Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A. - Test2 - elhamkhani - TriplyDB

Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A.

Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A.

http://www.wikidata.org/entity/Q36003000

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The broken "Off" switch in cancer signaling: PP2A as a regulator of tumorigenesis, drug resistance, and immune surveillance Advances in Autophagy Regulatory Mechanisms Autophagy, Metabolism, and Cancer The Proteasome Inhibitor Bortezomib Affects Chondrosarcoma Cells via the Mitochondria-Caspase Dependent Pathway and Enhances Death Receptor Expression and Autophagy Nutrient-regulated Phosphorylation of ATG13 Inhibits Starvation-induced Autophagy Activator of G-Protein Signaling 3-Induced Lysosomal Biogenesis Limits Macrophage Intracellular Bacterial Infection.Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells.Recent insights into the function of autophagy in cancer.Cancer-associated Fibroblasts Promote Irradiated Cancer Cell Recovery Through Autophagy.The protein restriction mimetic Resveratrol is an autophagy inducer stronger than amino acid starvation in ovarian cancer cells.Inositide-dependent signaling pathways as new therapeutic targets in myelodysplastic syndromes.Roles of autophagy and metabolism in pancreatic cancer cell adaptation to environmental challenges.Proteinuria causes dysfunctional autophagy in the proximal tubule.PHD2 Targeting Overcomes Breast Cancer Cell Death upon Glucose Starvation in a PP2A/B55α-Mediated Manner.Autophagy in cancer metastasis.Endoplasmic reticulum stress in the regulation of liver diseases: Involvement of Regulated IRE1α and β-dependent decay and miRNA.Mechanisms of Autophagy Initiation.Autophagy: machinery and regulation Fine-tuning of ULK1 mRNA and protein levels is required for autophagy oscillation.[Pemetrexed + Sorafenib] lethality is increased by inhibition of ERBB1/2/3-PI3K-NFκB compensatory survival signaling.Fasting-induced hormonal regulation of lysosomal function.A reversible phospho-switch mediated by ULK1 regulates the activity of autophagy protease ATG4B.Leucine induced dephosphorylation of Sestrin2 promotes mTORC1 activation.Dual targeting of androgen receptor and mTORC1 by salinomycin in prostate cancer.Identification of PPM1D as an essential Ulk1 phosphatase for genotoxic stress-induced autophagy.Beclin1 and HMGB1 ameliorate the α-synuclein-mediated autophagy inhibition in PC12 cells.The metabolic cross-talk between epithelial cancer cells and stromal fibroblasts in ovarian cancer progression: Autophagy plays a role.Targeted elimination of senescent Ras-transformed cells by suppression of MEK/ERK pathway.PP2A mediates apoptosis or autophagic cell death in multiple myeloma cell lines.PP2A as the Main Node of Therapeutic Strategies and Resistance Reversal in Triple-Negative Breast Cancer.The mammalian ULK1 complex and autophagy initiation.mTORC1 as the main gateway to autophagy.Phosphoglycerate Kinase 1 Phosphorylates Beclin1 to Induce Autophagy.A Molecular Perspective of Mammalian Autophagosome Biogenesis.Biological Roles of Alternative Autophagy.The serine/threonine protein phosphatase 2A controls autoimmunity.mTOR independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition.AMPK inhibits ULK1-dependent autophagosome formation and lysosomal acidification via distinct mechanisms.Rapamycin Enhances Repressed Autophagy and Attenuates Aggressive Progression in a Rat Model of IgA Nephropathy.Common Traits Spark the Mitophagy/Xenophagy Interplay

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Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A.

http://www.wikidata.org/entity/Q36003000

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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name

Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A.

@ast

Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A.

@en

type

label

Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A.

@ast

Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A.

@en

prefLabel

Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A.

@ast

Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A.

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Nature Communications

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Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A

@en

P2093

Junru Wang

http://www.w3.org/2001/XMLSchema#string

Rong Shi

http://www.w3.org/2001/XMLSchema#string

Xuejun Jiang

http://www.w3.org/2001/XMLSchema#string

Yan Feng

http://www.w3.org/2001/XMLSchema#string

P2860

A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

Structure of protein phosphatase 2A core enzyme bound to tumor-inducing toxins

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy

DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

The protein kinase complement of the human genome

Structure of the protein phosphatase 2A holoenzyme

Mammalian autophagy: core molecular machinery and signaling regulation

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

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8048

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10.1038/NCOMMS9048

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6

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2015-08-27T00:00:00Z

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