SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance. - Test2 - elhamkhani - TriplyDB

SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance.

SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance.

http://www.wikidata.org/entity/Q35945054

about

Fundamentals of cancer metabolism MicroRNAs and oncogenic transcriptional regulatory networks controlling metabolic reprogramming in cancers Amino acid management in cancer T cell metabolism drives immunity Functional metabolomics: from biomarker discovery to metabolome reprogramming Alleviation of neuronal energy deficiency by mTOR inhibition as a treatment for mitochondria-related neurodegeneration Evidence from a large-scale meta-analysis indicates eczema reduces the incidence of glioma Magnetic Resonance (MR) Metabolic Imaging in Glioma.One-carbon metabolism and nucleotide biosynthesis as attractive targets for anticancer therapy.Nicotinamide metabolism regulates glioblastoma stem cell maintenance.Pediatric high-grade glioma: biologically and clinically in need of new thinking Essential Function of the Serine Hydroxymethyl Transferase (SHMT) Gene During Rapid Syncytial Cell Cycles in Drosophila.A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate.Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway Cancer's Fuel Choice: New Flavors for a Picky Eater MERAV: a tool for comparing gene expression across human tissues and cell types.Alterations in cellular metabolome after pharmacological inhibition of Notch in glioblastoma cells.Targeting One Carbon Metabolism with an Antimetabolite Disrupts Pyrimidine Homeostasis and Induces Nucleotide Overflow.Label-Free Neurosurgical Pathology with Stimulated Raman Imaging.Targeting MTHFD2 in acute myeloid leukemia The importance of serine metabolism in cancer Metabolic requirements for cancer cell proliferation Distinctly perturbed metabolic networks underlie differential tumor tissue damages induced by immune modulator β-glucan in a two-case ex vivo non-small-cell lung cancer study.The platelet isoform of phosphofructokinase contributes to metabolic reprogramming and maintains cell proliferation in clear cell renal cell carcinoma.Glycine supplementation in vitro enhances porcine preimplantation embryo cell number and decreases apoptosis but does not lead to live births.TTBK2 circular RNA promotes glioma malignancy by regulating miR-217/HNF1β/Derlin-1 pathway.NF-Y activates genes of metabolic pathways altered in cancer cells.Metabolic reprogramming in glioblastoma: the influence of cancer metabolism on epigenetics and unanswered questions One-carbon metabolism in cancer.Tumor suppressors microRNA-302d and microRNA-16 inhibit human glioblastoma multiforme by targeting NF-κB and FGF2.Targeting metabolic reprogramming in KRAS-driven cancers.Identification of TWIST-interacting genes in prostate cancer.Mitochondria and Cancer.Glycine decarboxylase and HIF-1α expression are negative prognostic factors in primary resected early-stage non-small cell lung cancer.Spheroid cancer stem cells display reprogrammed metabolism and obtain energy by actively running the tricarboxylic acid (TCA) cycle Give it or take it: the flux of one-carbon in cancer cells.The role of glycine in regulated cell death.miR-615-5p prevents proliferation and migration through negatively regulating serine hydromethyltransferase 2 (SHMT2) in hepatocellular carcinoma.Targeting cancer stem-like cells in glioblastoma and colorectal cancer through metabolic pathways.One-Carbon Metabolism in Health and Disease.

P2860

Q26744062-F573DF6F-F51A-45A9-BD7D-127AEB88D794 Q26745980-022626FF-09CF-4FAB-A79B-251386172B67 Q26798087-7428F5C5-4070-400B-B328-2BE6FF6DB0C3 Q26799575-DC10C0BB-CB98-470F-BF30-7998AB9B6771 Q28610979-6C157B7E-56C4-4367-A06F-E1B50CBA14F8 Q28834138-39BEBCE2-706A-4412-BD55-918F092E78E6 Q29248257-6D00C218-8789-4D5D-B56E-FEA2A9F938C2 Q31015256-5AA08E3D-26D0-4FF0-86A6-CC4D955A8274 Q33618935-77C0968D-E844-426C-A197-8D1A6D43803A Q33703205-D13AD557-0864-4ACD-9024-B34669032907 Q33777868-6140DF0F-133C-4E04-B5B9-8EC0D8214A0A Q33877374-1E50980F-988B-456A-9068-B0FB760B515A Q35998002-DB0AD3A0-2E0F-4ABD-8DA6-4B8E65DDC0F0 Q36025884-5A573001-D824-4A3F-A8E4-B2581CB2E459 Q36365703-BCA5CD1E-712C-44A3-9C08-2849D092A146 Q36435039-23E9ED49-CDE3-4B91-94C2-A821E94A1527 Q36633528-D544B0C1-9EFA-4C09-8774-9ABB9497C155 Q37008970-A4D4CA43-048E-4B76-85D0-0EFCCFD8A3DF Q37014028-ABE04E16-F0CD-4E3D-9EAD-936E0D835E22 Q37047306-26AF3363-D546-47BA-A19F-AAA1AAD20128 Q37145927-35B01B9C-5A4E-4F35-B938-7DB1D2C975CD Q37185238-FCA413EE-1533-4FFF-8915-338E84E90DAC Q37188669-A845D2C7-9206-4113-8079-213937573534 Q37317189-F9918EF3-B46C-49AE-A08D-6347C7554767 Q37345799-11662297-4F1F-4966-BF23-6BBA839419BC Q37655453-161F2552-DDEA-4EFD-B21D-33BC8D70D137 Q38294889-3D76C696-0262-4094-84B1-23228E1C7528 Q38548208-3E223933-DA23-4C60-86D9-4F20EBC24A5F Q38687639-25883B35-933A-44BE-8C65-762D2E331A3E Q38703769-84DE28B0-FC7C-412E-B0C9-E8DB9FF5D82A Q38710288-F7D93DA9-280B-4983-B9AA-D77CB2B110E0 Q38719560-13785489-BD52-4A9B-8983-2AB4C7340BEC Q38760551-6295C52E-2BCD-4930-AD5A-74A071640F07 Q38773668-2875390D-D8EF-4D39-92A0-8E81534DD1A7 Q38775029-CCC41CFF-408A-4405-92B7-FCC49DF0F4B0 Q38797533-97EBF0F0-4679-4D9D-BAB3-5F190FE4F213 Q38804933-5463E048-FB01-4C9A-9B30-4B7689989619 Q38812064-A5A4DF63-3B26-4299-9248-87D725098931 Q38889490-F69EAA36-9151-40EA-8DCA-45ADF6481FBA Q38957946-1B1D0369-6C32-40C6-84AB-8FE1960DF272

P2860

SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance.

http://www.wikidata.org/entity/Q35945054

description

2015 nî lūn-bûn

@nan

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

2015年论文

@zh

2015年论文

@zh-cn

name

SHMT2 drives glioma cell survi ...... pendence on glycine clearance.

@ast

SHMT2 drives glioma cell survi ...... pendence on glycine clearance.

@en

type

label

SHMT2 drives glioma cell survi ...... pendence on glycine clearance.

@ast

SHMT2 drives glioma cell survi ...... pendence on glycine clearance.

@en

prefLabel

SHMT2 drives glioma cell survi ...... pendence on glycine clearance.

@ast

SHMT2 drives glioma cell survi ...... pendence on glycine clearance.

@en

P1433

Q35945054-14245AEC-AF62-4811-BC76-BC9A20553BB2

P1476

Q35945054-1CB59E7C-867B-45C8-A9CB-D1C7D7581A28

P2093

Q35945054-17E5C243-67C7-449D-90F6-C44F57A39B9F

Q35945054-26060282-4CAA-4B08-B63D-E4B566FA282E

Q35945054-2C8C81D9-E250-4154-9CBE-6860E6B54CAB

Q35945054-2FDAFA6F-34CF-40B2-AFD4-673DF7279925

Q35945054-53C9C472-9EC3-401B-97A8-DB1F858D3CA9

Q35945054-55AB7844-58CE-4440-80D4-27AD6C3AA3CE

Q35945054-5DBE0A97-B12F-44DB-BB42-4AD88220EACF

Q35945054-8D7224B4-6C03-46E8-9CE4-9E344B3C86C9

Q35945054-AFD91BE6-8025-48E4-AF3D-DBAC5C97B847

Q35945054-B7DA1B9B-C222-4811-AF2E-6E9D8BC3A67C

P2860

Q35945054-0A16601F-F6AB-4594-85B3-91A7DE004750

Q35945054-0B676A3E-24C4-49E2-923B-80833ACC2BE2

Q35945054-179DBB1C-32CF-4B98-944E-03C4620FC17D

Q35945054-221EF377-7991-423C-8540-0AA27A0BFD44

Q35945054-28B1EEDC-0DE3-47FD-BC54-A7D22FDC1860

Q35945054-2E676B3C-968B-4A59-9748-BE22F0A70604

Q35945054-31E6EC50-8110-4FC0-A65A-1CA9E0BAD906

Q35945054-349ED3B3-DD07-4333-86A6-754C2616AC95

Q35945054-3944F963-B688-4CCB-B13B-B832D24828E1

Q35945054-3975996C-BB1B-4087-B883-371B00E9E2C3

P2888

Q35945054-16C7B526-CA7F-4776-81E9-48D9F15F25C6

P304

Q35945054-FD522938-C52F-42A6-9E8A-D996FB1CEC41

P31

Q35945054-8CABD711-3930-42C2-B484-B2E3F06006A1

P356

Q35945054-28FF9193-796F-4F48-A871-F4F8DAD5E8C2

P407

Q35945054-BB4BB21D-C089-4141-8870-3EEC699FAEC5

P433

Q35945054-F314112C-3C0A-457D-AB80-76F315A97ADA

P478

Q35945054-1C794C8E-4129-4675-A518-B58C94F4BD99

P50

Q35945054-124E8529-8E33-4FF2-9D84-5C832A1D447C

Q35945054-8A37AA3F-4E34-4604-A911-B75D70424029

Q35945054-B3626F97-66AE-417C-9855-60B671FE2B36

Q35945054-F00DE013-36D1-441D-956E-147D77985DF6

P577

Q35945054-17B25BFD-A5B1-4989-9BCC-8BA97AFDD58A

P5875

Q35945054-F5669979-22ED-439F-B21A-588D47CDC57A

P698

Q35945054-A880B750-B86F-4311-95A8-10670AD9DCF0

P932

Q35945054-500FBEF2-4545-4947-BC12-8E8BC8F5FD6E

P356

P1433

P1476

SHMT2 drives glioma cell survi ...... ependence on glycine clearance

@en

P2093

Brian P Fiske

http://www.w3.org/2001/XMLSchema#string

Dan Y Gui

http://www.w3.org/2001/XMLSchema#string

Dohoon Kim

http://www.w3.org/2001/XMLSchema#string

Elizaveta Freinkman

http://www.w3.org/2001/XMLSchema#string

Jason R Cantor

http://www.w3.org/2001/XMLSchema#string

Keith L Ligon

http://www.w3.org/2001/XMLSchema#string

Kenjiro Kami

http://www.w3.org/2001/XMLSchema#string

Kivanc Birsoy

http://www.w3.org/2001/XMLSchema#string

Laura M Shelton

http://www.w3.org/2001/XMLSchema#string

Manjae Kwon

http://www.w3.org/2001/XMLSchema#string

P2860

Hypoxia and defective apoptosis drive genomic instability and tumorigenesis

Understanding the Warburg effect: the metabolic requirements of cell proliferation

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

Serine is a natural ligand and allosteric activator of pyruvate kinase M2

Stem cells, cancer, and cancer stem cells

ONCOMINE: a cancer microarray database and integrated data-mining platform

Exploiting tumour hypoxia in cancer treatment

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

The central nervous system-restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma

ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state

P2888

P304

363-367

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/NATURE14363

http://www.w3.org/2001/XMLSchema#string

P407

P433

7547

http://www.w3.org/2001/XMLSchema#string

P478

520

http://www.w3.org/2001/XMLSchema#string

P50

Richard Possemato

David M Sabatini

P577

2015-04-08T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

274726250

http://www.w3.org/2001/XMLSchema#string

P698

25855294

http://www.w3.org/2001/XMLSchema#string

P932

4533874

http://www.w3.org/2001/XMLSchema#string