Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.
about
Synthetic lethality: emerging targets and opportunities in melanoma.Genome-scale CRISPR-Cas9 knockout and transcriptional activation screeningCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation.A High-Throughput Strategy for Dissecting Mammalian Genetic Interactions.Genome-wide mapping of mutations at single-nucleotide resolution for protein, metabolic and genome engineering.Functional interrogation of non-coding DNA through CRISPR genome editing.Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactionsInferring modulators of genetic interactions with epistatic nested effects models.Optimization of genome editing through CRISPR-Cas9 engineeringPredictability of Genetic Interactions from Functional Gene Modules.Progress and Application of CRISPR/Cas Technology in Biological and Biomedical Investigation.Applications of CRISPR genome editing technology in drug target identification and validation.Synthetic lethality and cancer.Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions.CRISPR-Cas9 technology: applications in genome engineering, development of sequence-specific antimicrobials, and future prospects.A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy.The applications of CRISPR screen in functional genomics.A comprehensive overview of computational resources to aid in precision genome editing with engineered nucleases.Applications of CRISPR Genome Engineering in Cell Biology.Potential of long non-coding RNAs in cancer patients: From biomarkers to therapeutic targets.Mammalian synthetic biology in the age of genome editing and personalized medicine.CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine.Randomized CRISPR-Cas Transcriptional Perturbation Screening Reveals Protective Genes against Alpha-Synuclein Toxicity.FnCpf1: a novel and efficient genome editing tool for Saccharomyces cerevisiae.Current status and perspectives of genome editing technology for microalgae.Am I ready for CRISPR? A user's guide to genetic screens.CRISPR/Cas9 library screening for drug target discovery.Target Discovery for Precision Medicine Using High-Throughput Genome Engineering.From Reductionism to Holism: Toward a More Complete View of Development Through Genome Engineering.High-Throughput Approaches to Pinpoint Function within the Noncoding Genome.Orthologous CRISPR-Cas9 enzymes for combinatorial genetic screens.Combinatorial CRISPR-Cas9 Metabolic Screens Reveal Critical Redox Control Points Dependent on the KEAP1-NRF2 Regulatory Axis.Application of CRISPR-Cas9 Based Genome-Wide Screening Approaches to Study Cellular Signalling Mechanisms.Choosing CRISPR-based screens in cancer.Single-cell CRISPR screening in drug resistance.Uncoupling of sgRNAs from their associated barcodes during PCR amplification of combinatorial CRISPR screens.
P2860
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P2860
Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.
@ast
Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.
@en
type
label
Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.
@ast
Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.
@en
prefLabel
Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.
@ast
Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.
@en
P2093
P2860
P50
P356
P1476
Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.
@en
P2093
Aleth Gaillard
Cheryl H Cui
Gigi C G Choi
Mario Hermann
Miriam Adam
Pamela Milani
Samuel D Perli
Samuel W Kazer
Timothy K Lu
P2860
P304
P356
10.1073/PNAS.1517883113
P407
P577
2016-02-10T00:00:00Z