A DOUBLETIME kinase binding domain on the Drosophila PERIOD protein is essential for its hyperphosphorylation, transcriptional repression, and circadian clock function.
about
Activating PER repressor through a DBT-directed phosphorylation switchNEMO/NLK phosphorylates PERIOD to initiate a time-delay phosphorylation circuit that sets circadian clock speedCircadian organization of behavior and physiology in DrosophilaDOUBLETIME plays a noncatalytic role to mediate CLOCK phosphorylation and repress CLOCK-dependent transcription within the Drosophila circadian clockDrosophila and vertebrate casein kinase Idelta exhibits evolutionary conservation of circadian functionA small conserved domain of Drosophila PERIOD is important for circadian phosphorylation, nuclear localization, and transcriptional repressor activityTranslational regulation of the DOUBLETIME/CKIδ/ε kinase by LARK contributes to circadian period modulationThe CK2 kinase stabilizes CLOCK and represses its activity in the Drosophila circadian oscillatorCooperative interaction between phosphorylation sites on PERIOD maintains circadian period in DrosophilaRhythmic PER abundance defines a critical nodal point for negative feedback within the circadian clock mechanismCodon usage affects the structure and function of the Drosophila circadian clock protein PERIOD.G protein-coupled receptor kinase 2 is required for rhythmic olfactory responses in Drosophila.Dominant-negative CK2alpha induces potent effects on circadian rhythmicityCircadian transcription contributes to core period determination in Drosophila.Dynamic PER repression mechanisms in the Drosophila circadian clock: from on-DNA to off-DNA.Sleep triggered by an immune response in Drosophila is regulated by the circadian clock and requires the NFkappaB RelishPhosphorylation of the transcription activator CLOCK regulates progression through a ∼ 24-h feedback loop to influence the circadian period in Drosophila.Molecular genetic analysis of circadian timekeeping in Drosophila.Phosphorylation of a central clock transcription factor is required for thermal but not photic entrainment.A hierarchical phosphorylation cascade that regulates the timing of PERIOD nuclear entry reveals novel roles for proline-directed kinases and GSK-3beta/SGG in circadian clocks.A role for timely nuclear translocation of clock repressor proteins in setting circadian clock speedCULLIN-3 controls TIMELESS oscillations in the Drosophila circadian clockTwo distinct modes of PERIOD recruitment onto dCLOCK reveal a novel role for TIMELESS in circadian transcription.Of switches and hourglasses: regulation of subcellular traffic in circadian clocks by phosphorylation.Mechanism of the Neurospora circadian clock, a FREQUENCY-centric view.Natural variation in the Drosophila melanogaster clock gene period modulates splicing of its 3'-terminal intron and mid-day siesta.A Doubletime Nuclear Localization Signal Mediates an Interaction with Bride of Doubletime to Promote Circadian Function.TIMELESS is an important mediator of CK2 effects on circadian clock function in vivoThe novel gene twenty-four defines a critical translational step in the Drosophila clock.Functional analysis of Casein Kinase 1 in a minimal circadian systemFunctional analysis of the rodent CK1tau mutation in the circadian clock of a marine unicellular alga.A key temporal delay in the circadian cycle of Drosophila is mediated by a nuclear localization signal in the timeless protein.The Catalytic and Non-catalytic Functions of the Brahma Chromatin-Remodeling Protein Collaborate to Fine-Tune Circadian Transcription in Drosophila.A role for O-GlcNAcylation in setting circadian clock speedProtein kinase A and casein kinases mediate sequential phosphorylation events in the circadian negative feedback loopIdentification of Light-Sensitive Phosphorylation Sites on PERIOD That Regulate the Pace of Circadian Rhythms in DrosophilaThe phospho-occupancy of an atypical SLIMB-binding site on PERIOD that is phosphorylated by DOUBLETIME controls the pace of the clock.Control of WHITE COLLAR localization by phosphorylation is a critical step in the circadian negative feedback process.A PER/TIM/DBT interval timer for Drosophila's circadian clock.Posttranslational control of the Neurospora circadian clock.
P2860
Q21145851-17840968-E463-43FB-869C-DDC775598EF4Q24594785-6E2F2F30-C261-47C9-A2E3-6394D4437A4DQ24633391-C0404884-2EA3-47B9-93F1-5BF24C44721AQ24647875-FD5C3248-7623-45CD-84F3-702385AA2A20Q24650809-2EE3349C-477A-4E95-9645-E46BBABAFC97Q24676014-0F70A1EB-CC31-46A6-B192-4554FF2B204CQ27314601-FA8DB576-8F53-49B8-9F33-C14D6224DAE3Q27316942-465AABEB-D0B2-4490-B9D9-688C339B892BQ28533842-B5AAD9B6-0D51-4F14-87B1-42341D45D7ADQ28588540-B04EE515-063B-4B87-BB86-151CA9EED0FBQ30392005-E1CAC09A-691A-461C-9C56-BBDFBB0F4385Q30489237-64C0728E-0F80-46BF-8264-48DAD550D1E7Q33315572-696EA913-5B68-4AB2-A275-F3A130904C6DQ33336761-1463B2B2-FA56-4824-8BE6-3D88A87550C4Q33631146-6D4345ED-6011-4E69-BBDC-C6B606D48A5CQ33698725-719586A2-A710-4287-AEBC-1B5C99EF8F68Q33888611-5697F4DC-24C3-4CAA-A537-B7A7FD926E3AQ33938983-E237D103-27D1-4196-9564-781D4B68A76AQ34046400-7EF3D421-E5E4-47BB-82EE-6867F1442E1CQ34213033-96481025-C089-4C9C-A4DC-0386565581FAQ34241551-2538E882-C42B-423B-A772-0F7853CC159CQ34373827-FEA2A5EB-3098-4B03-8B30-7EEEA221E9ABQ34383953-98669453-702E-482A-B89D-EBE3FC4F1A5EQ34394835-54A866DE-5625-405C-AB1D-029D42C600C9Q34442830-B112A191-1FAE-40DC-A54A-AF21F160A89AQ34478044-F656CECD-93B2-4844-B945-BB202B0F294AQ34481028-7A298AD3-4619-4924-B61D-E5BD0C8F1C7DQ34545793-1B9845CA-E76D-42B6-AD99-BC1720CA1495Q34776644-415B9537-CD70-4F9D-A525-6BACE6FF3908Q34921771-24306D14-2EDD-4195-8B13-A570FCF8C9F3Q35017658-FFEC8088-C108-4CF1-87F7-41BD77957A51Q35222744-B692655C-E5B0-42B9-96C5-F746833154BDQ35680069-E4E8107E-7472-4E68-ABED-7A988A6E28BEQ35835224-895D2849-2268-46EE-8935-9D1B528D3C69Q36209723-7F172393-06A2-4ED1-95DE-7F1A0D6C5178Q36736190-1D6DF45A-68F3-4C52-AF6F-75B9D16A3B2BQ36802821-5F986F56-1085-4740-930B-6C74C7F27767Q37028231-4E74DB4A-9F9E-4486-8C01-6DF6091BF5F2Q37140959-5CBCD722-4A47-4F4A-BB9F-7B635B52BD5AQ37141000-B8A0F8E8-4FA7-494C-BFB3-2BC846188B92
P2860
A DOUBLETIME kinase binding domain on the Drosophila PERIOD protein is essential for its hyperphosphorylation, transcriptional repression, and circadian clock function.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
A DOUBLETIME kinase binding do ...... and circadian clock function.
@ast
A DOUBLETIME kinase binding do ...... and circadian clock function.
@en
type
label
A DOUBLETIME kinase binding do ...... and circadian clock function.
@ast
A DOUBLETIME kinase binding do ...... and circadian clock function.
@en
prefLabel
A DOUBLETIME kinase binding do ...... and circadian clock function.
@ast
A DOUBLETIME kinase binding do ...... and circadian clock function.
@en
P2093
P2860
P356
P1476
A DOUBLETIME kinase binding do ...... and circadian clock function.
@en
P2093
Eun Young Kim
Hyuk Wan Ko
Isaac Edery
Paul E Hardin
Wangjie Yu
P2860
P304
P356
10.1128/MCB.02339-06
P407
P577
2007-04-23T00:00:00Z