Perlecan modulates VEGF signaling and is essential for vascularization in endochondral bone formation. - Test2 - elhamkhani - TriplyDB

Perlecan modulates VEGF signaling and is essential for vascularization in endochondral bone formation.

Perlecan modulates VEGF signaling and is essential for vascularization in endochondral bone formation.

http://www.wikidata.org/entity/Q35923316

about

Proteoglycan form and function: A comprehensive nomenclature of proteoglycans Endorepellin laminin-like globular 1/2 domains bind Ig3-5 of vascular endothelial growth factor (VEGF) receptor 2 and block pro-angiogenic signaling by VEGFA in endothelial cells The role of perlecan and endorepellin in the control of tumor angiogenesis and endothelial cell autophagy Regulation of valve endothelial cell vasculogenic network architectures with ROCK and Rac inhibitors.A current view of perlecan in physiology and pathology: A mosaic of functions.Endorepellin evokes autophagy in endothelial cells Coexpression and expression quantitative trait loci analyses of the angiogenesis gene-gene interaction network in prostate cancer.Perlecan maintains microvessel integrity in vivo and modulates their formation in vitro Fibulin-1 is required for bone formation and Bmp-2-mediated induction of Osterix.Cell-bricks based injectable niche guided persistent ectopic chondrogenesis of bone marrow-derived mesenchymal stem cells and enabled nasal augmentation Matrilysin/matrix metalloproteinase-7(MMP7) cleavage of perlecan/HSPG2 creates a molecular switch to alter prostate cancer cell behavior.The biology of the extracellular matrix: novel insights.Endostatin and endorepellin: A common route of action for similar angiostatic cancer avengers Pannexin 3 and connexin 43 modulate skeletal development through their distinct functions and expression patterns.The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling.A novel transgenic mouse model of growth plate dysplasia reveals that decreased chondrocyte proliferation due to chronic ER stress is a key factor in reduced bone growth.Synovial perlecan is required for osteophyte formation in knee osteoarthritis.Border patrol: insights into the unique role of perlecan/heparan sulfate proteoglycan 2 at cell and tissue borders Perlecan is required for FGF-2 signaling in the neural stem cell niche Role and regulation of vascularization processes in endochondral bones.Extracellular matrix and developing growth plate.Proteoglycans: Potential Agents in Mammographic Density and the Associated Breast Cancer Risk.Heparan sulfate proteoglycans as key regulators of the mesenchymal niche of hematopoietic stem cells.The Role of Pannexin 3 in Bone Biology.Perlecan deficiency causes endothelial dysfunction by reducing the expression of endothelial nitric oxide synthase.Multipotent adult progenitor cells on an allograft scaffold facilitate the bone repair process.The heparan sulphate deficient Hspg2 exon 3 null mouse displays reduced deposition of TGF-β1 in skin compared to C57BL/6 wild type mice.Perlecan is required for the chondrogenic differentiation of synovial mesenchymal cells through regulation of Sox9 gene expression.

P2860

Q21710680-1F79DA28-7F29-4E92-AE77-978B5F9F61C1 Q24312922-60F27C13-2357-474F-947E-24A8207DEE12 Q26800258-720C32F0-1804-4EBA-92E0-64D8F5468580 Q27308671-CE859D2C-82CC-4355-B680-FD3F7E1FCD8F Q30392738-D2D2A722-E2C7-43BD-8ACE-135EDFD5EF94 Q33718473-3C354169-AC05-4B7F-A685-F16F921A548D Q33838280-93B6DE00-9BBB-4DD7-8B61-7A22BCCCF019 Q34548326-1CF907EC-315D-4CBB-A6F5-FA85AE3A732A Q35267375-8FAA3869-D313-4697-9AE0-50F97058133F Q35413003-BD7068D3-F093-42E6-B4DF-B15C1F56D156 Q36566641-C732D12E-B037-40AA-836E-26C1E0A1E85A Q36576213-40E7248F-D7B3-4840-89BE-9951894C4CA3 Q36578668-82E698CE-CF7D-428F-BECB-F75B8CA545A5 Q36743963-088F7B98-AF97-4885-B3AC-0E03558F3CDD Q37271260-A62A611B-0B7F-41BF-AD45-7138FC6B642F Q37287446-97C1500C-A223-4268-8A66-16F8907B564A Q37349431-225F3EC9-2B51-4F81-A175-780182C37408 Q37610826-4B6E8045-AD99-42A1-8631-4FCB5FF29A35 Q37634536-0FC3C194-20DD-46AF-ADE0-3349C7FA0C8B Q38071918-707E4CFB-A3BC-437D-9B11-E101910B1ABD Q38248420-02616D90-A403-4A4C-A8C0-1CD707F814D3 Q38616484-8B365198-97AC-43F1-A3A7-C346253764B4 Q38747421-8A81AD75-2D0A-4C7E-8571-75AD135F4FA8 Q39005939-0FD29433-B4F6-41D8-A58B-DD33CF62E10D Q39321049-E41082F6-BC13-4918-8ADF-4F64F3E6A816 Q42406826-889E584B-9707-4A93-9857-569248E22BD2 Q51363492-6DA0F791-5AF3-4D52-BACC-217D55D9CC39 Q53604003-4F43280E-7F69-4020-A700-497030D8C346

P2860

Perlecan modulates VEGF signaling and is essential for vascularization in endochondral bone formation.

http://www.wikidata.org/entity/Q35923316

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

Perlecan modulates VEGF signal ...... n endochondral bone formation.

@ast

Perlecan modulates VEGF signal ...... n endochondral bone formation.

@en

type

label

Perlecan modulates VEGF signal ...... n endochondral bone formation.

@ast

Perlecan modulates VEGF signal ...... n endochondral bone formation.

@en

prefLabel

Perlecan modulates VEGF signal ...... n endochondral bone formation.

@ast

Perlecan modulates VEGF signal ...... n endochondral bone formation.

@en

P1433

Q35923316-681B4661-74E6-4C16-B922-8F59F2A03BE8

P1476

Q35923316-FAC7D77F-5DF3-4EE3-9A4A-A911ECD1454A

P2093

Q35923316-0ADECD56-C622-485D-84BF-D6346BDE8DE4

Q35923316-24830C1C-260D-4780-BC42-89CA730421EB

Q35923316-3A85B45E-7AEB-4795-A331-BE0F675B83AC

Q35923316-4FB355E6-749C-431E-872D-B79D6F7000D1

Q35923316-820EC716-C9DC-46C4-B4FB-8D078474BA8A

Q35923316-9A674F73-19D6-47DD-B133-D027A42D36B9

Q35923316-BD8E7A72-EE1F-4640-9543-D51C814E81B8

Q35923316-CCB0A703-CD09-4950-99AA-3827A35A05D0

Q35923316-F33B2967-2C11-4DB3-A318-D0FA74A624D7

P2860

Q35923316-06CC484D-0F05-4859-B77A-DB8541CAFE6D

Q35923316-0B307C67-6700-4045-866C-0F795431859F

Q35923316-0C28744B-98D8-417F-B477-70CC45B44AE6

Q35923316-0C57CD1C-EC8E-43FA-96AC-A366F1A28CCB

Q35923316-160DFA7C-261A-445D-8206-BAFAA34F4E9B

Q35923316-17279FC4-F4A0-4F87-BC48-211A3B45D2D5

Q35923316-2200A2C8-B39C-4DA5-8CE1-DA4526C96F27

Q35923316-23BCAE3C-365B-4050-8524-A52A6AAB1CD0

Q35923316-25C55389-395A-457B-871A-13F4567B1163

Q35923316-2C9DEFBE-CA08-417E-9A39-346A39C3FD27

P304

Q35923316-8C96F678-4B00-4224-AF46-E4C5DFC8EBF6

P31

Q35923316-427AF2A9-86D4-4608-B6F1-1BB5AB1DFB26

P356

Q35923316-F60BAAE7-2C74-4525-A72D-12D8C607C664

P433

Q35923316-D6459857-23F2-442C-8197-8E4D5E1914E2

P478

Q35923316-8C2BAF1D-014D-48BE-8BF9-06A671D9BFD7

P577

Q35923316-CDBDA43A-F4F9-4634-B8E3-058C39D2024A

P5875

Q35923316-EB4DCD81-1DBC-49C9-A6CE-10564E871814

P698

Q35923316-2FF9A963-D886-4CF3-8444-4DA9247D0445

P932

Q35923316-6C0F4CBE-72DA-4A6B-A39E-0AC6565C3564

P356

J.MATBIO.2012.02.006

P1433

P1476

Perlecan modulates VEGF signal ...... n endochondral bone formation.

@en

P2093

Eri Arikawa-Hirasawa

http://www.w3.org/2001/XMLSchema#string

Haruka Kaneko

http://www.w3.org/2001/XMLSchema#string

John R Hassell

http://www.w3.org/2001/XMLSchema#string

Keisuke Kosaki

http://www.w3.org/2001/XMLSchema#string

Kentaro Hozumi

http://www.w3.org/2001/XMLSchema#string

Muneaki Ishijima

http://www.w3.org/2001/XMLSchema#string

Nobuharu Suzuki

http://www.w3.org/2001/XMLSchema#string

Tomoya Matsunobu

http://www.w3.org/2001/XMLSchema#string

Yoshihiko Yamada

http://www.w3.org/2001/XMLSchema#string

P2860

Heparanase cleavage of perlecan heparan sulfate modulates FGF10 activity during ex vivo submandibular gland branching morphogenesis

Endorepellin, the angiostatic module of perlecan, interacts with both the α2β1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonism

Structural and functional mutations of the perlecan gene cause Schwartz-Jampel syndrome, with myotonic myopathy and chondrodysplasia

Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development

MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes

Perlecan regulates developmental angiogenesis by modulating the VEGF-VEGFR2 axis.

Perlecan maintains the integrity of cartilage and some basement membranes

Perlecan is essential for cartilage and cephalic development

Endorepellin, a novel inhibitor of angiogenesis derived from the C terminus of perlecan

Developmental expression of perlecan during murine embryogenesis

P304

234-245

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.MATBIO.2012.02.006

http://www.w3.org/2001/XMLSchema#string

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

31

http://www.w3.org/2001/XMLSchema#string

P577

2012-03-07T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

221708474

http://www.w3.org/2001/XMLSchema#string

P698

22421594

http://www.w3.org/2001/XMLSchema#string

P932

3340529

http://www.w3.org/2001/XMLSchema#string