A single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with the ability to cause growth hormone deficiency syndrome
about
Pathogenicity of Hantaan virus in newborn mice: genetic reassortant study demonstrating that a single amino acid change in glycoprotein G1 is related to virulenceInhibition of cellular entry of lymphocytic choriomeningitis virus by amphipathic DNA polymersRetroviral vectors pseudotyped with lymphocytic choriomeningitis virus.Differences in affinity of binding of lymphocytic choriomeningitis virus strains to the cellular receptor alpha-dystroglycan correlate with viral tropism and disease kinetics.Old world arenaviruses enter the host cell via the multivesicular body and depend on the endosomal sorting complex required for transportPosttranslational modification of alpha-dystroglycan, the cellular receptor for arenaviruses, by the glycosyltransferase LARGE is critical for virus binding.Mutagenesis-mediated decrease of pathogenicity as a feature of the mutant spectrum of a viral population.New World arenavirus clade C, but not clade A and B viruses, utilizes alpha-dystroglycan as its major receptorOptimized lentiviral transduction of mouse bone marrow-derived mesenchymal stem cellsArenavirus variations due to host-specific adaptation.Old World and clade C New World arenaviruses mimic the molecular mechanism of receptor recognition used by alpha-dystroglycan's host-derived ligands.Variants able to cause growth hormone deficiency syndrome are present within the disease-nil WE strain of lymphocytic choriomeningitis virusEvaluation of pneumonia virus of mice as a possible human pathogenImmunosuppression and resultant viral persistence by specific viral targeting of dendritic cellsCrystal structure of the prefusion surface glycoprotein of the prototypic arenavirus LCMVLymphocytic choriomeningitis infection of the central nervous system.Arenaviruses and lethal mutagenesis. Prospects for new ribavirin-based interventions.Mutational Analysis of Lassa Virus Glycoprotein Highlights Regions Required for Alpha-Dystroglycan Utilization.Characterization of Lassa virus cell entry and neutralization with Lassa virus pseudoparticlesStructural basis for antibody-mediated neutralization of Lassa virus.Characterization of the interaction of lassa fever virus with its cellular receptor alpha-dystroglycan
P2860
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P2860
A single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with the ability to cause growth hormone deficiency syndrome
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
A single amino acid change in ...... th hormone deficiency syndrome
@ast
A single amino acid change in ...... th hormone deficiency syndrome
@en
type
label
A single amino acid change in ...... th hormone deficiency syndrome
@ast
A single amino acid change in ...... th hormone deficiency syndrome
@en
prefLabel
A single amino acid change in ...... th hormone deficiency syndrome
@ast
A single amino acid change in ...... th hormone deficiency syndrome
@en
P2093
P2860
P1433
P1476
A single amino acid change in ...... th hormone deficiency syndrome
@en
P2093
J C de la Torre
M B Oldstone
P2860
P304
P407
P577
1996-12-01T00:00:00Z