Comparison of parallel high-throughput RNA sequencing between knockout of TDP-43 and its overexpression reveals primarily nonreciprocal and nonoverlapping gene expression changes in the central nervous system of Drosophila

Comparison of parallel high-throughput RNA sequencing between knockout of TDP-43 and its overexpression reveals primarily nonreciprocal and nonoverlapping gene expression changes in the central nervous system of Drosophila

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Identification of genetic modifiers of TDP-43 neurotoxicity in Drosophila Motor neuron expression of the voltage-gated calcium channel cacophony restores locomotion defects in a Drosophila, TDP-43 loss of function model of ALS.Drosophila lines with mutant and wild type human TDP-43 replacing the endogenous gene reveals phosphorylation and ubiquitination in mutant lines in the absence of viability or lifespan defects.TDP-1, the Caenorhabditis elegans ortholog of TDP-43, limits the accumulation of double-stranded RNA.A fruitful endeavor: modeling ALS in the fruit fly Linking RNA Dysfunction and Neurodegeneration in Amyotrophic Lateral Sclerosis.Drosophila TDP-43 RNA-Binding Protein Facilitates Association of Sister Chromatid Cohesion Proteins with Genes, Enhancers and Polycomb Response Elements.Disease animal models of TDP-43 proteinopathy and their pre-clinical applications.Next-generation sequencing in understanding complex neurological disease Emerging roles for hnRNPs in post-transcriptional regulation: what can we learn from flies?The Role of TDP-43 in Alzheimer's Disease.Splicing factors act as genetic modulators of TDP-43 production in a new autoregulatory TDP-43 Drosophila model.Restoration of motor defects caused by loss of Drosophila TDP-43 by expression of the voltage-gated calcium channel, Cacophony, in central neurons.TDP-43 affects splicing profiles and isoform production of genes involved in the apoptotic and mitotic cellular pathways Rapamycin alleviates pathogenesis of a new Drosophila model of ALS-TDP.Reduced TDP-43 Expression Improves Neuronal Activities in a Drosophila Model of Perry Syndrome.Exploring the Interaction of Drosophila TDP-43 and the Type II Voltage-Gated Calcium Channel, Cacophony, in Regulating Motor Function and Behavior.Downregulation of glutamic acid decarboxylase in Drosophila TDP-43-null brains provokes paralysis by affecting the organization of the neuromuscular synapses.The role of TGF-β superfamily signaling in neurological disorders.Overexpression of ter94, Drosophila VCP, improves motor neuron degeneration induced by knockdown of TBPH, Drosophila TDP-43.

P2860

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P2860

Comparison of parallel high-throughput RNA sequencing between knockout of TDP-43 and its overexpression reveals primarily nonreciprocal and nonoverlapping gene expression changes in the central nervous system of Drosophila

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http://www.wikidata.org/entity/Q36065980

description

2012 nî lūn-bûn

@nan

2012年の論文

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2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

Comparison of parallel high-th ...... l nervous system of Drosophila

@ast

Comparison of parallel high-th ...... l nervous system of Drosophila

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type

Item

label

Comparison of parallel high-th ...... l nervous system of Drosophila

@ast

Comparison of parallel high-th ...... l nervous system of Drosophila

@en

prefLabel

Comparison of parallel high-th ...... l nervous system of Drosophila

@ast

Comparison of parallel high-th ...... l nervous system of Drosophila

@en

P1433

P1476

Comparison of parallel high-th ...... l nervous system of Drosophila

@en

P2093

Daniel L Lakeland

http://www.w3.org/2001/XMLSchema#string

David B Morton

http://www.w3.org/2001/XMLSchema#string

Jer-Cherng Chang

http://www.w3.org/2001/XMLSchema#string

P2860

Mapping and quantifying mammalian transcriptomes by RNA-Seq

Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping

TDP43 is a human low molecular weight neurofilament (hNFL) mRNA-binding protein

Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs

TDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expression

Homophila: human disease gene cognates in Drosophila

BEHAVIORAL MUTANTS OF Drosophila ISOLATED BY COUNTERCURRENT DISTRIBUTION

Cluster analysis and display of genome-wide expression patterns

TDP-43 overexpression enhances exon 7 inclusion during the survival of motor neuron pre-mRNA splicing

Depletion of TDP 43 overrides the need for exonic and intronic splicing enhancers in the human apoA-II gene.

P304

789-802

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P31

scholarly article

P356

10.1534/G3.112.002998

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Dennis Hazelett

P577

2012-07-01T00:00:00Z

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P5875

230624665

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P698

22870402

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P921

Drosophila

overexpression

P932

3385985

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