Whole Exome Sequencing Reveals the Order of Genetic Changes during Malignant Transformation and Metastasis in a Single Patient with NF1-plexiform Neurofibroma
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Malignant Peripheral Nerve Sheath Tumors State of the Science: Leveraging Clinical and Biological Insights into Effective Therapies.Somatic loss of function mutations in neurofibromin 1 and MYC associated factor X genes identified by exome-wide sequencing in a wild-type GIST case.Whole Exome Sequencing of Rapid Autopsy Tumors and Xenograft Models Reveals Possible Driver Mutations Underlying Tumor ProgressionImmortalization of human normal and NF1 neurofibroma Schwann cells.The primacy of NF1 loss as the driver of tumorigenesis in neurofibromatosis type 1-associated plexiform neurofibromas.Loss of H3K27 tri-methylation is a diagnostic marker for malignant peripheral nerve sheath tumors and an indicator for an inferior survival.Spatially- and temporally-controlled postnatal p53 knockdown cooperates with embryonic Schwann cell precursor Nf1 gene loss to promote malignant peripheral nerve sheath tumor formation
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P2860
Whole Exome Sequencing Reveals the Order of Genetic Changes during Malignant Transformation and Metastasis in a Single Patient with NF1-plexiform Neurofibroma
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Whole Exome Sequencing Reveals ...... ith NF1-plexiform Neurofibroma
@ast
Whole Exome Sequencing Reveals ...... ith NF1-plexiform Neurofibroma
@en
type
label
Whole Exome Sequencing Reveals ...... ith NF1-plexiform Neurofibroma
@ast
Whole Exome Sequencing Reveals ...... ith NF1-plexiform Neurofibroma
@en
prefLabel
Whole Exome Sequencing Reveals ...... ith NF1-plexiform Neurofibroma
@ast
Whole Exome Sequencing Reveals ...... ith NF1-plexiform Neurofibroma
@en
P2093
P2860
P1476
Whole Exome Sequencing Reveals ...... ith NF1-plexiform Neurofibroma
@en
P2093
Angela C Hirbe
Arie Perry
Christopher A Miller
Eric J Duncavage
Haley J Abel
Jessica Walrath
Karlyne M Reilly
Katherine DeSchryver
Melike Pekmezci
Robert S Fulton
P2860
P304
P356
10.1158/1078-0432.CCR-14-3049
P407
P577
2015-04-29T00:00:00Z