about
Characterization of the DNA binding specificity of Shelterin complexesMolecular biology of lung cancer: clinical implicationsRoles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapiesEvolving Therapeutic Strategies for the Classic Philadelphia-Negative Myeloproliferative NeoplasmsTelomerase inhibitor Imetelstat (GRN163L) limits the lifespan of human pancreatic cancer cellsAlternative lengthening of telomeres can be maintained by preferential elongation of lagging strands.Telomere maintenance mechanisms in cancer: clinical implicationsTranscriptional coactivator CBP upregulates hTERT expression and tumor growth and predicts poor prognosis in human lung cancersAlteration of histone acetylation pattern during long-term serum-free culture conditions of human fetal placental mesenchymal stem cells.The OB-fold domain 1 of human POT1 recognizes both telomeric and non-telomeric DNA motifsPreventing clonal evolutionary processes in cancer: Insights from mathematical models.Targeted therapies for lung cancer: clinical experience and novel agentsQuantifying replicative senescence as a tumor suppressor pathway and a target for cancer therapyTelomerase activity assay for the diagnosis of malignant pleural effusion: A meta-analysis.Switch telomerase to ALT mechanism by inducing telomeric DNA damages and dysfunction of ATRX and DAXX.The Na+/I- symporter (NIS): mechanism and medical impact.Telomerase-independent paths to immortality in predictable cancer subtypes.Optimization and preclinical design of genetically engineered viruses for human oncolytic therapy.Telomere maintenance in soft tissue sarcomasBeyond Telomerase: Telomere Instability as a Novel Target for Cancer Therapy.Synthesis and biological evaluation of hybrid acridine-HSP90 ligand conjugates as telomerase inhibitors.Friend or foe? Telomerase as a pharmacological target in cancer and cardiovascular disease.New strategies in myelofibrosis: the evolving paradigm of disease pathogenesis, prognostication and treatment.Telomerase inhibition improves tumor response to radiotherapy in a murine orthotopic model of human glioblastoma.Inhibitors of telomerase and poly(ADP-ribose) polymerases synergize to limit the lifespan of pancreatic cancer cells.Chemistry, mechanism and clinical status of antisense oligonucleotides and duplex RNAs.Cancer. Cancer and telomeres--an ALTernative to telomerase.Imetelstat, a telomerase inhibitor, is capable of depleting myelofibrosis stem and progenitor cells
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Targeting telomerase-expressing cancer cells.
@ast
Targeting telomerase-expressing cancer cells.
@en
type
label
Targeting telomerase-expressing cancer cells.
@ast
Targeting telomerase-expressing cancer cells.
@en
prefLabel
Targeting telomerase-expressing cancer cells.
@ast
Targeting telomerase-expressing cancer cells.
@en
P2860
P921
P1476
Targeting telomerase-expressing cancer cells.
@en
P2093
Jerry W Shay
Michel M Ouellette
P2860
P304
P356
10.1111/J.1582-4934.2011.01279.X
P577
2011-07-01T00:00:00Z