch pathway: thermodynamic characterization of CSL-MINT (Msx2-interacting nuclear target protein) complexesAssembly of a Notch transcriptional activation complex requires multimerization.Transcription factor RBPJ/CSL: a genome-wide look at transcriptional regulationAnalyzing the nuclear complexes of Notch signaling by electrophoretic mobility shift assayThe EBNA-2 N-Terminal Transactivation Domain Folds into a Dimeric Structure Required for Target Gene Activation.The drosophila T-box transcription factor midline functions within Insulin/Akt and c-Jun-N terminal kinase stress-reactive signaling pathways to regulate interommatial bristle formation and cell survival.Insights into Autoregulation of Notch3 from Structural and Functional Studies of Its Negative Regulatory Regionp53 Modulates Notch Signaling in MCF-7 Breast Cancer Cells by Associating With the Notch Transcriptional Complex Via MAML1SpDamID: Marking DNA Bound by Protein Complexes Identifies Notch-Dimer Responsive Enhancers.Characterization of CSL (CBF-1, Su(H), Lag-1) mutants reveals differences in signaling mediated by Notch1 and Notch2.Ikaros represses the transcriptional response to Notch signaling in T-cell development.Notch signaling in leukemia.Notch signaling mediates G1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinasesProteomics-based identification of novel factor inhibiting hypoxia-inducible factor (FIH) substrates indicates widespread asparaginyl hydroxylation of ankyrin repeat domain-containing proteins.Notch-1 activates estrogen receptor-alpha-dependent transcription via IKKalpha in breast cancer cells.Competition and collaboration: GATA-3, PU.1, and Notch signaling in early T-cell fate determination.Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A.
P2860
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P2860
Cooperative assembly of higher-order Notch complexes functions as a switch to induce transcription.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Cooperative assembly of higher ...... witch to induce transcription.
@ast
Cooperative assembly of higher ...... witch to induce transcription.
@en
type
label
Cooperative assembly of higher ...... witch to induce transcription.
@ast
Cooperative assembly of higher ...... witch to induce transcription.
@en
prefLabel
Cooperative assembly of higher ...... witch to induce transcription.
@ast
Cooperative assembly of higher ...... witch to induce transcription.
@en
P2093
P2860
P356
P1476
Cooperative assembly of higher ...... witch to induce transcription.
@en
P2093
Jon C Aster
Stephen C Blacklow
Warren S Pear
Yunsun Nam
P2860
P304
P356
10.1073/PNAS.0611092104
P407
P50
P577
2007-02-06T00:00:00Z