Ectopic restriction of DNA repair reveals that UNG2 excises AID-induced uracils predominantly or exclusively during G1 phase
about
Mutations, kataegis and translocations in B cells: understanding AID promiscuous activityIgH chain class switch recombination: mechanism and regulationATAD5 deficiency decreases B cell division and Igh recombinationProximity to AGCT sequences dictates MMR-independent versus MMR-dependent mechanisms for AID-induced mutation via UNG2.Refining the Neuberger model: Uracil processing by activated B cells.Uracil excision by endogenous SMUG1 glycosylase promotes efficient Ig class switching and impacts on A:T substitutions during somatic mutationRPA accumulation during class switch recombination represents 5'-3' DNA-end resection during the S-G2/M phase of the cell cycleNbs1 ChIP-Seq Identifies Off-Target DNA Double-Strand Breaks Induced by AID in Activated Splenic B Cells.Cell Cycle Regulates Nuclear Stability of AID and Determines the Cellular Response to AID.Mutagenesis by AID: Being in the Right Place at the Right Time.Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolutionA regulatory role for the cohesin loader NIPBL in nonhomologous end joining during immunoglobulin class switch recombination.DNA polymerases β and λ do not directly affect Ig variable region somatic hypermutation although their absence reduces the frequency of mutations.Pms2 and uracil-DNA glycosylases act jointly in the mismatch repair pathway to generate Ig gene mutations at A-T base pairs.Mismatch repair proteins and AID activity are required for the dominant negative function of C-terminally deleted AID in class switching.SAMHD1 enhances immunoglobulin hypermutation by promoting transversion mutation.RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination.
P2860
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P2860
Ectopic restriction of DNA repair reveals that UNG2 excises AID-induced uracils predominantly or exclusively during G1 phase
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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name
Ectopic restriction of DNA rep ...... or exclusively during G1 phase
@ast
Ectopic restriction of DNA rep ...... or exclusively during G1 phase
@en
type
label
Ectopic restriction of DNA rep ...... or exclusively during G1 phase
@ast
Ectopic restriction of DNA rep ...... or exclusively during G1 phase
@en
prefLabel
Ectopic restriction of DNA rep ...... or exclusively during G1 phase
@ast
Ectopic restriction of DNA rep ...... or exclusively during G1 phase
@en
P2093
P2860
P356
P1476
Ectopic restriction of DNA rep ...... or exclusively during G1 phase
@en
P2093
Adrian L Smith
Christine W Y Yee
Christopher J Jolly
George Sharbeen
P2860
P304
P356
10.1084/JEM.20112379
P407
P577
2012-04-23T00:00:00Z