Comparison of parallel high-throughput RNA sequencing between knockout of TDP-43 and its overexpression reveals primarily nonreciprocal and nonoverlapping gene expression changes in the central nervous system of Drosophila
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Identification of genetic modifiers of TDP-43 neurotoxicity in DrosophilaMotor neuron expression of the voltage-gated calcium channel cacophony restores locomotion defects in a Drosophila, TDP-43 loss of function model of ALS.Drosophila lines with mutant and wild type human TDP-43 replacing the endogenous gene reveals phosphorylation and ubiquitination in mutant lines in the absence of viability or lifespan defects.TDP-1, the Caenorhabditis elegans ortholog of TDP-43, limits the accumulation of double-stranded RNA.A fruitful endeavor: modeling ALS in the fruit flyLinking RNA Dysfunction and Neurodegeneration in Amyotrophic Lateral Sclerosis.Drosophila TDP-43 RNA-Binding Protein Facilitates Association of Sister Chromatid Cohesion Proteins with Genes, Enhancers and Polycomb Response Elements.Disease animal models of TDP-43 proteinopathy and their pre-clinical applications.Next-generation sequencing in understanding complex neurological diseaseEmerging roles for hnRNPs in post-transcriptional regulation: what can we learn from flies?The Role of TDP-43 in Alzheimer's Disease.Splicing factors act as genetic modulators of TDP-43 production in a new autoregulatory TDP-43 Drosophila model.Restoration of motor defects caused by loss of Drosophila TDP-43 by expression of the voltage-gated calcium channel, Cacophony, in central neurons.TDP-43 affects splicing profiles and isoform production of genes involved in the apoptotic and mitotic cellular pathwaysRapamycin alleviates pathogenesis of a new Drosophila model of ALS-TDP.Reduced TDP-43 Expression Improves Neuronal Activities in a Drosophila Model of Perry Syndrome.Exploring the Interaction of Drosophila TDP-43 and the Type II Voltage-Gated Calcium Channel, Cacophony, in Regulating Motor Function and Behavior.Downregulation of glutamic acid decarboxylase in Drosophila TDP-43-null brains provokes paralysis by affecting the organization of the neuromuscular synapses.The role of TGF-β superfamily signaling in neurological disorders.Overexpression of ter94, Drosophila VCP, improves motor neuron degeneration induced by knockdown of TBPH, Drosophila TDP-43.
P2860
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P2860
Comparison of parallel high-throughput RNA sequencing between knockout of TDP-43 and its overexpression reveals primarily nonreciprocal and nonoverlapping gene expression changes in the central nervous system of Drosophila
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Comparison of parallel high-th ...... l nervous system of Drosophila
@ast
Comparison of parallel high-th ...... l nervous system of Drosophila
@en
type
label
Comparison of parallel high-th ...... l nervous system of Drosophila
@ast
Comparison of parallel high-th ...... l nervous system of Drosophila
@en
prefLabel
Comparison of parallel high-th ...... l nervous system of Drosophila
@ast
Comparison of parallel high-th ...... l nervous system of Drosophila
@en
P2093
P2860
P356
P1433
P1476
Comparison of parallel high-th ...... l nervous system of Drosophila
@en
P2093
Daniel L Lakeland
David B Morton
Jer-Cherng Chang
P2860
P304
P356
10.1534/G3.112.002998
P577
2012-07-01T00:00:00Z