Human immunodeficiency virus Type 1 nucleocapsid protein (NCp7) directs specific initiation of minus-strand DNA synthesis primed by human tRNA(Lys3) in vitro: studies of viral RNA molecules mutated in regions that flank the primer binding site
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Inhibition of HIV-1 replication by a bis-thiadiazolbenzene-1,2-diamine that chelates zinc ions from retroviral nucleocapsid zinc fingersA single zinc finger optimizes the DNA interactions of the nucleocapsid protein of the yeast retrotransposon Ty3.Inhibitors of human immunodeficiency virus type 1 reverse transcriptase target distinct phases of early reverse transcriptionPrimer tRNAs for reverse transcriptionHuman immunodeficiency virus type 1 nucleocapsid protein can prevent self-priming of minus-strand strong stop DNA by promoting the annealing of short oligonucleotides to hairpin sequences.Zinc finger structures in the human immunodeficiency virus type 1 nucleocapsid protein facilitate efficient minus- and plus-strand transferInteraction of the human immunodeficiency virus type 1 nucleocapsid with actin.Human immunodeficiency virus type 1 integrase protein promotes reverse transcription through specific interactions with the nucleoprotein reverse transcription complex.Functional domains of Tat required for efficient human immunodeficiency virus type 1 reverse transcription.The nucleocapsid protein specifically anneals tRNALys-3 onto a noncomplementary primer binding site within the HIV-1 RNA genome in vitro.Actinomycin D inhibits human immunodeficiency virus type 1 minus-strand transfer in in vitro and endogenous reverse transcriptase assays.Molecular requirements for human immunodeficiency virus type 1 plus-strand transfer: analysis in reconstituted and endogenous reverse transcription systems.Translation elongation factor 1-alpha interacts specifically with the human immunodeficiency virus type 1 Gag polyproteinChanges in Rous sarcoma virus RNA secondary structure near the primer binding site upon tRNATrp primer annealing.In vitro analysis of human immunodeficiency virus type 1 minus-strand strong-stop DNA synthesis and genomic RNA processing.Human immunodeficiency virus type 1 central DNA flap: dynamic terminal product of plus-strand displacement dna synthesis catalyzed by reverse transcriptase assisted by nucleocapsid protein.Moloney murine leukemia virus integrase protein augments viral DNA synthesis in infected cells.Role for human immunodeficiency virus type 1 Tat protein in suppression of viral reverse transcriptase activity during late stages of viral replication.The yeast Ty3 retrotransposon contains a 5'-3' bipartite primer-binding site and encodes nucleocapsid protein NCp9 functionally homologous to HIV-1 NCp7A succession of mechanisms stimulate efficient reconstituted HIV-1 minus strand strong stop DNA transferBiophysical characterization of DNA binding from single molecule force measurementsZinc finger domain of murine leukemia virus nucleocapsid protein enhances the rate of viral DNA synthesis in vivo.A Leu to Ile but not Leu to Val change at HIV-1 reverse transcriptase codon 74 in the background of K65R mutation leads to an increased processivity of K65R+L74I enzyme and a replication competent virus.The primer binding site on the RNA genome of human and simian immunodeficiency viruses is flanked by an upstream hairpin structure.Mapping the RNA binding sites for human immunodeficiency virus type-1 gag and NC proteins within the complete HIV-1 and -2 untranslated leader regions.Role of HIV-1 nucleocapsid protein in HIV-1 reverse transcription.Subtle alterations of the native zinc finger structures have dramatic effects on the nucleic acid chaperone activity of human immunodeficiency virus type 1 nucleocapsid proteinHuman immunodeficiency virus type 2 reverse transcriptase activity in model systems that mimic steps in reverse transcription.Nucleocapsid protein annealing of a primer-template enhances (+)-strand DNA synthesis and fidelity by HIV-1 reverse transcriptase.Human immunodeficiency virus type 1 nucleocapsid protein promotes efficient strand transfer and specific viral DNA synthesis by inhibiting TAR-dependent self-priming from minus-strand strong-stop DNA.The importance of the A-rich loop in human immunodeficiency virus type 1 reverse transcription and infectivity.Identification of sequences downstream of the primer binding site that are important for efficient replication of human immunodeficiency virus type 1.Mechanism for nucleic acid chaperone activity of HIV-1 nucleocapsid protein revealed by single molecule stretching.Molecular mechanisms by which human immunodeficiency virus type 1 integrase stimulates the early steps of reverse transcription.A mimic of HIV-1 nucleocapsid protein impairs reverse transcription and displays antiviral activity.The roles of the human immunodeficiency virus type 1 Pol protein and the primer binding site in the placement of primer tRNA(3Lys) onto viral genomic RNA.Retroviral nucleocapsid proteins display nonequivalent levels of nucleic acid chaperone activity.Human immunodeficiency virus type 1 nucleocapsid inhibitors impede trans infection in cellular and explant models and protect nonhuman primates from infection.Comparative analysis of in vitro processivity of HIV-1 reverse transcriptases containing mutations 65R, 74V, 184V and 65R+74V.The HIV-1 nucleocapsid protein recruits negatively charged lipids to ensure its optimal binding to lipid membranes
P2860
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P2860
Human immunodeficiency virus Type 1 nucleocapsid protein (NCp7) directs specific initiation of minus-strand DNA synthesis primed by human tRNA(Lys3) in vitro: studies of viral RNA molecules mutated in regions that flank the primer binding site
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Human immunodeficiency virus T ...... flank the primer binding site
@ast
Human immunodeficiency virus T ...... flank the primer binding site
@en
type
label
Human immunodeficiency virus T ...... flank the primer binding site
@ast
Human immunodeficiency virus T ...... flank the primer binding site
@en
prefLabel
Human immunodeficiency virus T ...... flank the primer binding site
@ast
Human immunodeficiency virus T ...... flank the primer binding site
@en
P2093
P2860
P1433
P1476
Human immunodeficiency virus T ...... flank the primer binding site
@en
P2093
Parniak MA
Preston BD
Wainberg MA
P2860
P304
P407
P577
1996-08-01T00:00:00Z