Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells. - Test2 - elhamkhani - TriplyDB

Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells.

Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells.

http://www.wikidata.org/entity/Q35887221

about

Therapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targeting Histone lysine-specific methyltransferases and demethylases in carcinogenesis: new targets for cancer therapy and prevention Epigenetics of Alzheimer's disease and frontotemporal dementia Quantitative-proteomic comparison of alpha and Beta cells to uncover novel targets for lineage reprogramming Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity Molecular biology of liver cancer stem cells.Alpha-interferon suppresses hepadnavirus transcription by altering epigenetic modification of cccDNA minichromosomes CellFateScout - a bioinformatics tool for elucidating small molecule signaling pathways that drive cells in a specific direction Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types Medulloblastoma biology in the post-genomic era.Artificial zinc finger DNA binding domains: versatile tools for genome engineering and modulation of gene expression.Characteristics of hepatic stem/progenitor cells in the fetal and adult liver.Developmental and environmental epigenetic programming of the endocrine pancreas: consequences for type 2 diabetes.Epigenetic regulation of pancreatic islets.Notch signaling in the pancreas: patterning and cell fate specification.Reversible LSD1 inhibition interferes with global EWS/ETS transcriptional activity and impedes Ewing sarcoma tumor growth.HDAC1 and HDAC2 integrate the expression of p53 mutants in pancreatic cancer.Plasticity and dedifferentiation within the pancreas: development, homeostasis, and disease.Boolean network modeling in systems pharmacology.Network perturbation analysis of gene transcriptional profiles reveals protein targets and mechanism of action of drugs and influenza A viral infection.Epigenetik in der Onkologie

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P2860

Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells.

http://www.wikidata.org/entity/Q35887221

description

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2012年论文

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2012年论文

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2012年论文

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name

Chromatin-targeting small mole ...... in pancreatic endocrine cells.

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Chromatin-targeting small mole ...... in pancreatic endocrine cells.

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type

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Chromatin-targeting small mole ...... in pancreatic endocrine cells.

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Chromatin-targeting small mole ...... in pancreatic endocrine cells.

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prefLabel

Chromatin-targeting small mole ...... in pancreatic endocrine cells.

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Chromatin-targeting small mole ...... in pancreatic endocrine cells.

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PNAS.1201079109

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Chromatin-targeting small mole ...... in pancreatic endocrine cells

@en

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Alexander D Gitlin

http://www.w3.org/2001/XMLSchema#string

Alykhan F Shamji

http://www.w3.org/2001/XMLSchema#string

Bradley Taylor

http://www.w3.org/2001/XMLSchema#string

Bridget K Wagner

http://www.w3.org/2001/XMLSchema#string

Dina Fomina-Yadlin

http://www.w3.org/2001/XMLSchema#string

Edward B Holson

http://www.w3.org/2001/XMLSchema#string

Florence F Wagner

http://www.w3.org/2001/XMLSchema#string

Joshua C Gilbert

http://www.w3.org/2001/XMLSchema#string

Paul A Clemons

http://www.w3.org/2001/XMLSchema#string

Stuart L Schreiber

http://www.w3.org/2001/XMLSchema#string

P2860

Translating the Histone Code

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses

Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells

Histone deacetylase inhibitors: Potential in cancer therapy

Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

Genomewide studies of histone deacetylase function in yeast

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10.1073/PNAS.1201079109

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109

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221878383

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