ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathways
about
The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κBActivation of interferon regulatory factor 5 by site specific phosphorylationA novel motif in the Crohn's disease susceptibility protein, NOD2, allows TRAF4 to down-regulate innate immune responsesUbiquitin signaling in immune responsesUbiquitin in the activation and attenuation of innate antiviral immunityNOD-Like Receptors: Master Regulators of Inflammation and CancerRIP2 activity in inflammatory disease and implications for novel therapeuticsRegulation of inflammatory and antiviral signaling by A20.The ubiquitin system: a critical regulator of innate immunity and pathogen-host interactionsInternational Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and diseaseCYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune SignalingPellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitisLate domain-independent rescue of a release-deficient Moloney murine leukemia virus by the ubiquitin ligase itch.Human ITCH E3 ubiquitin ligase deficiency causes syndromic multisystem autoimmune disease.E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP.Receptor-interacting protein (RIP) kinase family.NOD2 downregulates colonic inflammation by IRF4-mediated inhibition of K63-linked polyubiquitination of RICK and TRAF6.A genome-wide small interfering RNA (siRNA) screen reveals nuclear factor-κB (NF-κB)-independent regulators of NOD2-induced interleukin-8 (IL-8) secretionInhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses.NOD1 and NOD2: signaling, host defense, and inflammatory disease.RIP kinases: key decision makers in cell death and innate immunity.Emerging significance of NLRs in inflammatory bowel disease.Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors.p63 threonine phosphorylation signals the interaction with the WW domain of the E3 ligase ItchReceptor-Interacting Protein Kinase-2 Inhibition by CYLD Impairs Antibacterial Immune Responses in Macrophages.Blau syndrome-associated Nod2 mutation alters expression of full-length NOD2 and limits responses to muramyl dipeptide in knock-in mice.A discrete ubiquitin-mediated network regulates the strength of NOD2 signaling.Ubiquitin regulates caspase recruitment domain-mediated signaling by nucleotide-binding oligomerization domain-containing proteins NOD1 and NOD2.Monoubiquitination of survival motor neuron regulates its cellular localization and Cajal body integrity.Ubiquitin e3 ligase itch negatively regulates osteoblast differentiation from mesenchymal progenitor cellsNOD2, an intracellular innate immune sensor involved in host defense and Crohn's disease.Functions of NOD-Like Receptors in Human Diseases.Ubiquitin E3 ligase Itch negatively regulates osteoclast formation by promoting deubiquitination of tumor necrosis factor (TNF) receptor-associated factor 6.Clomipramine causes osteoporosis by promoting osteoclastogenesis via E3 ligase Itch, which is prevented by Zoledronic acid.Ubiquitin E3 ligase Itch negatively regulates osteoblast function by promoting proteasome degradation of osteogenic proteinsDeubiquitinases in the regulation of NF-κB signaling.The role of NOD1 and NOD2 in host defense against chlamydial infection.Peptidoglycan: a critical activator of the mammalian immune system during infection and homeostasis.Regulation of NF-κB by deubiquitinases.Ubiquitination and phosphorylation in the regulation of NOD2 signaling and NOD2-mediated disease
P2860
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P2860
ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathways
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
ITCH K63-ubiquitinates the NOD ...... nflammatory signaling pathways
@ast
ITCH K63-ubiquitinates the NOD ...... nflammatory signaling pathways
@en
ITCH K63-ubiquitinates the NOD ...... nflammatory signaling pathways
@en-gb
ITCH K63-ubiquitinates the NOD ...... nflammatory signaling pathways
@nl
type
label
ITCH K63-ubiquitinates the NOD ...... nflammatory signaling pathways
@ast
ITCH K63-ubiquitinates the NOD ...... nflammatory signaling pathways
@en
ITCH K63-ubiquitinates the NOD ...... nflammatory signaling pathways
@en-gb
ITCH K63-ubiquitinates the NOD ...... nflammatory signaling pathways
@nl
prefLabel
ITCH K63-ubiquitinates the NOD ...... nflammatory signaling pathways
@ast
ITCH K63-ubiquitinates the NOD ...... nflammatory signaling pathways
@en
ITCH K63-ubiquitinates the NOD ...... nflammatory signaling pathways
@en-gb
ITCH K63-ubiquitinates the NOD ...... nflammatory signaling pathways
@nl
P2093
P2860
P921
P3181
P1433
P1476
ITCH K63-ubiquitinates the NOD ...... nflammatory signaling pathways
@en
P2093
Edward W Harhaj
Jill M Marinis
Lydia E Matesic
Mingfang Tao
Peter C Scacheri
P2860
P304
P3181
P356
10.1016/J.CUB.2009.06.038
P407
P577
2009-08-11T00:00:00Z