Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors.
about
Structures of the inactive and active states of RIP2 kinase inform on the mechanism of activation.Tyrosine kinase inhibitors of Ripk2 attenuate bacterial cell wall-mediated lipolysis, inflammation and dysglycemia.Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann-Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn's disease.Synthetic Biology Reveals the Uniqueness of the RIP Kinase Domain.Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases.The NOD2 receptor is crucial for immune responses towards New World Leishmania species.Activation loop targeting strategy for design of receptor-interacting protein kinase 2 (RIPK2) inhibitors.RIPK2: New Elements in Modulating Inflammatory Breast Cancer Pathogenesis.Emerging Mechanisms of Innate Immunity and Their Translational Potential in Inflammatory Bowel Disease.Unique BIR domain sets determine inhibitor of apoptosis protein-driven cell death and NOD2 complex signal specificityIdentification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel
P2860
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P2860
Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Inflammatory Signaling by NOD- ...... ant Type II Kinase Inhibitors.
@ast
Inflammatory Signaling by NOD- ...... ant Type II Kinase Inhibitors.
@en
type
label
Inflammatory Signaling by NOD- ...... ant Type II Kinase Inhibitors.
@ast
Inflammatory Signaling by NOD- ...... ant Type II Kinase Inhibitors.
@en
prefLabel
Inflammatory Signaling by NOD- ...... ant Type II Kinase Inhibitors.
@ast
Inflammatory Signaling by NOD- ...... ant Type II Kinase Inhibitors.
@en
P2093
P2860
P50
P1476
Inflammatory Signaling by NOD- ...... vant Type II Kinase Inhibitors
@en
P2093
Alex N Bullock
Danish Saleh
Gregory D Cuny
Holm H Uhlig
Jenny L Maki
Soumya Ray
Tobias Schwerd
P2860
P304
P356
10.1016/J.CHEMBIOL.2015.07.017
P577
2015-08-27T00:00:00Z