Epigenetic reprogramming of cancer cells via targeted DNA methylation. - Test2 - elhamkhani - TriplyDB

Epigenetic reprogramming of cancer cells via targeted DNA methylation.

Epigenetic reprogramming of cancer cells via targeted DNA methylation.

http://www.wikidata.org/entity/Q36012682

about

Enabling functional genomics with genome engineering Strategies for precision modulation of gene expression by epigenome editing: an overview The complexity of epigenetic diseases Epigenome engineering in cancer: fairytale or a realistic path to the clinic?The epigenome: the next substrate for engineering Editing the Neuronal Genome: a CRISPR View of Chromatin Regulation in Neuronal Development, Function, and Plasticity CRISPR-Cas9: Tool for Qualitative and Quantitative Plant Genome Editing Epigenetic Editing: On the Verge of Reprogramming Gene Expression at Will Chromatin regulation at the frontier of synthetic biology Local chromatin microenvironment determines DNMT activity: from DNA methyltransferase to DNA demethylase or DNA dehydroxymethylase Epigenomics and allergic disease Targeted methylation of the epithelial cell adhesion molecule (EpCAM) promoter to silence its expression in ovarian cancer cells Targeted DNA methylation in pericentromeres with genome editing-based artificial DNA methyltransferase.TGF-β mediated DNA methylation in prostate cancer.Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers.Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies.Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation.Complementation between inactive fragments of SssI DNA methyltransferase.Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins.Induced DNA demethylation by targeting Ten-Eleven Translocation 2 to the human ICAM-1 promoter.New approaches to manipulating the epigenome.Writing and rewriting the epigenetic code of cancer cells: from engineered proteins to small molecules Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma.Epigenetics of discordant monozygotic twins: implications for disease Can genome engineering be used to target cancer-associated enhancers?Current and upcoming approaches to exploit the reversibility of epigenetic mutations in breast cancer.Directed evolution of improved zinc finger methyltransferases.Predicting genome-wide DNA methylation using methylation marks, genomic position, and DNA regulatory elements.Genetically engineered pig models for human diseases.TALE-mediated epigenetic suppression of CDKN2A increases replication in human fibroblasts.Manipulation of prostate cancer metastasis by locus-specific modification of the CRMP4 promoter region using chimeric TALE DNA methyltransferase and demethylase.TALEored Epigenetics: A DNA-Binding Scaffold for Programmable Epigenome Editing and Analysis.Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer Prolonged re-expression of the hypermethylated gene EPB41L3 using artificial transcription factors and epigenetic drugs Stable oncogenic silencing in vivo by programmable and targeted de novo DNA methylation in breast cancer.P16-specific DNA methylation by engineered zinc finger methyltransferase inactivates gene transcription and promotes cancer metastasis.Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements Epigenetic Editing: targeted rewriting of epigenetic marks to modulate expression of selected target genes.Predicting DNA Methylation State of CpG Dinucleotide Using Genome Topological Features and Deep Networks.Breaking through an epigenetic wall: re-activation of Oct4 by KRAB-containing designer zinc finger transcription factors.

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Epigenetic reprogramming of cancer cells via targeted DNA methylation.

http://www.wikidata.org/entity/Q36012682

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Epigenetic reprogramming of cancer cells via targeted DNA methylation.

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Epigenetic reprogramming of cancer cells via targeted DNA methylation.

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type

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Epigenetic reprogramming of cancer cells via targeted DNA methylation.

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Epigenetic reprogramming of cancer cells via targeted DNA methylation.

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prefLabel

Epigenetic reprogramming of cancer cells via targeted DNA methylation.

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Epigenetic reprogramming of cancer cells via targeted DNA methylation.

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P1476

Epigenetic reprogramming of cancer cells via targeted DNA methylation

@en

P2093

Adriana S Beltran

http://www.w3.org/2001/XMLSchema#string

Ashley G Rivenbark

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Marianne G Rots

http://www.w3.org/2001/XMLSchema#string

Sabine Stolzenburg

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Xinni Yuan

http://www.w3.org/2001/XMLSchema#string

P2860

DNA methylation patterns and epigenetic memory

The molecular mechanism governing the oncogenic potential of SOX2 in breast cancer

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

UHRF1 plays a role in maintaining DNA methylation in mammalian cells

Bisulfite genomic sequencing: systematic investigation of critical experimental parameters

Krüppel-associated boxes are potent transcriptional repression domains

Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks

A rapid, generally applicable method to engineer zinc fingers illustrated by targeting the HIV-1 promoter

Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5'-GNN-3' DNA target sequences

Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A

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350-360

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scholarly article

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10.4161/EPI.19507

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4

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7

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Pilar Blancafort

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2012-04-01T00:00:00Z

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221896695

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22419067

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P921

DNA methylation

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3368819

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