Stable differentiation and clonality of murine long-term hematopoiesis after extended reduced-intensity selection for MGMT P140K transgene expression.
about
Towards in vivo amplification: Overcoming hurdles in the use of hematopoietic stem cells in transplantation and gene therapyCell-intrinsic and vector-related properties cooperate to determine the incidence and consequences of insertional mutagenesis.Imaging stem cell-derived persistent foci after in vivo selection of lentiviral MGMT-P140K transduced murine bone marrow cells.Extensive methylation of promoter sequences silences lentiviral transgene expression during stem cell differentiation in vivo.The tRNA methyltransferase Dnmt2 is required for accurate polypeptide synthesis during haematopoiesis.Chemoselection of allogeneic HSC after murine neonatal transplantation without myeloablation or post-transplant immunosuppression.Modulation of radiation-induced life shortening by systemic intravenous MnSOD-plasmid liposome gene therapyLong-term polyclonal and multilineage engraftment of methylguanine methyltransferase P140K gene-modified dog hematopoietic cells in primary and secondary recipientsAmelioration of murine beta-thalassemia through drug selection of hematopoietic stem cells transduced with a lentiviral vector encoding both gamma-globin and the MGMT drug-resistance gene.Reciprocal relationship between O6-methylguanine-DNA methyltransferase P140K expression level and chemoprotection of hematopoietic stem cells.
P2860
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P2860
Stable differentiation and clonality of murine long-term hematopoiesis after extended reduced-intensity selection for MGMT P140K transgene expression.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
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2007年论文
@zh-cn
name
Stable differentiation and clo ...... MT P140K transgene expression.
@ast
Stable differentiation and clo ...... MT P140K transgene expression.
@en
type
label
Stable differentiation and clo ...... MT P140K transgene expression.
@ast
Stable differentiation and clo ...... MT P140K transgene expression.
@en
prefLabel
Stable differentiation and clo ...... MT P140K transgene expression.
@ast
Stable differentiation and clo ...... MT P140K transgene expression.
@en
P2093
P2860
P1433
P1476
Stable differentiation and clo ...... MT P140K transgene expression.
@en
P2093
David A Williams
Hanno Glimm
Ingo H Pilz
Manfred Schmidt
Sylvia Fessler
P2860
P304
P356
10.1182/BLOOD-2006-11-053710
P407
P577
2007-05-11T00:00:00Z